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Research ushers in a new era of hope for patients with primary immune thrombocytopenia

More than half of patients in a Phase III clinical trial who received a limited course of the experimental monoclonal antibody ianalumab for primary immune thrombocytopenia (ITP), an autoimmune disorder that can cause life-threatening bleeding, were able to maintain safe platelet counts without serious bleeding episodes for at least one year.

9 Dec 2025

TXA reduces the need for blood transfusion in patients undergoing high-risk non-cardiac surgery

When hospitals were randomly assigned to treat patients undergoing higher-risk non-cardiac surgery with tranexamic acid (TXA) or a placebo, patients who received TXA needed significantly fewer blood transfusions and saw no increase in potentially life-threatening blood clots (thrombosis) after 90 days of follow-up, according to research presented at the 67th American Society of Hematology (ASH) Annual Meeting and Exposition.

9 Dec 2025

Laughing gas shows fast antidepressant effects in early clinical trials

A systematic review and meta-analysis in eBioMedicine shows that nitrous oxide can rapidly reduce depressive symptoms within hours, particularly at higher doses, but effects are short-lived after single treatments. Repeated dosing appears to extend and strengthen antidepressant benefits, although the current evidence is based on small, early-phase trials with limited long-term safety data.

8 Dec 2025

Lubiprostone shows signs of slowing kidney function decline in chronic kidney disease

In adults with stage IIIb–IV chronic kidney disease, the constipation drug lubiprostone did not reduce gut-derived uremic toxins but preserved creatinine-based kidney function over 24 weeks. The benefit was linked to microbiome remodeling, increased polyamine production, and improved mitochondrial function rather than toxin lowering.

8 Dec 2025

Calcium supplements do not prevent pre-eclampsia, large trials show no meaningful benefit

Despite long-standing recommendations, a major updated Cochrane review finds that calcium supplementation during pregnancy does not meaningfully reduce pre-eclampsia risk, prompting a rethink of how best to prevent hypertensive disorders in pregnancy.

7 Dec 2025

First new fibromyalgia drug in 15 years, Tonmya (cyclobenzaprine HCl) gains FDA approval and hits pharmacy shelves

In a milestone moment for chronic pain management, Tonix Pharmaceuticals announced on August 15, 2025, that its novel sublingual therapy Tonmya has received approval from the U.S. Food and Drug Administration (FDA) - marking the first new drug for Fibromyalgia in more than 15 years.

From Hanson Wade Group - Non-Opioid Pain Therapeutics Summit 5 Dec 2025

Higher PFAS levels reduce blood sugar improvements after teen bariatric surgery

A new USC study shows teens with higher blood levels of per- and polyfluoroalkyl substances (PFAS) measured before bariatric surgery had smaller improvements in blood sugar over five years, including fasting glucose and hemoglobin A1c (HbA1c), which measures average blood sugar levels over the past 60-90 days.

4 Dec 2025

University of Iowa research finds an effective therapy for rare kidney disease in children

A rare and life-threatening kidney disease in children finally has an effective therapy, thanks in large part to pioneering research and clinical leadership from University of Iowa Health Care Stead Family Children's Hospital.

4 Dec 2025

Settling the creatine safety debate

Research confirms creatine's safety, highlighting misinformation and low-quality supplements as primary concerns over cancer and kidney health risks.

3 Dec 2025

Calcium fails to prevent pre-eclampsia in pregnant women, study finds

An updated Cochrane review has found that calcium supplementation has no effect on pre-eclampsia, challenging long-held assumptions about the role of calcium in preventing hypertensive disorders in pregnancy.

3 Dec 2025

Shingles vaccine may benefit individuals already diagnosed with dementia, new study finds

An unusual public health policy in Wales may have produced the strongest evidence yet that a vaccine can reduce the risk of dementia.

2 Dec 2025

Antibiotics provide no relief for common colds

Researchers conclude that antibiotics should not be used to treat the common cold and acute purulent rhinitis.

28 Nov 2025

Experimental drug engasertib shows promise for treating inherited bleeding disorder

Hereditary hemorrhagic telangiectasia (HHT) is the second most common inherited bleeding disorder worldwide, affecting 1 in 3,800 persons.

26 Nov 2025

Metformin fails to improve insulin resistance in type 1 diabetes

Metformin treatment in type 1 diabetes lowers insulin dosage but does not improve insulin resistance, highlighting its complex role in diabetes management.

26 Nov 2025

Kimchi consumption strengthens antigen recognition and immune regulation

Amid concerns about the simultaneous spread of multiple respiratory diseases, such as colds and influenza, with the change of seasons in current times, a recent clinical study has scientifically proven that kimchi, a traditional Korean fermented food, enhances the function of human immune cells and maintains the balance of the immune system.

24 Nov 2025

Kennedy sharpens vaccine attacks, without scientific backing

As the federal government prepares for the next meeting of its Advisory Committee on Immunization Practices, Health and Human Services Secretary Robert F. Kennedy Jr. has intensified his attacks on aluminum vaccine components used in many shots to boost the body's immune response.

24 Nov 2025

Placebo News and Research

Research ushers in a new era of hope for patients with primary immune thrombocytopenia

TXA reduces the need for blood transfusion in patients undergoing high-risk non-cardiac surgery

Laughing gas shows fast antidepressant effects in early clinical trials

Lubiprostone shows signs of slowing kidney function decline in chronic kidney disease

Calcium supplements do not prevent pre-eclampsia, large trials show no meaningful benefit

First new fibromyalgia drug in 15 years, Tonmya (cyclobenzaprine HCl) gains FDA approval and hits pharmacy shelves

Higher PFAS levels reduce blood sugar improvements after teen bariatric surgery

University of Iowa research finds an effective therapy for rare kidney disease in children

Settling the creatine safety debate

Calcium fails to prevent pre-eclampsia in pregnant women, study finds

Shingles vaccine may benefit individuals already diagnosed with dementia, new study finds

Antibiotics provide no relief for common colds

Experimental drug engasertib shows promise for treating inherited bleeding disorder

Metformin fails to improve insulin resistance in type 1 diabetes

Kimchi consumption strengthens antigen recognition and immune regulation

Kennedy sharpens vaccine attacks, without scientific backing

New trial to test extended tranexamic acid use for faster ACL surgery recovery

Study shows gluten sensitivity is driven by gut–brain interactions rather than gluten

Study suggests cannabis may temporarily curb alcohol consumption

Oral GLP-1 pill shows strong weight loss and blood sugar benefits in adults with diabetes

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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