Immune System News and Research

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Immune-regulating molecule may offer new treatment approach for IBD patients

Mayo Clinic researchers have identified an immune-regulating molecule that may help explain why some patients with inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis, do not respond to commonly used therapies.

13 May 2026

Penn researchers develop ApexGO to enhance promising antibiotic candidates

Researchers at the University of Pennsylvania have developed ApexGO, a novel, AI-powered method for turning promising but imperfect antibiotic candidates into more potent ones.

13 May 2026

Disrupted circadian rhythms may accelerate dementia-related brain inflammation

Alzheimer's disease and other dementias impact approximately 55 million people worldwide, including 7.2 million cases in the United States alone.

13 May 2026

New malaria vaccine offers long-lasting protection without refrigeration

Malaria is a deadly disease killing more than half a million people every year, but a new vaccine is showing promise as it not only offers long-lasting strong protection but also inhibits transmission of malaria by mosquitos.

13 May 2026

Common tuberculosis screening test could predict long-term patient survival

Scientists have long known that the immune system plays a key role in aging. As people age, they have weaker responses to vaccination, greater risks of infection and higher levels of inflammation.

11 May 2026

Gene mapping highlights strong immune and brain connections in depression

Neurons and white blood cells differ greatly in shape, function, and location within the body. However, researchers at the University of São Paulo (USP) in Brazil discovered that certain genes are equally dysregulated in both cell types in people with depression.

11 May 2026

Scientists discover immune cell control switch to destroy fungal infections

Scientists at the University of East Anglia (UK) have contributed to discovering a "control switch" inside our immune cells that helps the body destroy dangerous fungal infections.

11 May 2026

Rockefeller scientists reveal how HIV strains escape broadly neutralizing antibodies

Broadly neutralizing antibodies (bNAbs) are among the most promising new treatments for HIV, offering the potential to forego traditional daily dose of antiretroviral drugs.

11 May 2026

Andes hantavirus outbreak highlights global spillover and transmission risks

A Virginia Tech disease ecologist said the outbreak of Andes hantavirus aboard the international MV Hondius cruise ship underscores how little scientists still know about the viruses circulating silently in wild rodent populations before they spill into humans.

11 May 2026

Slow and steady wins: Low-dose peanut immunotherapy safely desensitizes 82% of preschoolers in landmark trial

A Swedish randomized trial found that slow up-dosing peanut oral immunotherapy with a low maintenance dose helped 82% of preschool children achieve sustained peanut tolerance after three years. The approach proved safer than conventional protocols, with severe reactions uncommon and strong family adherence throughout treatment.

10 May 2026

Multi-center research initiative aims to improve glioblastoma patient outcomes

Investigators at the UCLA Health Jonsson Comprehensive Cancer Center are part of a new multi-institution research effort aimed at improving care and outcomes for patients diagnosed with glioblastoma, one of the most aggressive and difficult-to-treat cancers.

8 May 2026

Study challenges assumptions about testosterone’s role in brain cancer

Scientists have long suspected that androgens, male sex hormones like testosterone, may help tumors grow because the hormones can suppress immune responses to some cancers.

8 May 2026

Engineered regulatory T cells offer a path toward immunosuppression-free transplants

Organ transplantation remains the cornerstone treatment for end-stage organ failure. While conventional broad-spectrum immunosuppression effectively controls acute rejection, it fails to address chronic rejection and carries long-term side effects including infection, malignancy, and metabolic disorders.

8 May 2026

Study reveals why women face higher autoimmune disease risks

Ahead of World Lupus Day on May 10, new research from the Garvan Institute of Medical Research and UNSW Sydney helps explain why women are significantly more likely to be diagnosed with an autoimmune disease – a condition where the immune system misfires and mistakenly attacks the body's own healthy tissues.

7 May 2026

Cell swelling in macrophages may trigger stronger inflammatory immune responses

As part of the body's first line of defense against foreign invaders, macrophages play an integral role in the innate immune system.

7 May 2026

Nighttime heat waves linked to asthma emergency room visits in Baltimore

Hospitals in Baltimore see an uptick in asthma-related emergency room cases in the weeks following nighttime heat waves in their neighboring communities, according to new research from Johns Hopkins University.

7 May 2026

A new combined therapy to boost the immune system against cancer

Cancer immunotherapy is built on a simple but powerful idea: the immune system can recognize and destroy cancer cells if it is properly activated. In many patients, however, this response is too weak or too slow to be effective.

7 May 2026

Reverse ecology approach reveals hidden complexity in gut microbiome

The human gut harbors a complex ecosystem of trillions of microorganisms (the microbiome), which influences digestion, the immune system and metabolism.

7 May 2026

Researchers identify new treatment vulnerabilities in pancreatic cancer progression

The review offers important insights for patients and families by explaining why pancreatic cancer has proven so resistant to treatment, and where new hope may emerge.

6 May 2026

New immunotherapy strategy overcomes resistance in colorectal cancer treatment

Researchers at the Icahn School of Medicine at Mount Sinai and the Mount Sinai Tisch Cancer Center have identified a promising new strategy to overcome resistance to immunotherapy in colorectal cancer, one of the leading causes of cancer-related deaths worldwide.

6 May 2026