Ex Vivo News and Research

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High Throughput Identification and Quantification of Breast Cancer With NMR-Based Metabolomics

Breast cancer is the leading cause of cancer-related death among the female population globally, despite the ever-growing technology of early detection.

From Bruker BioSpin Group 30 Oct 2020

New method for producing FTVI enzyme can help improve cord blood transplants

A new way of producing an enzyme called fucosyltransferase VI (FTVI) in the lab could help enhance the therapeutic potential of cord blood transplants.

22 Oct 2020

Study determines mechanisms underlying abnormal development of nervous system in Hirschsprung disease

Ankush Gosain, MD, PhD, of Le Bonheur Children's Hospital and the University of Tennessee Health Science Center has focused his research on determining the mechanisms underlying abnormal development of the enteric nervous system in Hirschsprung disease.

14 Oct 2020

A new therapeutic approach for Epstein-Barr virus-associated tumors

A research team at LKS Faculty of Medicine, The University of Hong Kong (HKUMed) discovered that exosomes derived from Vδ2-T cells (Vδ2-T-Exos) can effectively control Epstein-Barr virus-associated tumours and induce T-cell anti-tumour immunity.

12 Oct 2020

Optimized low‐dose drug combinations to effectively treat colorectal cancer

Chemotherapy-based cancer treatment has distressing side effects for patients and increases the risk of developing resistance to the treatment.

6 Oct 2020

SARS-CoV-2 D614G variant enhances infectivity, replication and transmission

Researchers in the United States and Japan have conducted a study showing a common mutation in the spike protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) - the agent that causes coronavirus disease 2019 (COVD-19) - enhances the infectivity, replication, and early transmission of the virus.

30 Sep 2020

Negligible ACE2 expression in human beta-cells

Now, a new study published on the preprint server bioRxiv reports that even though the fatality rate is significantly higher in diabetics, there is no evidence that this is due to direct viral infection of pancreatic beta cells, which produce the key hormone in glucose homeostasis, namely insulin.

1 Sep 2020

Researchers develop new technique to improve cancer treatments

An innovative technique to improve cancer treatments using tumour biopsies less than 30 minutes after they're taken has been developed at The University of Queensland.

25 Aug 2020

Deciphering the largest CRISPR system

Professor Guillermo Montoya spoke to News-Medical on his research that involved visualizing the largest and most complex CRISPR system.

17 Aug 2020

Novel nanospectroscopy measures biomolecular changes induced by drugs in human cells

Synchrotron InfraRed Nanospectroscopy has been used for the first time to measure biomolecular changes induced by a drug (amiodarone) within human cells (macrophages) and localized at 100 nanometre scale, i.e. two orders of magnitude smaller than the IR wavelength used as probe.

17 Jul 2020

Human lungs rejected for transplant can be recovered using cross-circulation with pigs

A new experiment by researchers at the Columbia Engineering and Vanderbilt University may have the solution to this long-standing problem. The team revived and repaired the damaged lungs by cross-circulation support of the whole lungs outside the body using the circulatory system with that of a living pig.

14 Jul 2020

Severely injured donor lungs can be successfully recovered outside the body

Respiratory disease is the third leading cause of death worldwide, and lung transplantation is still the only cure for patients with end-stage lung disease.

13 Jul 2020

Molecular imaging reveals inter-organ communication between the heart and kidneys after heart attack

Whole body positron emission tomography (PET) has, for the first time, illustrated the existence of inter-organ communication between the heart and kidneys via the immune system following acute myocardial infarction, or heart attack.

13 Jul 2020

New drug discovery shows promise in fighting acute respiratory illnesses

A collaboration between the University of Toronto's Faculty of Dentistry and the National Jewish Health in Denver -- the top-ranked respiratory research hospital in the U.S. -- has yielded a new drug discovery that could be useful to combat inflammation of all varieties and shows promise in fighting acute respiratory illnesses such as COVID-19.

2 Jul 2020

Ex Vivo News and Research

High Throughput Identification and Quantification of Breast Cancer With NMR-Based Metabolomics

New method for producing FTVI enzyme can help improve cord blood transplants

Study determines mechanisms underlying abnormal development of nervous system in Hirschsprung disease

A new therapeutic approach for Epstein-Barr virus-associated tumors

Optimized low‐dose drug combinations to effectively treat colorectal cancer

SARS-CoV-2 D614G variant enhances infectivity, replication and transmission

Negligible ACE2 expression in human beta-cells

Researchers develop new technique to improve cancer treatments

Deciphering the largest CRISPR system

Novel nanospectroscopy measures biomolecular changes induced by drugs in human cells

Human lungs rejected for transplant can be recovered using cross-circulation with pigs

Severely injured donor lungs can be successfully recovered outside the body

Molecular imaging reveals inter-organ communication between the heart and kidneys after heart attack

New drug discovery shows promise in fighting acute respiratory illnesses

Scottish biotech Invizius seeks Series A funding for breakthrough in dialysis treatment

Study investigates potential of adoptive cell therapy in combination with checkpoint inhibitors

CSL Behring and Seattle Children's partner to develop gene therapies for primary immunodeficiency diseases

UZH researchers develop new X-ray contrast agent for high-resolution vascular imaging

Biologic drug can help treat contact dermatitis

Human to Labskin Skin Models for Dermatology Research

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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