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Rapid AAV Titer for Bioprocessing in Gene Therapy

In this article, News-Medical talks to Sartorius about biosensing and bioprocessing in gene therapy, while also discussing the various products Sartorius produces in order to aid in this.

From Sartorius 27 Feb 2023

Study establishes new pre-clinical model to develop clinically relevant treatments for heart attacks

CÚRAM SFI Research Centre for Medical Devices researchers have published in Nature Communications a key study establishing a new pre-clinical model to develop clinically relevant treatments for heart attacks.

24 Feb 2023

UVA research provides new insight into common causes of vision loss

UVA Health scientists have discovered an unknown contributor to harmful blood vessel growth in the eye that could lead to new treatments for blinding macular degeneration and other common causes of vision loss.

24 Feb 2023

Study shows the beneficial effect of verapamil in children with newly-diagnosed type 1 diabetes

Published in JAMA, a University of Minnesota led study shows that verapamil, a drug commonly used to treat high blood pressure and heart conditions, can have a beneficial effect on the pancreas in children with newly-diagnosed type 1 diabetes (T1D).

24 Feb 2023

Digital cognitive behavioral therapy reduces blood sugar levels in patients with diabetes

People with Type 2 diabetes who were given a smartphone app that delivers personalized cognitive behavioral therapy (CBT) saw significantly greater reductions in their blood sugar and less need for higher doses of diabetes medications at six months compared with those who only received standard diabetes care and a control app, in a study presented at the American College of Cardiology's Annual Scientific Session Together With the World Congress of Cardiology.

24 Feb 2023

Cryo-EM imaging reveals molecular machine’s secret weapon

RNAs are having a moment. The foundation of COVID-19 vaccines, they've made their way from biochemistry textbooks into popular magazines and everyday discussions. Entire companies have launched dedicated to RNA research.

24 Feb 2023

Skipping meals can trigger a negative effect on immune cells

Fasting may be detrimental to fighting off infection, and could lead to an increased risk of heart disease, according to a new study by the Icahn School of Medicine at Mount Sinai.

23 Feb 2023

New ensemble learning model could predict dementia in older drivers with excellent accuracy

Using ensemble learning techniques and longitudinal data from a large naturalistic driving study, researchers at Columbia University's Mailman School of Public Health, Fu Foundation School of Engineering and Applied Science, and Vagelos College of Physicians and Surgeons have developed a novel, interpretable and highly accurate algorithm for predicting mild cognitive impairment and dementia in older drivers.

23 Feb 2023

Scientific advice on the terminal sterilization of oligonucleotide drug products

A new report, coauthored by several major pharmaceutical companies, reviews the current state of sterile oligonucleotide drug product processing.

22 Feb 2023

Scientists identify mechanisms underlying autoimmunity in Down syndrome

Scientists at the Icahn School of Medicine at Mount Sinai in New York have identified which parts of the immune system go awry and contribute to autoimmune diseases in individuals with Down syndrome.

22 Feb 2023

Mount Sinai study sheds new light on the role of DNA methylation in Alzheimer's disease

Mount Sinai researchers have published a study in Alzheimer's & Dementia: The Journal of the Alzheimer's Association that sheds new light on the role of DNA methylation in Alzheimer's disease (AD).

22 Feb 2023

Researchers reveal the metabolic reactions upon activating Akt2 enzyme

Takeaki Ozawa and his team from the University of Tokyo reveal the metabolic reactions upon activating an enzyme called Akt2. In doing so, they reveal the inner workings of insulin-regulated metabolism.

21 Feb 2023

First induced bat iPSCs offer insights into the close relationship between bats and SARS-CoV-2 viruses

Researchers from the Icahn School of Medicine at Mount Sinai have generated the first induced pluripotent stem cells (iPSCs) from bats, gaining valuable insights into the close relationship between bats and viruses.

21 Feb 2023

Oxford-Harrington Rare Disease Centre hosts virtual event in honor of the upcoming Rare Disease Day

The Oxford-Harrington Rare Disease Centre, a partnership of the University of Oxford and Harrington Discovery Institute at University Hospitals, is hosting a virtual event on Monday, Feb. 27, 2023, in honor of the upcoming Rare Disease Day, which is celebrated across the globe on February 28 every year.

21 Feb 2023

First fully human ovarian organoids provide insights about female reproductive health and disease

Despite the fact that we all start out as an egg cell in one of our mother's ovaries, these human reproductive organs are surprisingly under-studied.

21 Feb 2023

Structure of DREADD designer receptor could pave the way for creating next generation tools

In order to more fully understand how diseases arise in the brain, scientists must unravel the intricate way neurons relay messages (either chemical or electrical) along a complex web of nerve cells.

20 Feb 2023

COVID-19 vaccination associated with fewer heart attacks, strokes, and other cardiovascular issues

Analyzing the most extensive datasets in the United States, researchers from the Icahn School of Medicine at Mount Sinai have revealed that vaccination against COVID-19 is associated with fewer heart attacks, strokes, and other cardiovascular issues among people who were infected with SARS-CoV-2, the virus that causes COVID-19.

20 Feb 2023

Therapeutics News and Research

Rapid AAV Titer for Bioprocessing in Gene Therapy

Study establishes new pre-clinical model to develop clinically relevant treatments for heart attacks

UVA research provides new insight into common causes of vision loss

Study shows the beneficial effect of verapamil in children with newly-diagnosed type 1 diabetes

Digital cognitive behavioral therapy reduces blood sugar levels in patients with diabetes

Cryo-EM imaging reveals molecular machine’s secret weapon

Skipping meals can trigger a negative effect on immune cells

New ensemble learning model could predict dementia in older drivers with excellent accuracy

Scientific advice on the terminal sterilization of oligonucleotide drug products

Scientists identify mechanisms underlying autoimmunity in Down syndrome

Mount Sinai study sheds new light on the role of DNA methylation in Alzheimer's disease

Researchers reveal the metabolic reactions upon activating Akt2 enzyme

First induced bat iPSCs offer insights into the close relationship between bats and SARS-CoV-2 viruses

Oxford-Harrington Rare Disease Centre hosts virtual event in honor of the upcoming Rare Disease Day

First fully human ovarian organoids provide insights about female reproductive health and disease

Structure of DREADD designer receptor could pave the way for creating next generation tools

COVID-19 vaccination associated with fewer heart attacks, strokes, and other cardiovascular issues

Utilizing CRISPR to discover new therapy options for COPD

“Cell food” reveals how different metabolic programs regulate T cell persistence

Mechanistic insight into how receptor location is the key for psychedelic drug effects

Industry Focus eBook - Microbiome (1st edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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