Apoptosis News and Research

RSS

Apoptosis is programmed cell death, the body's normal method of disposing of damaged, unwanted, or unneeded cells.

Scientists characterize type I IFN response during SARS-CoV-2 infection

In a recent study posted to the bioRxiv* preprint server, Canadian researchers assessed the impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection on interferon (IFN) response.

15 Jun 2022

Research suggests two protein coding genes can predict severe COVID-19

In a recent study posted to the medRxiv* pre-print server, researchers demonstrated that two genes, GTPase, IMAP Family Member 7 (GIMAP7), and sphingosine-1-phosphate receptor 2 (S1PR2), have the potential to predict severe coronavirus disease 2019 (COVID-19) with ~90% accuracy.

8 Jun 2022

Cofilin could be a potential target for mitigating atherosclerosis at early stage, finds study

A joint research team at LKS Faculty of Medicine, The University of Hong Kong (HKUMed) and Queen Mary University of London (QMUL) has discovered the molecular mechanisms of how pathological condition-mimicking mechanical stimuli lead to the early progression of atherosclerosis, a leading cause of vascular disease worldwide.

8 Jun 2022

New FR-targeting, micropinocytosis-mediated bioconjugate attacks K-Ras mutant pancreatic cancer

Often undetected until it has progressed to an advanced stage, pancreatic ductal adenocarcinoma (PDAC) is a lethal cancer.

6 Jun 2022

Researchers identify chemical compound that may short-circuit brain cell death in Parkinson's disease

In studies in mice, Johns Hopkins Medicine researchers say they have identified a chemical compound that stops the final events in the pathway linked to the death of brain cells in Parkinson's disease.

1 Jun 2022

2-Deoxy-D-glucose may inhibit coronaviruses and rhinoviruses

Scientists demonstrated the use of 2-deoxy-D-glucose (2-DG) as a wide-spectrum antiviral agent targeting viruses such as SARS-CoV-2.

27 May 2022

The role of pyroptosis in COVID-19

Researchers investigate the mechanisms by which SARS-CoV-2 induces NLRP3 inflammasome formation leading to pyroptosis.

25 May 2022

NYU Abu Dhabi research could pave the way for more effective cancer treatments

A team led by Professor of Biology, Senior Vice Provost of Research at NYU Abu Dhabi, and UAE national Sehamuddin Galadari, has discovered a novel structural modification in AMP-activated protein kinase (AMPK) during anticancer therapy that could pave the way for the development of more effective cancer treatments.

25 May 2022

Study reveals how ZBP1 could lead to a cytokine storm during COVID-19

Scientists from St. Jude Children's Research Hospital have shown that the innate immune sensor, ZBP1, and its associated inflammatory cell death pathway, PANoptosis, are major contributors to the negative effects of interferon treatment and high interferon levels in some COVID-19 patients.

20 May 2022

Study explores if prior infection with SARS-CoV-2 increased sensitivity to a mitochondrial toxin known to induce parkinsonism

The authors of the current study looked at the potential for an increased risk of parkinsonism following a bout of SARS-CoV-2 infection through accepted post-viral mechanisms.

20 May 2022

Good lifestyle habits during menopause can help alleviate the health risks related to fat accumulation

A study conducted in the Faculty of Sport and Health Sciences at the University of Jyväskylä, Finland, revealed that menopausal transition increases women's body fat, especially in the waist area.

19 May 2022

Exosomes derived from γδ-T cells synergized with radiotherapy can control nasopharyngeal carcinoma

A research team at LKS Faculty of Medicine, The University of Hong Kong discovered that exosomes derived from γδ-T cells (γδ-T-Exos) synergised with radiotherapy can control nasopharyngeal carcinoma (NPC) by overcoming the radioresistance of NPC cancer stem cells (CSCs) and preserve their tumor-killing and T cell-promoting activities in the immunosuppressive NPC microenvironment.

18 May 2022

Impact of cannabidiol on cellular innate immune responses to SARS-CoV-2 genes

A new study published in the journal Life Sciences has focused on examining the effects of ORF8 and ORF10 genes and SARS-CoV-2 Membrane (M) protein on apoptosis.

17 May 2022

Novel Type 1 diabetes treatment involves pancreatic islet transplant without the need for immunosuppression

In a new study, a team of researchers from the University of Missouri, Georgia Tech and Harvard University has demonstrated the successful use of a novel Type 1 diabetes treatment in a large animal model.

13 May 2022

Hormonal shift during menopause changes women’s blood metabolite profile

In midlife, the risk of cardiometabolic diseases increases in women more rapidly than in men. A study performed at the Faculty of Sport and Health Sciences of the University of Jyväskylä shows that changes in blood metabolite profile accompany the shift in sex hormone levels during menopause.

13 May 2022

Researchers discover new gene that confers resistance to prostate cancer treatment

Northwestern Medicine investigators have identified a gene that confers resistance to a common prostate cancer treatment, according to a study published in Cancer Research.

13 May 2022

Research describes how DNA damage can affect neural health and function

A new research paper in the journal EMBO Reports describes how DNA damage can affect neural health and function.

12 May 2022

Vaccine features that could induce durable humoral immune responses against SARS-CoV-2

A new study explored key vaccine features which could help induce and preserve humoral immunity against SARS-CoV-2 infection.

11 May 2022

A hybrid, multiscale, individual-based model to study the within-host spread of SARS-CoV-2 and the subsequent innate immune response

In this study, the authors have specifically studied the interactions of epithelial cells, a subset of cytokines and macrophages.

10 May 2022

Study investigates the cause of lymphopenia as seen in COVID-19 patients

Researchers explored the underlying mechanism resulting in thymic atrophy and subsequent lymphopenia in COVID-19 patients.

9 May 2022

Apoptosis News and Research

Scientists characterize type I IFN response during SARS-CoV-2 infection

Research suggests two protein coding genes can predict severe COVID-19

Cofilin could be a potential target for mitigating atherosclerosis at early stage, finds study

New FR-targeting, micropinocytosis-mediated bioconjugate attacks K-Ras mutant pancreatic cancer

Researchers identify chemical compound that may short-circuit brain cell death in Parkinson's disease

2-Deoxy-D-glucose may inhibit coronaviruses and rhinoviruses

The role of pyroptosis in COVID-19

NYU Abu Dhabi research could pave the way for more effective cancer treatments

Study reveals how ZBP1 could lead to a cytokine storm during COVID-19

Study explores if prior infection with SARS-CoV-2 increased sensitivity to a mitochondrial toxin known to induce parkinsonism

Good lifestyle habits during menopause can help alleviate the health risks related to fat accumulation

Exosomes derived from γδ-T cells synergized with radiotherapy can control nasopharyngeal carcinoma

Impact of cannabidiol on cellular innate immune responses to SARS-CoV-2 genes

Novel Type 1 diabetes treatment involves pancreatic islet transplant without the need for immunosuppression

Hormonal shift during menopause changes women’s blood metabolite profile

Researchers discover new gene that confers resistance to prostate cancer treatment

Research describes how DNA damage can affect neural health and function

Vaccine features that could induce durable humoral immune responses against SARS-CoV-2

A hybrid, multiscale, individual-based model to study the within-host spread of SARS-CoV-2 and the subsequent innate immune response

Study investigates the cause of lymphopenia as seen in COVID-19 patients

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

Latest News