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SN101 iPSC-derived therapy relieves chronic pain and preserves joints

SereNeuro Therapeutics, a preclinical biotechnology company developing non-opioid pain therapies, unveiled new data today on a novel approach to chronic pain management and joint tissue preservation.

12 Dec 2025

Metabolic imaging enables early response prediction in bone-dominant metastatic breast cancer

A prospective, multicenter cancer clinical trial by the ECOG-ACRIN Cancer Research Group (ECOG-ACRIN) has validated an improved method for predicting treatment benefits in patients with hormone receptor-positive (HR+) metastatic breast cancer that has spread primarily or exclusively to the bones.

12 Dec 2025

Exclusive licensing agreement accelerates PHD inhibitor development for anemia in CKD patients

Insilico Medicine ("Insilico"), a clinical-stage generative artificial intelligence (AI)-driven drug discovery company, and TaiGen Biotechnology, a listed discovery-based and market-focused pharmaceutical company, as well as TaiGen Biopharmaceuticals, its wholly-owned Beijing subsidiary (both referred to as "TaiGen"), today announced an exclusive pipeline out-licensing collaboration.

12 Dec 2025

Researchers identify chromatin accessibility changes driving stem cell transformation in MDS

Over the past few decades, advances in hematology have illuminated how a delicate balance between stem cell self-renewal and differentiation sustains healthy blood formation.

12 Dec 2025

Plant-based diets support healthy growth when properly planned for children

Vegetarian and vegan diets can support healthy growth when carefully planned with appropriate supplementation, finds a major new meta-analysis – the most comprehensive study to-date of plant-based diets in children.

12 Dec 2025

Study offers insight into how coffee and tea intake may influence bone health in older women

A new study from Flinders University offers insight into how two of the world's most popular beverages, coffee and tea, may influence bone health in older women.

11 Dec 2025

Researchers discover the enzyme responsible for chromothripsis in cancer

University of California San Diego researchers have discovered the enzyme responsible for chromothripsis, a process in which a single chromosome is shattered into pieces and rearranged in a scrambled order, allowing cancer cells to rapidly evolve and become resistant to treatment.

11 Dec 2025

Expanded donor matching makes stem cell transplants accessible

For years, the search for a stem cell donor has felt like a quest for a rare key-one that fits a lock with eight intricate tumblers, each representing a genetic marker.

10 Dec 2025

Antibody therapy clears residual multiple myeloma in early trial

Treatment with an immune and cancer cell-targeting antibody therapy eradicates residual traces of the blood cell cancer multiple myeloma, according to interim results from a clinical trial conducted by researchers at Sylvester Comprehensive Cancer Center, part of the University of Miami Miller School of Medicine.

10 Dec 2025

Why the form of vitamin B12 you take may matter more than your intake

This comprehensive review examines vitamin B12 absorption, physiological roles, deficiency states, and dietary sources, with particular attention to differences between natural and synthetic forms. The authors conclude that while all B12 forms raise circulating levels, methylcobalamin may offer advantages in specific clinical contexts, especially where absorption or metabolic conversion is impaired.

10 Dec 2025

Two ongoing studies show promise of pivekimab sunirine in treating aggressive blood cancers

Researchers from The University of Texas MD Anderson Cancer Center presented promising new data from two ongoing studies of pivekimab sunirine (PVEK), an antibody-drug conjugate targeting CD123, in treating two aggressive blood cancers at the 67th American Society of Hematology (ASH) Annual Meeting and Exposition.

10 Dec 2025

Pirtobrutinib shows superior outcomes compared to common first-line combination treatment for CLL/SLL

In a new trial, the Bruton tyrosine kinase (BTK) inhibitor pirtobrutinib increased the rate of survival without disease progression and was well tolerated with a more favorable safety profile when compared with bendamustine plus rituximab (BR) in patients with previously untreated chronic lymphocytic leukemia (CLL) and small lymphocytic lymphoma (SLL).

10 Dec 2025

People exposed to Agent Orange face higher risk of developing myelodysplastic syndrome

A new national study shows for the first time that people exposed to Agent Orange face a higher risk of developing myelodysplastic syndrome (MDS), tend to develop it earlier, and often have more aggressive disease that is more likely to progress to acute myeloid leukemia.

9 Dec 2025

Routine blood test may flag hidden osteoporosis risk, study finds

A large hospital-based cross-sectional study examined whether routinely measured serum alkaline phosphatase can indicate osteoporosis risk in adults undergoing health checks. Higher ALP levels, even within the normal range, were associated with greater osteoporosis likelihood, particularly in younger, female, and metabolically healthy individuals.

9 Dec 2025

Genome-edited immune cell therapy shows promise for treating aggressive blood cancer

A groundbreaking new treatment using genome-edited immune cells, developed by scientists at UCL (University College London) and Great Ormond Street Hospital (GOSH), has shown promising results in helping children and adults fight a rare and aggressive form of blood cancer called T-cell acute lymphoblastic leukemia (T-ALL).

8 Dec 2025

Most T-cell/histocyte-rich large B-cell lymphoma patients can safely receive a less toxic treatment

Most patients with a rare and aggressive form of large B-cell lymphoma can safely receive a less toxic treatment than the intensive chemotherapy often used, according to new research from Sylvester Comprehensive Cancer Center, part of the University of Miami Miller School of Medicine.

8 Dec 2025

Why female athletes need injury prevention rules built for women, not men

This International Olympic Committee consensus synthesised evidence from over 600 studies to develop 56 injury prevention recommendations tailored to female, woman and girl athletes. It concludes that reducing injury risk requires a whole sports system approach that integrates training, policy, environment and culture, not exercise alone.

8 Dec 2025

Poor dietary iron weakens lung memory T cells after flu infection

Dietary iron deficiency in mice alters lung T cell activation during influenza infection and leads to memory T cells that are present in normal or increased numbers but have impaired antiviral cytokine responses. These functional deficits are most pronounced in lung CD8-positive memory T cells and persist even under optimal recall conditions.

8 Dec 2025

Novel wireless device uses light to send information directly to the brain

In a new leap for neurobiology and bioelectronics, Northwestern University scientists have developed a wireless device that uses light to send information directly to the brain - bypassing the body's natural sensory pathways.

8 Dec 2025

A slow-growing, bone-covered, noncancerous mass named as ossifying spindled and epithelioid tumor

It's not often that a pathologist gets to make a diagnosis that works for the patient by preventing treatment from occurring.

8 Dec 2025

Bone News and Research

SN101 iPSC-derived therapy relieves chronic pain and preserves joints

Metabolic imaging enables early response prediction in bone-dominant metastatic breast cancer

Exclusive licensing agreement accelerates PHD inhibitor development for anemia in CKD patients

Researchers identify chromatin accessibility changes driving stem cell transformation in MDS

Plant-based diets support healthy growth when properly planned for children

Study offers insight into how coffee and tea intake may influence bone health in older women

Researchers discover the enzyme responsible for chromothripsis in cancer

Expanded donor matching makes stem cell transplants accessible

Antibody therapy clears residual multiple myeloma in early trial

Why the form of vitamin B12 you take may matter more than your intake

Two ongoing studies show promise of pivekimab sunirine in treating aggressive blood cancers

Pirtobrutinib shows superior outcomes compared to common first-line combination treatment for CLL/SLL

People exposed to Agent Orange face higher risk of developing myelodysplastic syndrome

Routine blood test may flag hidden osteoporosis risk, study finds

Genome-edited immune cell therapy shows promise for treating aggressive blood cancer

Most T-cell/histocyte-rich large B-cell lymphoma patients can safely receive a less toxic treatment

Why female athletes need injury prevention rules built for women, not men

Poor dietary iron weakens lung memory T cells after flu infection

Novel wireless device uses light to send information directly to the brain

A slow-growing, bone-covered, noncancerous mass named as ossifying spindled and epithelioid tumor

Industry Focus eBook - Cell biology (5th edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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