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Persistent gut microbiome changes linked to sustained colorectal cancer risk

More than a decade after removal of an adenoma-a precancerous mass-from the colon, alterations to the gut microbiome and metabolites remain and may drive heightened risk of colorectal cancer (CRC), according to a new study led by researchers at Harvard T.H. Chan School of Public Health.

27 May 2026

Extreme trait values often have simpler genetic explanations than thought

Researchers at the Icahn School of Medicine at Mount Sinai have found evidence that people who fall at the extreme high or low ends of certain traits, such as cholesterol, blood glucose, height, and age at menopause, are more likely to have a simple genetic explanation than previously thought.

27 May 2026

Naturally occurring peptide can reverse drug resistance in melanoma

Melanoma is one of the deadliest forms of skin cancer, due in large part to its ability to rapidly develop resistance to treatment.

27 May 2026

Combat Medical highlights patient impact of HIVEC HEAT trial at the American Urological Association Annual Meeting

Combat Medical (Combat), a medical device company optimizing the delivery and efficacy of cancer therapeutics, today announced an update on its HIVEC® HEAT FDA registration trial at The American Urological Association (AUA) Annual Meeting.

From Combat Medical 27 May 2026

Urine test may help identify autism risk in children

A simple urine test may help identify children at risk for autism sooner than current assessments - opening the door for earlier diagnosis and treatment, and better long-term outcomes for children who do have autism spectrum disorder.

26 May 2026

Scientists target root of relapse in aggressive childhood brain tumors

Stopping cancer from coming back is the goal of new research from MUSC Hollings Cancer Center, where scientists are targeting cells that fuel the return of an aggressive pediatric brain tumor.

26 May 2026

New AI tools identify potential drugs for rare Ebola virus

Recent advances in artificial intelligence have enabled Southwest Research Institute (SwRI) to identify nearly two dozen antiviral compounds that could potentially treat a rare species of Ebola virus (Bundibugyo virus) currently affecting the Democratic Republic of Congo.

26 May 2026

Hydroxychloroquine lowers heart risks in skin lupus patients

A study led by investigators from Johns Hopkins Medicine found that some patients with discoid lupus erythematosus - a form of skin lupus commonly diagnosed in young to middle-aged Black women that causes disc-shaped plaques to form on the body - were less likely to experience complications, such as diabetes, hypertension and coronary artery disease if they were prescribed hydroxychloroquine.

26 May 2026

Ohio State study unlocks the long-standing mystery of RNA interference

While scientists have known for over two decades that all cells use a strategy called RNA interference to regulate gene expression, a new study is the first to describe how a specific protein manages the step-by-step process of assembling the molecular complex that performs the regulatory job.

26 May 2026

New AI model predicts cancer treatment responses from mutations

Researchers at University of California San Diego have developed a new artificial intelligence (AI) model that can translate a tumor's complex genetic profile into predictions about how that cancer may respond to treatment.

26 May 2026

Pioneering cell therapy offers hope for advanced liver disease

A new type of cell therapy shows promise as the first treatment for advanced liver disease, following results from a clinical trial.

25 May 2026

Ferroptosis exploits unique cancer metabolic vulnerabilities to bypass traditional apoptotic evasion pathways

A new wave of scientific understanding is placing ferroptosis, a distinct form of iron-dependent cell death, at the forefront of efforts to overcome drug resistance in digestive cancers. These cancers, which include gastric, colorectal, liver, pancreatic, and esophageal malignancies, remain among the most challenging to treat due to their ability to evade standard therapies.

25 May 2026

Small non-coding RNA molecule precisely controls vital gene expression and cellular balance

A rapidly advancing area of biomedical innovation is shining a spotlight on miR-128-3p, a small yet powerful molecule with the potential to reshape how diseases—especially cancer—are detected, monitored, and treated. This microRNA, part of a broader class of non-coding RNAs, plays a critical role in regulating gene activity and maintaining cellular homeostasis.

25 May 2026

Metabolic reprogramming helps tumor cells adapt and evade the human immune system

A newly published review article highlights the critical role of fatty acid metabolism in shaping the tumor microenvironment and influencing cancer progression, offering fresh perspectives for the development of more effective therapies.

25 May 2026

Sting signaling stimulates vital immune defenses to actively suppress aggressive tumor growth

A new review brings attention to the STING pathway as a critical regulator in both colitis and colon cancer, highlighting its complex and often opposing roles in inflammation and tumor development. The findings underscore how this key component of the innate immune system can act as both a driver of disease and a protective mechanism, depending on biological context.

25 May 2026

New review highlights how glutamine metabolism shapes the complex tumor microenvironment

A new review article highlights the expanding importance of glutamine metabolism in shaping the tumor microenvironment, offering fresh perspectives on how metabolic interactions influence cancer progression and therapeutic response

25 May 2026

New advances improve prevention and treatment of HPV-related cancers

A new review article is drawing attention to the growing global impact of human papillomavirus (HPV) and the rapid progress in vaccines and therapeutic strategies aimed at reducing the burden of cervical and non-cervical cancers.

24 May 2026

RNA regulator RBM15 linked to immunity, metabolism, and cancer progression

A newly published review article brings attention to the expanding role of RBM15, a critical regulator of RNA m6A methylation, in the development and progression of a wide range of diseases, including cancer, metabolic disorders, and cardiovascular conditions.

24 May 2026

Efferocytosis plays central role in wound healing and tissue repair

A new review shines a spotlight on efferocytosis, a critical biological process responsible for the removal of dead cells, as a central force in promoting efficient wound repair and maintaining tissue balance.

24 May 2026

DNA methylation variability may improve precision cancer treatment strategies

A new review article brings attention to the critical role of DNA methylation heterogeneity in shaping the tumor microenvironment, highlighting its growing importance in understanding cancer progression and advancing more precise treatment strategies.

24 May 2026