Therapeutics News and Research

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Medically active component of cannabis does not impact driving ability, study shows

A landmark study on how cannabis affects driving ability has shown that cannabidiol (CBD), a cannabis component now widely used for medical purposes, does not impair driving, while moderate amounts of the main intoxicating component tetrahydrocannabinol (THC) produce mild driving impairment lasting up to four hours.

1 Dec 2020

Cancer-killing virus developed at City of Hope activates the immune system against colon cancer

City of Hope scientists have developed a cancer-killing virus by combining the oncolytic virus CF33 with an immune checkpoint inhibitor.

1 Dec 2020

Gut microbiota directly shapes the makeup of human immune system, shows study

MSK researchers have uncovered an important finding about the relationship between the microbiota and the immune system, showing for the first time that the concentration of different types of immune cells in the blood changes in relation to the presence of different bacterial strains in the gut.

1 Dec 2020

New combination technique separates cell types, may prove effective against pathogens

To develop effective therapeutics against pathogens, scientists need to first uncover how they attack host cells. An efficient way to conduct these investigations on an extensive scale is through high-speed screening tests called assays.

1 Dec 2020

Nucleic acid-hydrolyzing scFv 3D8 exhibits potent antiviral effects on SARS-CoV-2

3D8, a 27-kDa recombinant antibody fragment, was found in autoimmune-prone Murphy Roths Large mice. The single-chain variable fragment (scFv) has the nucleic acid hydrolyzing activity and is shown to degrade DNA or mRNA of viruses in infected cells.

30 Nov 2020

Researchers find way for customized programming of human stem cells

Induced pluripotent stem cells (iPS) have the potential to convert into a wide variety of cell types and tissues for drug testing and cell replacement therapies. However, the "recipes" for this conversion are often complicated and difficult to implement.

30 Nov 2020

Wyss Institute’s eRapid technology licensed to The iQ Group Global

Today, the Wyss Institute for Biologically Inspired Engineering at Harvard University announced that its eRapid technology has been licensed to The iQ Group Global for COVID-19 diagnostic applications.

30 Nov 2020

Rutgers leading a clinical trial assessing combination treatment for coronavirus

Rutgers is leading a clinical trial assessing the combination of nitazoxanide, ribavirin and hydroxychloroquine to treat people 21 or older who are infected with SARS-CoV-2 and are asymptomatic or mildly symptomatic.

30 Nov 2020

UC San Diego chosen to lead an international $28-million grant for HIV/AIDS clinical trials

University of California San Diego Collaborative Clinical Trials Unit has been selected by the National Institutes of Health to lead and administer an international seven-year, $28-million grant for science-driven clinical trials that deliver innovative, efficient results needed to turn the corner on the HIV/AIDS pandemic.

30 Nov 2020

How pharma money colors Operation Warp Speed’s quest to defeat COVID

April 16 was a big day for Moderna, a Massachusetts biotech company on the verge of becoming a front-runner in the U.S. government's race for a coronavirus vaccine. It had received roughly half a billion dollars in federal funding to develop a COVID shot that might be used on millions of Americans.

30 Nov 2020

New AI solution that can determine the shape of proteins could 'revolutionize' medical research

DeepMind’s AI solution, AlphaFold, has succeeded in determining the shape of proteins with a level of accuracy similar to that of laboratory experiments.

30 Nov 2020

Resveratrol shows potential as SARS-CoV-2 antiviral, study finds

A recent study reveals that resveratrol, a phenolic compound produced by spermatophytes, can inhibit the viral replication SARS-CoV-2.

27 Nov 2020

N439K mutation of SARS-CoV-2 may be more infectious and antibody resistant than Wuhan strain

Researchers from the Harbin Institute of Technology, China, modeled the complexes formed between the RBD and the human ACE2 and monoclonal antibodies.

27 Nov 2020

Combining cell engineering with machine learning to design living medicines for cancer

Finding medicines that can kill cancer cells while leaving normal tissue unscathed is a Holy Grail of oncology research.

26 Nov 2020

Researchers discover blood gene signatures that can predict COVID-19 severity

A team of scientists from the University of Chicago, NCH Healthcare System and the University of South Florida has identified a specific set of genes associated with a poor prognosis of COVID-19.

26 Nov 2020

Scientists use 3D mapping techniques to unravel mystery of blood stem cells

Princess Margaret scientists have revealed how stem cells are able to generate new blood cells throughout our life by looking at vast, uncharted regions of our genetic material that hold important clues to subtle biological changes in these cells.

25 Nov 2020

Inhibiting SARS-CoV-2 cell entry with monoclonal antibodies against staphylococcal enterotoxin B superantigen

In a recent cutting-edge study, US researchers unveiled an anti-staphylococcal enterotoxin B monoclonal antibody that can be repurposed to target the cleavage site of the SARS-CoV-2 spike glycoprotein and, in turn, inhibit viral infection. Their findings are currently available on bioRxiv preprint server.

25 Nov 2020

Therapeutics News and Research

Medically active component of cannabis does not impact driving ability, study shows

Cancer-killing virus developed at City of Hope activates the immune system against colon cancer

Gut microbiota directly shapes the makeup of human immune system, shows study

New combination technique separates cell types, may prove effective against pathogens

Nucleic acid-hydrolyzing scFv 3D8 exhibits potent antiviral effects on SARS-CoV-2

Researchers find way for customized programming of human stem cells

Wyss Institute’s eRapid technology licensed to The iQ Group Global

Rutgers leading a clinical trial assessing combination treatment for coronavirus

UC San Diego chosen to lead an international $28-million grant for HIV/AIDS clinical trials

How pharma money colors Operation Warp Speed’s quest to defeat COVID

New AI solution that can determine the shape of proteins could 'revolutionize' medical research

Resveratrol shows potential as SARS-CoV-2 antiviral, study finds

N439K mutation of SARS-CoV-2 may be more infectious and antibody resistant than Wuhan strain

Combining cell engineering with machine learning to design living medicines for cancer

Researchers discover blood gene signatures that can predict COVID-19 severity

Scientists use 3D mapping techniques to unravel mystery of blood stem cells

Inhibiting SARS-CoV-2 cell entry with monoclonal antibodies against staphylococcal enterotoxin B superantigen

Convalescent plasma therapy ineffective in treating severe COVID-19, study finds

Cell survival protein could protect kidneys from damage caused by cancer therapies

The American Lung Association say to wear masks to stop the spread of COVID-19; Here’s why

Next-generation therapeutics eBook eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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