Insulin News and Research

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Insulin is a hormone that is needed to convert glucose, starches and other food into energy needed for daily life. Insulin allows cells to use glucose for fuel and is secreted by beta cells in the islets of Langerhans. The release of insulin from the pancreas is stimulated by increased blood glucose, vagal nerve stimulation, and other factors. Insulin is obtained from various animals and available in a variety of preparations. Commercial insulin preparations differ in a number of ways, including differences in the animal species from which they are obtained; their purity, concentration, and solubility; and the time of onset and duration of their biologic action. An oral hypoglycemic agent is not a form of insulin therapy.

Cyborg transplants may advance cell-based therapies for diabetes

A new electronic implant system can help lab‑grown pancreatic cells mature and function properly, potentially providing a basis for novel, cell-based therapies for diabetes.

19 Feb 2026

Gut microbiome may shape response to GLP-1 drugs, new review suggests

This review examines how GLP-1 receptor agonists and the gut microbiome influence one another through bile acid signaling, short-chain fatty acids, and inflammatory pathways. It explores how microbial composition may shape treatment response and highlights the need for controlled human studies to enable microbiome-informed precision therapy.

19 Feb 2026

Gut bacteria patterns help predict insulin resistance in type 2 diabetes, study finds

Researchers used 16S rRNA sequencing and machine learning to identify gut microbiome patterns associated with insulin resistance severity in people with type 2 diabetes. XGBoost models showed that specific bacterial genera, including Bacteroides and Faecalibacterium, help distinguish individuals with higher insulin resistance from healthy controls.

19 Feb 2026

New cellular discovery shows promise for treating painful lymphedema

A newly discovered cellular mechanism shows promise for treating painful lymphedema.

18 Feb 2026

Researchers identify a genetic brake for the formation of blood vessels in muscles

In an international study, researchers at Lund University in Sweden have identified a gene variant that controls the body's capability to form new blood vessels in muscles – a mechanism that affects physical performance, health and recovery.

18 Feb 2026

Can GLP-1 drugs slow neurodegeneration? New review finds promising signals but limited clinical proof

This review examines how GLP-1 receptor agonists may influence neurodegenerative disease biology through metabolic, inflammatory, mitochondrial, and proteostasis pathways. Evidence from mechanistic, preclinical, and early clinical studies suggests potential neuroprotective effects, but definitive disease-modifying benefit remains unproven.

17 Feb 2026

Does intermittent fasting help you lose more weight? Evidence review finds no clear advantage

A Cochrane systematic review of 22 randomized trials involving 1,995 adults with overweight or obesity found intermittent fasting produces weight loss comparable to traditional calorie restriction. Evidence suggests little additional benefit for quality of life or adverse effects, with overall certainty ranging from low to moderate and long-term effects still unclear.

17 Feb 2026

Harnessing AI to optimize the development of new protein manufacturing processes

Industrial yeasts are a powerhouse of protein production, used to manufacture vaccines, biopharmaceuticals, and other useful compounds.

17 Feb 2026

Study links microbe-rich diets with better insulin and cholesterol markers

This exploratory Australian study developed a database to estimate live microbe content in foods and examined associations with cardiometabolic health indicators in adults. Higher intake of foods estimated to contain live microbes was linked with favourable markers such as higher HDL cholesterol and lower BMI, insulin, and waist circumference, although causality cannot be inferred.

16 Feb 2026

Do cocoa flavanols influence heart and fatty liver risk factors?

A recent Nutrients review examined whether cocoa-rich dark chocolate influences cardiovascular and metabolic dysfunction-associated steatotic liver disease risk factors through antioxidant, anti-inflammatory, and endothelial effects. Evidence suggests modest improvements in biomarkers, but most data come from short-term studies, so definitive clinical benefits remain unproven.

16 Feb 2026

Machine learning model demonstrates insulin resistance as a risk factor for 12 types of cancer

Insulin resistance - when the body doesn't properly respond to insulin, a hormone that helps control blood glucose levels - is one of the fundamental causes of diabetes.

16 Feb 2026

Big breakfast study reveals protein curbs appetite but fiber delivers stronger gut microbiome benefits

A randomized crossover weight loss trial in adults with overweight or obesity found that higher protein big breakfasts improved satiety, while higher fibre breakfasts produced slightly greater weight loss and more favourable gut microbiota markers. Both diets improved metabolic biomarkers, but microbiota changes reflected surrogate gut health indicators rather than direct clinical outcomes.

15 Feb 2026

Role of food nutrients in reducing oxidative stress linked to micro- and nanoplastics

This narrative review examines how micro- and nanoplastics may contribute to oxidative stress, inflammation, and metabolic dysfunction, including potential links with diabetes. It highlights plant-derived nutrients that activate the Nrf2 pathway as a possible strategy to enhance cellular stress resilience, although most evidence remains preclinical.

15 Feb 2026

Ozempic users continue treatment when weight loss works despite side effects

A study on Ozempic for weight loss reveals user satisfaction is driven by efficacy, despite common gastrointestinal side effects impacting treatment adherence.

13 Feb 2026

Magnesium lower fasting blood sugar in older adults

Magnesium boosts fasting glucose control in older adults with deficiency, but preventing diabetes progression may need more than just mineral correction.

13 Feb 2026

Boosting good immune cells can help fight insulin resistance and diabetes

Scientists at the University of Pittsburgh School of Medicine discovered a surprising new way the body can fight insulin resistance and diabetes – by boosting a special type of "good" immune cell in fat tissue.

12 Feb 2026

Aligning overnight fasting with sleep improves heart health

A new Northwestern Medicine study has personalized overnight fasting by aligning it with individuals' circadian sleep-wake rhythm - an important regulator of cardiovascular and metabolic function - without changing their caloric intake.

12 Feb 2026

Weight loss drug tirzepatide may lower the risk of diabetic retinopathy

The popular diabetes and weight loss medication tirzepatide (brand name Mounjaro or Zepbound) may lower the risk of diabetic retinopathy, a leading cause of vision loss, according to Weill Cornell Medicine investigators.

11 Feb 2026

Breastfeeding and healthy infant diets may help lower obesity risk by age nine

nationwide Icelandic cohort study found that better alignment with infant nutrition guidelines was associated with lower odds of obesity at ages 6 and 9 years. Associations were inconsistent at younger ages, highlighting the complex and multifactorial nature of childhood weight outcomes.

11 Feb 2026

Review links betel nut addiction to cancer, heart disease, and metabolic risks

This review examines the epidemiology, health risks, neurobiological mechanisms, and emerging treatments related to betel nut addiction worldwide. It highlights strong links with oral cancer, cardiometabolic disease, and addiction pathways while noting limited established therapies and the need for coordinated public health strategies.

11 Feb 2026

Insulin News and Research

Further Reading

Cyborg transplants may advance cell-based therapies for diabetes

Gut microbiome may shape response to GLP-1 drugs, new review suggests

Gut bacteria patterns help predict insulin resistance in type 2 diabetes, study finds

New cellular discovery shows promise for treating painful lymphedema

Researchers identify a genetic brake for the formation of blood vessels in muscles

Can GLP-1 drugs slow neurodegeneration? New review finds promising signals but limited clinical proof

Does intermittent fasting help you lose more weight? Evidence review finds no clear advantage

Harnessing AI to optimize the development of new protein manufacturing processes

Study links microbe-rich diets with better insulin and cholesterol markers

Do cocoa flavanols influence heart and fatty liver risk factors?

Machine learning model demonstrates insulin resistance as a risk factor for 12 types of cancer

Big breakfast study reveals protein curbs appetite but fiber delivers stronger gut microbiome benefits

Role of food nutrients in reducing oxidative stress linked to micro- and nanoplastics

Ozempic users continue treatment when weight loss works despite side effects

Magnesium lower fasting blood sugar in older adults

Boosting good immune cells can help fight insulin resistance and diabetes

Aligning overnight fasting with sleep improves heart health

Weight loss drug tirzepatide may lower the risk of diabetic retinopathy

Breastfeeding and healthy infant diets may help lower obesity risk by age nine

Review links betel nut addiction to cancer, heart disease, and metabolic risks

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