Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

GB Sciences announces preclinical results of promising formulations for Parkinson's disease

GB Sciences, Inc. announced significant preclinical results for their Parkinson's disease ("PD") formulations from the midterm report for their preclinical study being performed by Dr. Lee Ellis of the National Research Council in Halifax, Nova Scotia, CANADA.

22 Dec 2019

Jefferson researcher probes kidney cancer's genes for interactions with p53 pathway

p53 is the most famous cancer gene, not least because it's involved in causing over 50% of all cancers. When a cell loses its p53 gene -- when the gene becomes mutated -- it unleashes many processes that lead to the uncontrolled cell growth and refusal to die, which are hallmarks of cancer growth.

20 Dec 2019

Fibroblasts involved in healing wounds play a devastating role in breast cancer development

The connective tissue cells known as fibroblasts are vitally important for our recovery from injury. Sensing tissue damage, they gravitate to the site of a wound, instigating an inflammatory response that mends damaged tissue.

19 Dec 2019

Connection between herpes virus and Alzheimer’s refuted

A new study has shown that unlike previous claims, there is no association between getting herpes infections and developing Alzheimer’s disease. The study from the researchers at the Baylor College of Medicine was titled, “Are HHV-6A and HHV-7 really more abundant in Alzheimer’s disease?” and was published in the journal Neuron.

19 Dec 2019

Study reveals new role for a triple-negative breast cancer target

Unlike almost every other organ, the mammary gland does not develop until after birth. And it's unusually dynamic, shape-shifting during menstrual cycles, puberty, pregnancy, and lactation.

19 Dec 2019

A new book on ovarian cancer

An opening discussion of contemporary management of this disease presents commentary on surgery and clinical trials: neoadjuvant, dose-dense, and heated intraperitoneal chemotherapy (HIPEC}, as well as immunotherapy, vaccine therapy, emerging therapies.

18 Dec 2019

Suppressing MSUT2 gene may protect people from Alzheimer’s disease

In the wake of recent disappointments over clinical trials targeting amyloid plaque build-up in Alzheimer's disease, researchers are focusing more attention on misfolded tau protein, another culprit in brain diseases that cause dementia.

18 Dec 2019

Olympus and Ultivue Announce Comarketing Agreement for Leading-Edge Fluorescent Multiplexing Solution

Olympus SLIDEVIEW™ VS200 slide scanner and Ultivue UltiMapper™ reagents meet the changing needs of the scientific community

From Evident Corporation - Life Sciences 18 Dec 2019

AI identifies previously unknown features relevant to cancer prognosis

Artificial intelligence technology developed by the RIKEN Center for Advanced Intelligence Project in Japan has successfully found features in pathology images from human cancer patients, without annotation, that could be understood by human doctors.

18 Dec 2019

Study: Blocking IL1α protein decreases severity of inflammation in Crohn's disease

Investigators at the Case Western Reserve University School of Medicine discovered that blocking interleukin-1α (IL1α), a protein that controls inflammation in the gut, markedly decreases the severity of intestinal inflammation in a mouse model of Crohn's disease (CD).

17 Dec 2019

Seafood consumption and mercury concentrations in vulnerable coastal Florida population

Mercury contamination of the marine environment is a global public health concern. Human exposure occurs primarily by eating seafood, especially large predatory fish such as swordfish and albacore tuna.

16 Dec 2019

Molecular subtyping of bladder tumors outperformed by standard pathology tests

While trying to develop a comparatively easy, inexpensive way to give physicians and their patients with bladder cancer a better idea of likely outcome and best treatment options, scientists found that sophisticated new subtyping techniques designed to do this provide no better information than long-standing pathology tests.

14 Dec 2019

Continuous RCB index is an accurate and reliable tool to assess breast cancer prognosis

Researchers from The University of Texas MD Anderson Cancer Center today reported results from a pooled analysis of more than 5,100 breast cancer patients that found residual cancer burden continuous index and classification were independently and strongly prognostic for all breast cancer phenotypes.

13 Dec 2019

Study suggests antiarrhythmic drug as potential treatment for pulmonary arterial hypertension

High blood pressure in the lungs, known as pulmonary arterial hypertension (PAH), is a potentially fatal disease caused by obstruction of blood flow in the lungs.

12 Dec 2019

Experimental Alzheimer’s drugs show promise

Researchers from Salk have found that two experimental drugs named CMS121 and J147 may improve memory functions and reduce the progression of memory decline and brain degeneration in mice models of Alzheimer’s disease (AD). The researchers published their work in the latest issue of the journal eLife. The study was titled, “Elevating acetyl-CoA levels reduces aspects of brain aging.”

11 Dec 2019

Scientists evaluate mouse models used for developing new treatments for Huntington's disease

Huntington's disease (HD) is an incurable and fatal hereditary disease. Developing disease-modifying drugs to treat patients with HD depends on studying them in animal models. Scientists evaluated the mouse models used for developing new treatments for mood disorders in HD and recommended which of these models are most relevant to their studies.

11 Dec 2019

Study could help improve GENUS to become a therapeutic approach for Alzheimer's disease

The sweeping extent to which increasing 40Hz "gamma" rhythm power in the brain can affect the pathology and symptoms of Alzheimer's disease in mouse models has been surprising, even to the MIT neuroscientists who've pioneered the idea. So surprising, in fact, they can't yet explain why it happens.

11 Dec 2019

Research suggests new strategies for developing psoriasis therapies

Psoriasis is a skin disorder that affects at least 100 million individuals worldwide. Its economic impact is more than $10 billion annually in the U.S. alone.

11 Dec 2019

Study provides most detailed classification of acute myeloid leukemia, myelodysplastic syndrome

Results from a study conducted by St. Jude Children's Research Hospital and the Munich Leukemia Laboratory were presented today as a late-breaking abstract at the American Society of Hematology annual meeting. The study integrates genomic and transcriptomic sequencing to provide the most detailed classification of acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) to date.

10 Dec 2019

New software tool uses AI to recognize cancer cells from digital pathology images

UT Southwestern researchers have developed a software tool that uses artificial intelligence to recognize cancer cells from digital pathology images - giving clinicians a powerful way of predicting patient outcomes.

9 Dec 2019

Pathology News and Research

Further Reading

GB Sciences announces preclinical results of promising formulations for Parkinson's disease

Jefferson researcher probes kidney cancer's genes for interactions with p53 pathway

Fibroblasts involved in healing wounds play a devastating role in breast cancer development

Connection between herpes virus and Alzheimer’s refuted

Study reveals new role for a triple-negative breast cancer target

A new book on ovarian cancer

Suppressing MSUT2 gene may protect people from Alzheimer’s disease

Olympus and Ultivue Announce Comarketing Agreement for Leading-Edge Fluorescent Multiplexing Solution

AI identifies previously unknown features relevant to cancer prognosis

Study: Blocking IL1α protein decreases severity of inflammation in Crohn's disease

Seafood consumption and mercury concentrations in vulnerable coastal Florida population

Molecular subtyping of bladder tumors outperformed by standard pathology tests

Continuous RCB index is an accurate and reliable tool to assess breast cancer prognosis

Study suggests antiarrhythmic drug as potential treatment for pulmonary arterial hypertension

Experimental Alzheimer’s drugs show promise

Scientists evaluate mouse models used for developing new treatments for Huntington's disease

Study could help improve GENUS to become a therapeutic approach for Alzheimer's disease

Research suggests new strategies for developing psoriasis therapies

Study provides most detailed classification of acute myeloid leukemia, myelodysplastic syndrome

New software tool uses AI to recognize cancer cells from digital pathology images

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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