Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

CN Bio introduces the PhysioMimix™ OOC Multi-Organ Microphysiological System

CN Bio today announced the commercial launch of its new PhysioMimix™ OOC Multi-Organ MPS.

From CN Bio 17 Mar 2021

Adequate reimbursement for molecular diagnostic tests can improve patient care

The Association for Molecular Pathology (AMP), the premier global, molecular diagnostic professional society, today released the results of its qualitative and quantitative "Analysis of Professional Work Effort in Molecular Test Interpretation Report."

17 Mar 2021

Novel protein construct prevents lethal COVID-19 in mice

Researchers in the United States have developed a novel protein that prevented lethal disease among mice infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19).

16 Mar 2021

Combination therapy may reduce influenza-associated morbidity and mortality

A significant proportion of hospitalized patients with influenza develop complications of acute respiratory distress syndrome, driven by virus-induced cytopathic effects as well as exaggerated host immune response.

16 Mar 2021

Study proves that postural orthostatic tachycardia syndrome may be an autoimmune disorder

The symptoms of postural orthostatic tachycardia syndrome, or POTS, can be as varied as they are confounding. There can be fatigue, pain, bleeding disorders and anxiety. Heart palpitations and lightheadedness are common.

16 Mar 2021

Study finds significant variation in biomarker test utilization and treatment for non–small-cell lung cancer

Biomarker testing surveys specific disease-associated molecules to predict treatment response and disease progression; however its use has complicated the diagnosis of non-small-cell lung cancer (NSCLC).

15 Mar 2021

Less-educated, unmarried patients less likely to undergo a transplant for mantle cell lymphoma

Mantle cell lymphoma is a malignant disease in which intensive treatment can prolong life. In a new study, scientists from Uppsala University and other Swedish universities show that people with mantle cell lymphoma who were unmarried, and those who had low educational attainment, were less often treated with a stem-cell transplantation, which may result in poorer survival.

13 Mar 2021

Neutralizing antibodies induced by COVID-19 vaccines less effective against new variants

SARS-CoV-2, the virus that causes COVID-19, has mutated throughout the pandemic. New variants of the virus have arisen throughout the world, including variants that might possess increased ability to spread or evade the immune system.

13 Mar 2021

Impact of type I interferon (IFN) autoantibodies in critical COVID-19

A new preprint discusses the pathogenesis of this critical COVID-19 with reference to autoimmune phenomena involving the key antiviral type I interferon pathway.

12 Mar 2021

Study shows how functional biomaterials rely on interfacial protein layer to transmit signals to living cells

An interdisciplinary research team at Lehigh University has unraveled how functional biomaterials rely upon an interfacial protein layer to transmit signals to living cells concerning their adhesion, proliferation and overall development

12 Mar 2021

Study: Lowering the activity of KRAS gene can help fight pancreatic cancer

If clinicians could stop mutations of the KRAS gene in pancreatic cancer – which happens in more than 90 percent of pancreatic cancer cases and drastically reduces response to immunotherapy – the chances of improving treatment for this deadly form of cancer would be increased.

11 Mar 2021

Whole genome sequencing may guide blood cancer treatment

For certain blood cancers, such as acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS), deciding whether patients need an aggressive treatment typically hinges on a set of lab tests to identify genetic changes.

11 Mar 2021

Simple blood test using nanoparticles could enable earlier detection of acute liver damage

University of Texas at Dallas chemist Dr. Jie Zheng has spent much of his career investigating gold nanoparticles for their potential impact in the field of nanomedicine.

10 Mar 2021

Researchers study the effects of cocaine on patients diagnosed with schizophrenia

Alejandro Fuertes-Saiz, fourth-year Psychiatry intern at the Hospital Provincial de Castellón and doctoral candidate at the CEU Cardenal Herrera (CEU UCH) University of Valencia, along with his thesis directors, Gonzalo Haro and Ana Benito, have just published in journal Brain Science the final results of three year-long research where they have studied the effects of cocaine on patients diagnosed with schizophrenia or antisocial personality disorder.

10 Mar 2021

Research reveals link between proteins causing Alzheimer's disease and age-related sight loss

Newly published research has revealed a close link between proteins associated with Alzheimer's disease and age-related sight loss.

10 Mar 2021

Huron Digital Pathology Receives CE-IVD Mark for TissueScope iQ Scanner

Huron Digital Pathology has received a CE-IVD mark for its high throughput TissueScope iQ 400 slide whole slide scanner.

From Huron Technologies 10 Mar 2021

Researchers develop AI-based tissue-section analysis system to diagnose breast cancer

Researchers at Charité - Universitätsmedizin Berlin and TU Berlin as well as the University of Oslo have developed a new tissue-section analysis system for diagnosing breast cancer based on artificial intelligence (AI).

10 Mar 2021

Phase 2 clinical trial is now open at Columbia to test gene therapy for dry macular degeneration

A phase 2 clinical trial is underway at Columbia University and NewYork-Presbyterian to test an investigational gene therapy for dry age-related macular degeneration, a progressive, chronic eye disease with no cure and a leading cause of blindness in the United States.

9 Mar 2021

Somatic gene mutations in brain cells could contribute to schizophrenia pathology

Schizophrenia is a neurodevelopmental disorder that disrupts brain activity producing hallucinations, delusions, and other cognitive disturbances. Researchers have long searched for genetic influences in the disease, but genetic mutations have been identified in only a small fraction--fewer than a quarter--of sequenced patients.

9 Mar 2021

Optimized SARS-CoV-2 vaccine candidate could be less reactogenic, say researchers

A new study, released as a preprint on the bioRxiv* server, reports an optimized coronavirus disease 2019 (COVID-19) vaccine candidate, which, claim the researchers, may be less likely to produce reactions like fevers. It may also have increased protective potential against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the pathogen that causes COVID-19.

9 Mar 2021

Pathology News and Research

Further Reading

CN Bio introduces the PhysioMimix™ OOC Multi-Organ Microphysiological System

Adequate reimbursement for molecular diagnostic tests can improve patient care

Novel protein construct prevents lethal COVID-19 in mice

Combination therapy may reduce influenza-associated morbidity and mortality

Study proves that postural orthostatic tachycardia syndrome may be an autoimmune disorder

Study finds significant variation in biomarker test utilization and treatment for non–small-cell lung cancer

Less-educated, unmarried patients less likely to undergo a transplant for mantle cell lymphoma

Neutralizing antibodies induced by COVID-19 vaccines less effective against new variants

Impact of type I interferon (IFN) autoantibodies in critical COVID-19

Study shows how functional biomaterials rely on interfacial protein layer to transmit signals to living cells

Study: Lowering the activity of KRAS gene can help fight pancreatic cancer

Whole genome sequencing may guide blood cancer treatment

Simple blood test using nanoparticles could enable earlier detection of acute liver damage

Researchers study the effects of cocaine on patients diagnosed with schizophrenia

Research reveals link between proteins causing Alzheimer's disease and age-related sight loss

Huron Digital Pathology Receives CE-IVD Mark for TissueScope iQ Scanner

Researchers develop AI-based tissue-section analysis system to diagnose breast cancer

Phase 2 clinical trial is now open at Columbia to test gene therapy for dry macular degeneration

Somatic gene mutations in brain cells could contribute to schizophrenia pathology

Optimized SARS-CoV-2 vaccine candidate could be less reactogenic, say researchers

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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