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Surprising new function of immune cells uncovered: Excess weight loss prevention

Researchers at the University of California San Diego School of Medicine have uncovered a surprising new function for immune cells: preventing excess weight loss.

10 Dec 2025

Next-generation oral SERD therapy lowers the risk of breast cancer recurrence

In an international study led by UCLA, researchers have shown that giredestrant, a next-generation oral selective estrogen receptor antagonist and degrader (SERD), when given as an adjuvant therapy for early-stage (1-3) hormone receptor (HR)-positive, HER2-negative breast cancer, significantly lowered the risk of the disease returning when compared with standard hormone therapies long considered the backbone of treatment.

10 Dec 2025

Machine learning models can help diagnose ALS earlier from a blood sample

Using machine learning models, researchers at Michigan Medicine have identified a potential way to diagnose amyotrophic lateral sclerosis, or ALS, earlier from a blood sample, a study suggests.

10 Dec 2025

Young adolescents participating in organized sports less likely to show oppositional-defiant behavior

Young adolescents, especially boys, who participated in organized sports between ages 6 and 10 are less likely to defy their parents, teachers and other authority figures, a new study by researchers in Canada and Italy suggests.

10 Dec 2025

Researchers map how brain networks differ in individuals at high clinical risk for psychosis

Researchers from the Yong Loo Lin School of Medicine, National University of Singapore (NUS Medicine), and NHG Health's Institute of Mental Health (IMH) have mapped how brain networks differ in individuals at Clinical High Risk (CHR) for psychosis, providing a new perspective on the mechanisms underlying the disease onset.

10 Dec 2025

$Tec-Dara could represent a new standard of care for relapsed or refractory multiple myeloma$

Tec-Dara could represent a new standard of care for relapsed or refractory multiple myeloma

Patients with relapsed or refractory (R/R) multiple myeloma who received a combination of teclistamab, a bispecific monoclonal antibody, and daratumumab, a CD38-directed monoclonal antibody, were 83% more likely to be alive without disease progression compared with those who received standard second-line therapies at a median of nearly 35 months of follow-up, according to the results of a new trial presented at the 67th American Society of Hematology (ASH) Annual Meeting and Exposition.

10 Dec 2025

Sterilized fermented beverage targets obesity and type 2 diabetes pathways in computational study

Researchers profiled a terminally sterilized probiotic-fermented MFH beverage and identified aporphine alkaloids and flavonoids with favorable predicted ADMET properties. Integrated network pharmacology, molecular docking, and 100-ns MD simulations suggest multi-target engagement of metabolic-inflammatory pathways relevant to obesity and type 2 diabetes.

9 Dec 2025

Researchers discover new biomarker of "complicated" mild- to severe-pediatric traumatic brain injury

Researchers at the University of Pittsburgh and UPMC Children's Hospital of Pittsburgh discovered a promising new biomarker of "complicated" mild- to severe-pediatric traumatic brain injury, or TBI.

9 Dec 2025

State-funded multidisciplinary model improves care for adults with neurodevelopmental disorders

Adults with autism spectrum disorder (ASD) and other neurodevelopmental disorders (NDDs) often lose access to specialized care once they age out of pediatric services.

9 Dec 2025

Mammary glands of domesticated livestock and humans could harbor avian influenza

An ongoing outbreak of highly pathogenic avian influenza has affected more than 184 million domestic poultry since 2022 and, since making the leap to dairy cattle in spring 2024, more than 1,000 milking cow herds.

9 Dec 2025

Global study reveals massive hidden health burden from violence against women and children

Sexual violence against children and intimate partner violence against women are two of the most devastating yet persistently underrecognized global health challenges and rank among the top risks for mortality and morbidity worldwide, according to research published in The Lancet today.

9 Dec 2025

Study shows widespread use of corridors and waiting rooms for emergency care

At any one time, nearly 1 in 5 emergency department patients in the UK is being cared for in corridors, waiting rooms, and other non-standard 'overflow' spaces-an approach known as escalation area care-suggest the results of a large observational study, published online in Emergency Medicine Journal.

9 Dec 2025

Landmark RSI trial reshapes sedative selection for emergency airway management

Doctors treating seriously ill patients in an emergency setting may want to give the sedative etomidate, rather than ketamine, while placing a breathing tube, according to a randomized trial published in the New England Journal of Medicine.

9 Dec 2025

Study explains why mpox cases can appear weeks after exposure

Mpox virus clade Ib shows a longer and more variable incubation period than previously characterized clades, with symptom onset extending well beyond 21 days in a substantial minority of cases. Incubation varies by transmission route, with shorter intervals after sexual exposure and longer periods following nonsexual community transmission, raising implications for surveillance and postexposure guidance.

9 Dec 2025

Small molecule discovery could open the door to new class of treatments for hard-to-treat cancers

Researchers at the UCLA Health Jonsson Comprehensive Cancer Center have identified a small molecule that can inhibit a cancer-driving protein long considered impossible to target with drugs - a discovery that could open the door to a new class of treatments for leukemia and other hard-to-treat cancers.

9 Dec 2025

People exposed to Agent Orange face higher risk of developing myelodysplastic syndrome

A new national study shows for the first time that people exposed to Agent Orange face a higher risk of developing myelodysplastic syndrome (MDS), tend to develop it earlier, and often have more aggressive disease that is more likely to progress to acute myeloid leukemia.

9 Dec 2025

WSU researchers discover how a neural circuit drives relapse after opioid use

Washington State University researchers have discovered how a neural circuit – or a connection between two brain regions – drives relapse after opioid use, a finding that could lead to more effective treatments for opioid use disorders.

9 Dec 2025

Research ushers in a new era of hope for patients with primary immune thrombocytopenia

More than half of patients in a Phase III clinical trial who received a limited course of the experimental monoclonal antibody ianalumab for primary immune thrombocytopenia (ITP), an autoimmune disorder that can cause life-threatening bleeding, were able to maintain safe platelet counts without serious bleeding episodes for at least one year.

9 Dec 2025

Study uncovers how the body's bile acids bind to block C. diff's most dangerous toxin

In a major step towards a precision therapy for Clostridioides difficile (C. diff) infection, researchers at The Hospital for Sick Children (SickKids) have uncovered how the body's bile acids bind to block C. diff's most dangerous toxin.

9 Dec 2025

Most people wary of AI for health diagnosis but optimistic for cancer detection

New research on public attitudes toward AI indicates that most people are reluctant to let ChatGPT and other AI tools diagnose their health condition, but see promise in technologies that use AI to help diagnose cancer.

9 Dec 2025

Medicine News and Research

Surprising new function of immune cells uncovered: Excess weight loss prevention

Next-generation oral SERD therapy lowers the risk of breast cancer recurrence

Machine learning models can help diagnose ALS earlier from a blood sample

Young adolescents participating in organized sports less likely to show oppositional-defiant behavior

Researchers map how brain networks differ in individuals at high clinical risk for psychosis

Tec-Dara could represent a new standard of care for relapsed or refractory multiple myeloma

Sterilized fermented beverage targets obesity and type 2 diabetes pathways in computational study

Researchers discover new biomarker of "complicated" mild- to severe-pediatric traumatic brain injury

State-funded multidisciplinary model improves care for adults with neurodevelopmental disorders

Mammary glands of domesticated livestock and humans could harbor avian influenza

Global study reveals massive hidden health burden from violence against women and children

Study shows widespread use of corridors and waiting rooms for emergency care

Landmark RSI trial reshapes sedative selection for emergency airway management

Study explains why mpox cases can appear weeks after exposure

Small molecule discovery could open the door to new class of treatments for hard-to-treat cancers

People exposed to Agent Orange face higher risk of developing myelodysplastic syndrome

WSU researchers discover how a neural circuit drives relapse after opioid use

Research ushers in a new era of hope for patients with primary immune thrombocytopenia

Study uncovers how the body's bile acids bind to block C. diff's most dangerous toxin

Most people wary of AI for health diagnosis but optimistic for cancer detection

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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