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New study helps explain why lung tumors turn aggressive

Lung cancer is the number 1 killer among cancers, especially when it is of the non-small cell type. Among these, adenocarcinomas are the most common and aggressive type. These tumors also show a strong tendency to show dedifferentiation, or loss of the features that characterize a mature lung cell.

28 Aug 2019

New study reveals exosome-mediated communication between mother and baby

During pregnancy, the mother and the baby communicate in a variety of ways. For instance, signals from the fetus are crucially involved in the initiation of labor and delivery.

22 Aug 2019

Type 1 diabetes linked to gut microbiome and genetic factors

A new study has revealed that the gut microbiome of children with a high genetic risk of developing type 1 diabetes is markedly different from those who have a low risk of the condition.

20 Aug 2019

Genetic risk for autoimmunity may be linked to differences in gut microbiome

Children with increased genetic risk of type 1 diabetes have different gut microbiomes than those with low risk, a new study found.

20 Aug 2019

Genetic variant increases risk of addiction in the presence of childhood stress

What causes some people to become alcoholics or drug abusers when faced with stress, but not others? This question has plagued addiction researchers for decades.

19 Aug 2019

Alzheimer's gene may affect cognitive health before adulthood, study finds

The Apolipoprotein E (APOE) is a major cholesterol carrier that aids in lipid transport and injury repair in the brain. It packages cholesterol and other fats and moves them through the bloodstream. APOE polymorphic alleles are the major genetic factors for the risk of Alzheimer’s disease (AD).

19 Jul 2019

Researchers identify genetic factor linked to development of diabetic peripheral neuropathy

Researchers from Joslin Diabetes Center, using a genome-wide association study, have identified a genetic factor linked to the development of diabetic peripheral neuropathy.

12 Jun 2019

'Eye-in-a-dish' model helps scientists to uncover 'surprising' AMD gene variant

Researchers have discovered a new genetic variant responsible for blood vessel dysregulation in the development of age-related macular degeneration (AMD).

29 May 2019

Scientists develop new genetic tool to modify and understand gene function

Scientists of the National Center for Cardiovascular Research led by Rui Benedito have developed a new genetic tool (iSuRe-Cre) that provides certainty in Cre-inducible genetic modifications, a key technique for understanding gene function.

22 May 2019

AMP offers recommendations to aid in design and validation of clinical CYP2C9 assays

The Association for Molecular Pathology, the premier global, molecular diagnostic professional society, today published consensus, evidence-based recommendations to aid in the design and validation of clinical CYP2C9 assays, promote standardization of testing across different laboratories and improve patient care.

10 May 2019

CoGEN Congress 2019: Speakers' overviews

Update on the use of exome sequencing for the diagnosis of fetal abnormalities

2 May 2019

Scientists develop new video game that may help in the study of Alzheimer's

How do we find our way around? Why do I always get lost while my friend never does? Why does people's sense of direction vary so widely in general? Is it linked to inherent, genetic characteristics or determined by cultural factors?

25 Apr 2019

APOE gene impacts sleep depending on gender and severity of Alzheimer's

The gene most often associated with risk of Alzheimer's Disease impacts sleep depending on gender and the severity of Alzheimer's in a patient, suggests a study led by researchers at the Keenan Research Centre for Biomedical Science.

15 Apr 2019

Scientists develop new CRISPR-based 'allelic drive'

New CRISPR-based gene drives and broader active genetics technologies are revolutionizing the way scientists engineer the transfer of specific traits from one generation to another.

10 Apr 2019

UAB aging and longevity experts receive international prize

University of Alabama at Birmingham aging expert -- and once-upon-a-time lion trainer -- Steven Austad, Ph.D., and UAB postdoctoral fellow in longevity research Jessica Hoffman, Ph.D., have won the George C. Williams prize from the International Society for Evolution, Medicine and Public Health, or ISEMPH.

29 Mar 2019

Air Force develops genetic test to predict mental performance

A research psychologist at the Air Force Research Laboratory can predict your mental performance from a cheek swab or blood sample.

22 Mar 2019

Association found between gene variant and lung disease in the form of systemic vasculitis

University of Tsukuba-led team reveals the association between a gene variant and a lung disease in the form of systemic vasculitis particularly prevalent in the Japanese, potentially providing a target for future therapies.

13 Mar 2019

Researchers identify gene that increases risk of antibiotic reaction

Researchers at Vanderbilt University Medical Center and colleagues have identified a gene that increases the risk for a severe and potentially life-threatening reaction to the commonly prescribed antibiotic vancomycin.

11 Mar 2019

Common fungus found on skin may cause inflammatory bowel disease

Therapies that target certain commensal fungi could provide a new way of treating inflammatory bowel disease (IBD), according to researchers.

6 Mar 2019

New molecular engineering method improves precision of biomarker analysis

Researchers from the University of Helsinki in cooperation with the University of Tartu, Competence Centre on Health Technologies from Estonia, and the Karolinska Institute, published an article in Nature's partner journal Genomic Medicine in which they present Targeted Allele Counting by sequencing along with several of its potential applications.

8 Jan 2019