Mesenchymal Stem Cells News and Research

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Gut microbiota and short chain fatty acids influence bone health in postmenopausal osteoporosis

Postmenopausal osteoporosis (PMOP) is framed as a systemic bone disease driven by estrogen withdrawal, but emerging evidence positions gut dysbiosis and its fermentation products—short-chain fatty acids (SCFAs)—as equally influential regulators of skeletal fate.

6 Aug 2025

Novel DNA plasmid therapy shows high success rate in treating chronic pain in dogs

Elenagen™, a novel DNA plasmid therapy that previously demonstrated high clinical benefit and low toxicity in cancer patients, has now shown significant promise in alleviating chronic pain demonstrating a 90% success rate.

23 Jul 2025

Artificial intelligence tracks aging and damaged cells through high resolution imaging

A combination of high-resolution imaging and machine learning, also known as artificial intelligence (AI), can track cells damaged from injury, aging, or disease, and that no longer grow and reproduce normally, a new study shows.

8 Jul 2025

New technique aligns stem cells to boost healing power

A new way to grow stem cells may help them release more of the signaling proteins they use to repair tissue, potentially improving future treatments.

4 Jul 2025

Breakthrough dual-drug hydrogel promotes cartilage repair in osteoarthritis

A research team from Northwest University, China, has developed a breakthrough nano-composite hydrogel system to address the dual challenges of inflammation and cartilage damage in osteoarthritis (OA), a leading cause of joint disability worldwide.

3 Jul 2025

Targeting the tumor microenvironment to improve osteosarcoma outcomes

The complex tumor microenvironment (TME) in osteosarcoma is emerging as a critical factor in disease progression and treatment resistance.

26 Jun 2025

New technique boosts production of canine stem cells for veterinary use

Mesenchymal stem cells (MSCs), which can be harvested from fat and bone marrow, have immune-modulating and anti-inflammatory effects that are beneficial for both human and veterinary medicine.

20 Jun 2025

Lipid accumulation levels reveal hidden osteoporosis risk

Researchers investigate the use of lipid accumulation products as a predictor of osteoporosis.

14 May 2025

NAD+ restoration improves mitochondrial function in Werner syndrome cells

A new research paper was published in Aging (Aging-US) on April 2, 2025, as the cover of Volume 17, Issue 4, titled "Decreased mitochondrial NAD+ in WRN deficient cells links to dysfunctional proliferation."

2 May 2025

Network pharmacology analysis reveals HXTL mechanism in treating postmenopausal osteoporosis

Huo Xue Tong Luo Capsule (HXTL) has been clinically used to treat osteonecrosis of the femoral head, osteoporosis, and other bone and joint diseases with promising effects.

24 Apr 2025

Boost your transfection success with these proven expert tips

Gain expert insights in this interview on achieving transfection success. Explore proven strategies to optimize your approach and enhance results.

From Sartorius 22 Apr 2025

NKD2 protein discovery opens up new possibilities in the fight against bone loss

A transformative study has uncovered the pivotal role of the protein Naked cuticle homolog 2 (NKD2) in regulating the differentiation of bone-forming osteoblasts and bone-resorbing osteoclasts.

17 Mar 2025

Pitt study uncovers a novel trigger of deadly form of ovarian cancer

Researchers at the University of Pittsburgh have identified a novel trigger of a deadly form of ovarian cancer: a subset of progenitor cells that reside in fallopian tube supportive tissue, or stroma.

14 Mar 2025

New tissue engineering strategies for spinal cord injury repair

A recent study published in the journal Engineering delves into the application of tissue engineering in spinal cord injury (SCI) repair, presenting a comprehensive review of the latest research and potential treatment strategies.

12 Mar 2025

Strontium-enhanced exosomes show promise for osteoarthritis treatment

Temporomandibular joint osteoarthritis (TMJOA) is a debilitating condition that causes severe joint pain, restricted mobility, and progressive cartilage degradation.

24 Feb 2025

Novel MSC-based therapy provides hope for ocular GVHD treatment

Graft-versus-host disease (GVHD) is a common and severe complication that occurs after stem cell transplantation, where the donor's immune cells attack the recipient's tissues.

10 Feb 2025

Establishing common nomenclature for mitochondria transfer and transplantation

Most animal, plant and fungal cells contain organelles called mitochondria. These descendants of a primordial bacterial endosymbiont still preserve distinct genes and are known for their ability to create ATP as chemical energy.

27 Jan 2025

New insights into survival of breast cancer cells in the bone marrow

A study from researchers at the University of Michigan and the University of California San Diego has shed light on a previously poorly understood aspect of breast cancer recurrence: how cancer cells survive in bone marrow despite targeted therapies.

4 Dec 2024

Exploring the potential of MSCs in cancer therapy

A new review was published in Oncotarget's Volume 15 on November 22, 2024, entitled "Mesenchymal stem cells – the secret agents of cancer immunotherapy: Promises, challenges, and surprising twists."

4 Dec 2024

Overcoming challenges in developing cell therapies for heart disease

Pathways to new treatments for heart failure take time - as long as four decades for two now accepted therapies. So, new attempts to repair scar tissue in infarcted hearts using cells or cell products need more time to develop clinical therapies that can reduce risk of death from heart failure after a heart attack.

3 Dec 2024