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Sapio Sciences appoints Gordon McCall as Chief Operating Officer to drive global operational excellence

Sapio Sciences, the science-aware™ lab informatics platform, today announced the promotion of Gordon McCall to Chief Operating Officer (COO).

From Sapio Sciences 28 May 2025

Building Bridges to Scalable Allogeneic Cell Therapy

Rui Tostoes, Chief Technology Officer at ImmuneBridge, shares how his team is redefining preclinical development and large-scale manufacturing for allogeneic cell therapies.

From Hanson Wade Group - 7th Allogeneic Cell Therapies Summit 27 May 2025

Blood test pinpoints early Alzheimer’s risk with high accuracy

Researchers evaluated a fully automated plasma biomarker panel to detect early amyloid-β accumulation in cognitively unimpaired adults at risk for Alzheimer’s disease. Plasma p-tau217/Aβ42 emerged as the most robust and accurate blood-based marker for identifying preclinical amyloid pathology.

26 May 2025

Study sheds light on the link between gut microbiota, isoflavones, and geniposide hepatotoxicity

A recent study published in Engineering has shed light on the relationship between gut microbiota, isoflavones, and geniposide hepatotoxicity.

26 May 2025

Targeting astrocytes could boost immunotherapy effectiveness in glioblastoma

Our study investigated the role of astrocytes, an abundant cell type in the brain, in regulating an immune response against glioblastoma (GBM)-a highly aggressive brain cancer.

23 May 2025

New vascularized model of stem cell islets promises to improve diabetes research

Researchers led by Maike Sander, Scientific Director of the Max Delbrück Center, have developed a vascularized organoid model of hormone secreting cells in the pancreas.

23 May 2025

Powerful new toolkit targets vision loss in advanced retinal degeneration

Inherited retinal degenerations (IRDs) are a group of genetic disorders that lead to progressive vision loss as the light-sensing cells of the eye-the photoreceptors-die due to mutations in genes needed for their function and survival.

23 May 2025

SwRI designs bed netting systems for mosquito-based malaria control

Southwest Research Institute tapped into its drug formulation and manufacturing expertise to fabricate two bed netting prototypes targeting malaria-causing blood parasites.

21 May 2025

New technique rapidly tracks cell state changes through density measurements

Measuring the density of a cell can reveal a great deal about the cell's state. As cells proliferate, differentiate, or undergo cell death, they may gain or lose water and other molecules, which is revealed by changes in density.

21 May 2025

Personalized gene editing corrects fatal infant metabolic disorder in world-first treatment

Researchers have used a personalised base-editing gene therapy to successfully treat an infant with carbamoyl-phosphate synthetase 1 (CPS1) deficiency, a rare and life-threatening inborn error of metabolism. This pioneering approach chemically corrects the underlying mutation without cutting DNA, showing promise for precision treatment of ultrarare genetic disorders.

20 May 2025

Breakthrough microimager offers new possibilities for internal imaging

Researchers have developed an extremely thin, flexible imager that could be useful for noninvasively acquiring images from inside the body. The new technology could one day enable early and precise disease detection, providing critical insights to guide timely and effective treatment.

19 May 2025

What makes H5N1 a pandemic risk and how can we stop it?

A new PEARLS article in PLoS Pathogens reviews the rapid evolution and pandemic potential of emerging influenza A viruses, with a focus on H5N1. It highlights scientific advances and future strategies to outpace the virus, from next-generation vaccines to AI-driven antiviral discovery.

19 May 2025

Targeting cGAS shows promise for treating cardiac dysfunction after cardiac arrest

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Cardiac dysfunction is a prevalent and serious complication after cardiac arrest (CA), yet limited therapeutic interventions are available.

19 May 2025

Electromagnetic waves disrupt SARS-CoV-2 spike protein and lower infectivity

Researchers demonstrated that specific electromagnetic wave frequencies can disrupt the SARS-CoV-2 Spike protein structure in virus-like particles, leading to reduced infectivity in cell models. This proof-of-concept study suggests new avenues for non-chemical viral inactivation methods.

18 May 2025

Customized CRISPR gene editing therapy successfully treats infant with rare disease

In a historic medical breakthrough, a child diagnosed with a rare genetic disorder has been successfully treated with a customized CRISPR gene editing therapy by a team at Children's Hospital of Philadelphia (CHOP) and Penn Medicine.

15 May 2025

TMEM219 inhibition shows promise in restoring intestinal health in IBD

An international study led by Paolo Fiorina from Boston Children's Hospital and in collaboration with researchers from University of Milan highlights the beneficial effect of inhibiting the death receptor TMEM219 to restore mucosal healing in inflammatory bowel diseases.

15 May 2025

Once-daily oral treatment shows positive results in first human study for obesity treatment

A first-in-human study of an investigational once-daily oral treatment for obesity (SYNT-101) demonstrated positive preliminary data for the safe and effective redirection of nutrient absorption into the lower intestine, the weight loss and metabolic management mechanism behind gastric bypass surgery.

14 May 2025

New light-based 3D printing technique advances tissue engineering

Researchers at the Terasaki Institute for Biomedical Innovation (TIBI) have developed a technique that could help advance treatments in tissue engineering.

13 May 2025

New study identifies wedelolactone as a potent topical treatment for psoriasis

Announcing a new publication for Acta Materia Medica journal. Psoriasis is a chronic inflammatory disorder for which phosphodiesterase-4 (PDE4) inhibitors have emerged as promising therapeutic agents due to an ability to regulate inflammatory signaling pathways.

13 May 2025