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Novel therapeutic eradicates gastric cancer in treated mice

A novel cancer therapeutic, combining antibody fragments with molecularly engineered nanoparticles, permanently eradicated gastric cancer in treated mice, a multi-institutional team of researchers found.

17 Mar 2023

Computational analysis of large genetic datasets reveals rare disease etiologies

Using a new computational approach they developed to analyze large genetic datasets from rare disease cohorts, researchers at the Icahn School of Medicine at Mount Sinai and colleagues have discovered previously unknown genetic causes of three rare conditions: primary lymphedema (characterized by tissue swelling), thoracic aortic aneurysm disease, and congenital deafness.

17 Mar 2023

Does vitamin D play an anti-viral role against SARS-CoV-2?

Researchers screened various compounds for anti-viral properties against SARS-CoV-2.

17 Mar 2023

Creating more effective and safe treatments for COVID-19

When approaching a task, members of a team need to work in synergy. Nothing can be accomplished if you're pulling in different directions.

16 Mar 2023

Using probiotics to treat depression

Researchers discuss whether probiotics could be used as supplementary or primary therapy to manage major depressive disorder.

15 Mar 2023

Researchers shine new light on a potential target for the treatment of diabetic nephropathy

The kidneys perform a critical role in the body by removing waste and excess fluid in the form of urine. In a condition known as diabetic nephropathy, complications from diabetes disrupt the ability of the kidneys to function properly.

15 Mar 2023

Researchers identify a potential treatment to prevent severe COVID-19 in high-risk patients

UVA Health researchers have identified a potential treatment to prevent severe COVID-19 in patients at great risk.

15 Mar 2023

Newly identified small molecule may help treat people with drug-resistant epilepsy

Researchers at Tufts University School of Medicine and colleagues have identified a small molecule that may help treat people with epilepsy whose condition has become resistant to the benzodiazepine drugs usually used in managing seizures.

15 Mar 2023

Clinical trial shows promising results for oral psoriasis treatment

A company launched from The University of Queensland's Institute for Molecular Bioscience (IMB) has passed an important milestone in developing an oral treatment for the common skin disease psoriasis.

15 Mar 2023

Owlstone Medical Enters Partnership with Bicycle Therapeutics for the Development of Antigen-Targeted EVOC Probes for Early Cancer Detection

Owlstone Medical, the global leader in Breath Biopsy® announced that it has entered into a Research Agreement with Bicycle Therapeutics plc.

15 Mar 2023

Understanding how cells adjust in real time to withstand stresses on our health

Every minute of every day, our body adapts to meet the needs of each moment. When we binge on carbs, exercise, or become sick, chemical reactions inside our cells switch on, slow down, or shift strategy so that we have the energy and strength we need.

14 Mar 2023

Researchers identify the mSWI/SNF chromatin remodeling complex as a host-directed drug target for SARS-CoV-2 infection

Researchers showed that mammalian SWItch/Sucrose Non-Fermentable (mSWI/SNF) chromatin remodeling complexes represent a potential class of host-directed broad-acting SARS-CoV-2 therapeutic targets.

14 Mar 2023

Schizophrenia risk conferred by rare damaging genetic variants is conserved across ethnicities

Researchers have identified two previously unknown genes linked to schizophrenia and newly implicated a third gene as carrying risk for both schizophrenia and autism.

13 Mar 2023

The right combination of bile salt hydrolases may offer a new approach to treat C. diff

Not all probiotics are created equal. In a new study, researchers found that certain enzymes within a class known as bile salt hydrolases (BSHs) can restrict Clostridioides difficile (C. diff.) colonization by both altering existing bile acids and by creating a new class of bile acids within the gut's microbial environment.

13 Mar 2023

Therapeutics News and Research

Novel therapeutic eradicates gastric cancer in treated mice

Computational analysis of large genetic datasets reveals rare disease etiologies

Does vitamin D play an anti-viral role against SARS-CoV-2?

Creating more effective and safe treatments for COVID-19

Using probiotics to treat depression

Researchers shine new light on a potential target for the treatment of diabetic nephropathy

Researchers identify a potential treatment to prevent severe COVID-19 in high-risk patients

Newly identified small molecule may help treat people with drug-resistant epilepsy

Clinical trial shows promising results for oral psoriasis treatment

Owlstone Medical Enters Partnership with Bicycle Therapeutics for the Development of Antigen-Targeted EVOC Probes for Early Cancer Detection

Understanding how cells adjust in real time to withstand stresses on our health

Researchers identify the mSWI/SNF chromatin remodeling complex as a host-directed drug target for SARS-CoV-2 infection

Schizophrenia risk conferred by rare damaging genetic variants is conserved across ethnicities

The right combination of bile salt hydrolases may offer a new approach to treat C. diff

Exploring airway-to-brain sensory pathways in influenza-induced illness

Injectable peptide used for type 2 diabetes shows potential for treating 'blinding' IIH headaches

Minimally invasive technique for fixing bunions does not make flatfoot worse, study shows

UB researchers develop new tool to assess the presence and severity of sarcopenia

New tool allows researchers to perform genetic screens of cell-cell interactions

The 2022 NICE guidelines for the diagnosis and management of gout

Understanding the DNA Damage Response in Innate Immunity eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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