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Amsterdam UMC researchers overturn long-standing biological pacemaker dogma

Researchers from Amsterdam UMC have overturned a key assumption in the biological pacemaker field.

11 Jun 2026

Intravenous statins during heart attack reduce cardiac muscle damage

Reducing the damage sustained by the heart during a myocardial infarction remains one of the major challenges in cardiology, even when the blocked coronary artery is reopened in a timely manner.

11 Jun 2026

Circadian clock protein BMAL1 enhances inflammatory responses in immune cells

Daily life is shaped by the solar day, influencing when we wake up, eat, work, and sleep. Inside the body, a similar internal timing system -present in nearly every cell- known as the circadian clock, synchronizes many biological functions such as sleep, metabolism, hormone release, and even the immune system's activity.

11 Jun 2026

Gut bacterial molecule reduces intestinal inflammation by slowing cell energy

Enterobactin, a molecule produced by gut bacteria, may hold a surprising key to reducing intestinal inflammation. Not by attacking the immune system directly, but by temporarily slowing down the cell's own energy production.

11 Jun 2026

Running a marathon triggers measurable heart changes

Acute cardiac responses to marathon running include biomarker spikes and structural changes, though their long-term impact on heart health needs further study.

11 Jun 2026

New treatment platform delivers full-length mRNA for Duchenne muscular dystrophy

A new treatment platform developed by researchers at The University of Texas MD Anderson Cancer Center was able to deliver messenger RNA (mRNA) of the full-length DMD gene into preclinical models of Duchenne muscular dystrophy, successfully restoring the production of an important muscle protein, dystrophin, and dramatically improving muscle strength, endurance and function in vivo.

11 Jun 2026

Chronic pancreatitis care must expand beyond simple pain management

Chronic pancreatitis (CP) diminishes quality-of-life (QoL) across mobility, self-care, daily activities, mental health, and pain-not just abdominal discomfort-according to a new Mayo Clinic study available online on August 27, 2025, and published in Volume 9, Issue 1 of the Journal of Pancreatology on March 30, 2026.

11 Jun 2026

A hidden immune pathway may help explain why Alzheimer’s inflammation persists

Researchers found that KAT7 promotes CMPK2-driven mitochondrial DNA release in microglia, activating inflammatory cGAS-STING and NLRP3 pathways linked to Alzheimer’s disease.

11 Jun 2026

Scientists reveal how cGAS-STING fuels brain inflammation and neurodegeneration

The cGAS-STING pathway is emerging as a key driver of chronic neuroinflammation through its effects on glial activation, neuronal stress, blood-brain barrier integrity, and type I interferon signaling. The review highlights why selective, context-dependent modulation of cGAS-STING could help treat neurodegenerative diseases, while preserving its essential roles in antiviral defense and tumor surveillance.

10 Jun 2026

Western diet weakens the gut’s nervous system through iron-dependent damage

A JCI study found that exposure to a Western diet in mice and to palmitic acid in murine and ex vivo human enteric nervous system models triggered ferroptosis, characterized by iron loading, lipid peroxidation, mitochondrial stress, and enteric neuronal loss. Boosting Nrf2 signaling protected enteric neurons and prevented Western diet-induced delayed colonic transit in mice, pointing to a potential pathway linking dietary fat exposure to gut motility dysfunction.

10 Jun 2026

Researchers uncover immune loop driving Sjögren's disease progression

Sjögren's disease is a widespread chronic autoimmune disorder that attacks the body's own glands, yet its underlying disease mechanisms remain poorly understood.

10 Jun 2026

Study identifies an important driver of inflammatory bowel disease

Researchers at the Nuffield Department of Medicine, University of Oxford, together with Newcastle University's Translational and Clinical Research Institute and the Department of Immunology at Cambridge University Hospitals NHS Foundation Trust, have identified an important driver of inflammatory bowel disease (IBD).

10 Jun 2026

Short-term fasting may reduce inflammation linked to gum disease

People who follow a short-term low-calorie diet may have reduced markers of inflammation associated with gum disease.

10 Jun 2026

Brain injury survivors face higher risk of brain cancer death

Daniel Daneshvar, MD, PhD, director of the HealthSpan Lab and Chief of the Department of Physical Medicine and Rehabilitation at Mass General Brigham, and Charlotte Luster, of the HealthSpan Lab, are the senior and lead authors of a paper published in Neuroepidemiology, "Brain Cancer Mortality following Traumatic Brain Injury (TBI): A TBI Model Systems Study."

10 Jun 2026

Review explores impact of extreme endurance running on heart health

Changes to the heart linked to marathon running vary by age, sex, and training level, finds a synthesis of the available data, published in the open access journal BMJ Open Sport & Exercise Medicine.

10 Jun 2026

Oral swab detects hidden inflammation in rare lung disease

Researchers at UTHealth Houston have identified different types of hidden systemic inflammation in patients with primary ciliary dyskinesia, even when they are not experiencing acute illness.

9 Jun 2026

Mycoplasma genitalium unlikely to drive recurrent preterm deliveries

A new study from UTHealth Houston found that the common sexually transmitted infection, Mycoplasma genitalium, also known as MGen, does not appear to increase the risk of recurrent preterm birth.

9 Jun 2026

Excess weight identified as key driver for cardiovascular-kidney-metabolic syndrome

The first-ever clinical guideline for cardiovascular-kidney-metabolic syndrome, or CKM syndrome, identifies excess weight, especially in the abdomen, as a key driver for the syndrome. T

9 Jun 2026

Advanced MRI scans predict chronic kidney disease in patients undergoing nephrectomy

An investigator at the Icahn School of Medicine at Mount Sinai has received international recognition for innovative imaging research that may help physicians identify patients at increased risk of chronic kidney disease (CKD) before they undergo surgery for kidney tumors.

9 Jun 2026

Type 2 diabetes elevates periodontitis risks regardless of glycemic control

Persons with diabetes have an increased risk of periodontitis (gum disease) and tooth loss. The risk of inflammation and bone loss at dental implants was also higher. These are the findings of a thesis at the University of Gothenburg.

9 Jun 2026