Insulin News and Research

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Insulin is a hormone that is needed to convert glucose, starches and other food into energy needed for daily life. Insulin allows cells to use glucose for fuel and is secreted by beta cells in the islets of Langerhans. The release of insulin from the pancreas is stimulated by increased blood glucose, vagal nerve stimulation, and other factors. Insulin is obtained from various animals and available in a variety of preparations. Commercial insulin preparations differ in a number of ways, including differences in the animal species from which they are obtained; their purity, concentration, and solubility; and the time of onset and duration of their biologic action. An oral hypoglycemic agent is not a form of insulin therapy.

Ultra-processed foods linked to higher mortality in Black women with breast cancer

A study from Rutgers Cancer Institute researchers in eClinicalMedicine is the first to link ultra-processed foods to reduced survival in Black women with breast cancer.

18 Dec 2025

Gestational diabetes alters the placenta at the molecular level, study reveals

Gestational diabetes can cause a multitude of complications in the offspring, but to date, the reasons are incompletely understood.

18 Dec 2025

Scientists unravel how citrin deficiency can trigger fat buildup in the liver even in lean individuals

Scientists at City of Hope, one of the largest and most advanced cancer research and treatment organizations in the U.S. and a leading research center for diabetes and other life-threatening illnesses, have unraveled how citrin deficiency (CD), a rare genetic disorder that prevents the liver from converting food into energy efficiently, can trigger fat buildup in the liver - even in lean individuals.

18 Dec 2025

Strong heart health lowers long-term death risk in cancer survivors

Higher Life’s Simple 7 cardiovascular health scores were associated with lower long-term all-cause and cancer mortality in cancer survivors from a large Italian cohort. Inflammation, resting heart rate, and vitamin D statistically explained a substantial share of these associations, supporting shared cardiometabolic pathways across cancer and cardiovascular disease.

17 Dec 2025

Intermittent fasting edges daily calorie cuts for blood pressure and long-term cardiovascular risk estimates

In a real-world registry study of adults with overweight or obesity, 5:2 intermittent fasting and daily calorie restriction both improved blood pressure over 12 weeks. Intermittent fasting produced modestly greater reductions in systolic and pulse pressure and a larger drop in BMI-based 30-year cardiovascular risk scores, without superior lipid or glycaemic effects.

17 Dec 2025

How Traditional Chinese Medicine may reshape the gut microbiome to ease insulin resistance in PCOS

This review synthesizes evidence that gut microbiota dysbiosis contributes to insulin resistance and symptom severity in polycystic ovary syndrome through impaired barrier function, inflammation, and altered microbial metabolites. It evaluates how Traditional Chinese Medicine may modulate these pathways while highlighting major gaps in clinical validation, safety, and standardization.

16 Dec 2025

Tau biology expands beyond microtubules to neurodegeneration, metabolism and mental illness

An Thought Leaders Invited Review published today in Genomic Psychiatry by Dr. Peng Lei and colleagues presents a sweeping synthesis of tau protein research that fundamentally reframes our understanding of this molecule's dual identity.

16 Dec 2025

High fructose intake increases fatty liver risk

Excessive fructose intake from soft drinks is linked to liver damage and NAFLD. Lifestyle modifications are essential for effective prevention and treatment.

16 Dec 2025

What drinking kefir really does to your gut and oral microbiome

The impact of kefir on gut and oral microbiomes shows promise, but inconsistent findings and study limitations call for more rigorous scientific investigation.

15 Dec 2025

Swapping high-carb snacks for tree nuts cuts food cravings in young adults at metabolic risk

Daily replacement of typical high-carbohydrate snacks with mixed tree nuts for 16 weeks reduced cravings for sweets and fast foods in young adults with early metabolic syndrome risk. This dietary swap improved overall diet quality, measured by the Healthy Eating Index, without increasing body weight or altering short-term glycaemic markers.

14 Dec 2025

Single-cell RNA-seq reveals FBLN7's role in adipose tissue fibrosis

Fibrosis, resulting from excess extracellular matrix (ECM) deposition, is a feature of adipose tissue (AT) dysfunction and obesity-related insulin resistance.

13 Dec 2025

What happens to your body when you eat takeaway food too often?

This study of 8,556 US adults shows that frequent takeaway food consumption is associated with a higher energy-adjusted Dietary Inflammatory Index and adverse cardiometabolic markers. The findings suggest that reducing takeaway intake and lowering dietary inflammatory potential may improve long-term cardiometabolic health.

11 Dec 2025

What happens to your body during an ultramarathon? New study reveals key metabolic changes

This study tracked ultramarathon runners across 100 km, 160.9 km, and 230 km events to examine real-world metabolic, hormonal, and muscle stress responses. Severe energy deficits, muscle damage, and heterogeneous hormonal shifts were observed, with the greatest strain seen in the 230 km distance.

10 Dec 2025

Study elucidates novel mitochondrial mechanisms underlying anti-aging and longevity

As life expectancy continues to climb globally, the focus of many people has moved from longevity alone to living in good health.

10 Dec 2025

Family history of cardiometabolic disease linked to early heart damage in adolescents

A new study among more than 1,500 British adolescents is the first in the world to assess the association between familial cardiometabolic diseases and the offspring's risk of premature heart damage by early adulthood.

10 Dec 2025

Filtered coffee shows a causal link to healthier HbA1c levels

Genetically predicted filtered coffee consumption is causally associated with lower HbA1c levels, while other coffee preparation methods show no such benefit. This effect appears to be partly mediated by increases in propionate producing gut bacteria, particularly Veillonella.

10 Dec 2025

Sterilized fermented beverage targets obesity and type 2 diabetes pathways in computational study

Researchers profiled a terminally sterilized probiotic-fermented MFH beverage and identified aporphine alkaloids and flavonoids with favorable predicted ADMET properties. Integrated network pharmacology, molecular docking, and 100-ns MD simulations suggest multi-target engagement of metabolic-inflammatory pathways relevant to obesity and type 2 diabetes.

9 Dec 2025

Genetic risk score can guide early screening for type 1 diabetes

A test using genetics to predict who is at the highest risk of developing type 1 diabetes could one day be applied to largescale health studies, to identify adults who could benefit from new drugs, new research shows.

9 Dec 2025

Gut microbe metabolite TMA improves blood sugar by shutting down a key inflammatory switch

Researchers identified trimethylamine (TMA) as a gut microbe–derived metabolite that directly inhibits IRAK4 to reduce metabolic inflammation and improve glycaemic control in high-fat-diet-fed mice. Choline-driven increases in TMA production replicated these benefits, revealing a host–microbe signaling axis with therapeutic potential for obesity-associated insulin resistance.

9 Dec 2025

Brain function discovery helps explain why childhood adversity raises metabolic disease risk in women

McGill University researchers have identified a brain function that helps explain why childhood stress raises metabolic health risks for some women later in life.

9 Dec 2025

Insulin News and Research

Further Reading

Ultra-processed foods linked to higher mortality in Black women with breast cancer

Gestational diabetes alters the placenta at the molecular level, study reveals

Scientists unravel how citrin deficiency can trigger fat buildup in the liver even in lean individuals

Strong heart health lowers long-term death risk in cancer survivors

Intermittent fasting edges daily calorie cuts for blood pressure and long-term cardiovascular risk estimates

How Traditional Chinese Medicine may reshape the gut microbiome to ease insulin resistance in PCOS

Tau biology expands beyond microtubules to neurodegeneration, metabolism and mental illness

High fructose intake increases fatty liver risk

What drinking kefir really does to your gut and oral microbiome

Swapping high-carb snacks for tree nuts cuts food cravings in young adults at metabolic risk

Single-cell RNA-seq reveals FBLN7's role in adipose tissue fibrosis

What happens to your body when you eat takeaway food too often?

What happens to your body during an ultramarathon? New study reveals key metabolic changes

Study elucidates novel mitochondrial mechanisms underlying anti-aging and longevity

Family history of cardiometabolic disease linked to early heart damage in adolescents

Filtered coffee shows a causal link to healthier HbA1c levels

Sterilized fermented beverage targets obesity and type 2 diabetes pathways in computational study

Genetic risk score can guide early screening for type 1 diabetes

Gut microbe metabolite TMA improves blood sugar by shutting down a key inflammatory switch

Brain function discovery helps explain why childhood adversity raises metabolic disease risk in women

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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