Alzheimer's Disease News and Research

RSS

Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

Women with Down syndrome show more advanced Alzheimer's signs at diagnosis

According to research by the University of California, Irvine, women with Down syndrome have more advanced signs of Alzheimer's disease than men do at the average age of diagnosis, which is the same for both sexes.

12 Aug 2025

Cats with dementia show brain changes similar to Alzheimer’s in humans

Cats with dementia have brain changes similar to those of people with Alzheimer's disease, offering a valuable model for studying the condition in humans, a study says.

12 Aug 2025

Study establishes a causal link between mitochondrial dysfunction and neurodegenerative diseases

Mitochondria, the tiny organelles without which our bodies would be deprived of energy, are gradually revealing their mysteries.

11 Aug 2025

New insights into how keto diet can restore cognitive function following status epilepticus

Epilepsy affects over 70 million people worldwide, and a significant portion of patients suffer from drug-resistant epilepsy (DRE), where standard medications fail.

11 Aug 2025

Alzheimer’s research reaches a critical tipping point

One-third of people older than 85 in the United States are estimated to live with Alzheimer's disease today, according to the National Institute on Aging.

8 Aug 2025

Uncovering the secrets of ‘SuperAgers’ and cognitive longevity

For 25 years, scientists at Northwestern Medicine have been studying individuals aged 80 and older - dubbed "SuperAgers" - to better understand what makes them tick.

8 Aug 2025

Scientists link brain lithium loss to early Alzheimer’s changes

Researchers have discovered that naturally occurring lithium in the brain is depleted early in Alzheimer’s disease, especially in the prefrontal cortex, and that restoring physiological levels with lithium orotate in mice can prevent brain damage and memory loss. The findings suggest lithium deficiency may be a modifiable risk factor for Alzheimer’s.

7 Aug 2025

New antibody delivery system boosts Alzheimer's treatment in mice

A newly engineered antibody transport vehicle targeting the transferrin receptor enables enhanced delivery of anti-amyloid antibodies to the brains of mouse models of Alzheimer's disease, researchers report.

7 Aug 2025

New microscope system reveals molecular activity deep in the brain tissue

Both for research and medical purposes, researchers have spent decades pushing the limits of microscopy to produce ever deeper and sharper images of brain activity, not only in the cortex but also in regions underneath such as the hippocampus.

7 Aug 2025

Cedars-Sinai study finds new way to combat Alzheimer’s in preclinical models

In a preclinical study, Cedars-Sinai investigators found that boosting angiotensin converting enzyme (ACE) in key immune cells called microglia in the brain helped protect the brains of specially bred laboratory mice against Alzheimer's disease.

6 Aug 2025

UC Irvine researchers discover naturally occurring compounds to rejuvenate aging brain cells

Researchers at the University of California, Irvine have identified a promising nonpharmaceutical treatment that rejuvenates aging brain cells and clears away the buildup of harmful proteins associated with Alzheimer's disease.

5 Aug 2025

Stress internalization increases risk of age-related cognitive decline in Chinese seniors

Stress internalization is a significant risk factor for age-related cognitive decline in older Chinese Americans, according to Rutgers Health researchers.

5 Aug 2025

Nighttime caffeine linked to increased impulsivity

Do you find yourself reaching for a cup of coffee at night to stay alert? A new study from The University of Texas at El Paso suggests you might want to reconsider.

5 Aug 2025

Researchers discover amyloid protein buildup in bone marrow of aging mice

A recent study led by a team of researchers at The Johns Hopkins University School of Medicine examining aging mice has provided what is believed to be the first evidence that amyloid beta protein-small, sticky protein fragment found in people with Alzheimer's disease (AD)-particles build up in the bone marrow of the animals, although not in the exact same form as the large, dense plaques found in the brains of people with Alzheimer's disease.

5 Aug 2025

KAIST scientists achieve first total synthesis of herpotrichone with neuroprotective properties

"Herpotrichone" is a natural substance that has been evaluated highly for its excellent ability to suppress inflammation in the brain and protect nerve cells, displaying significant potential to be developed as a therapeutic agent for neurodegenerative brain diseases such as Alzheimer's disease and Parkinson's disease.

5 Aug 2025

New brainwave marker identified for Alzheimer’s detection

Using a custom-built tool to analyze electrical activity from neurons, researchers at Brown University have identified a brain-based biomarker that could be used to predict whether mild cognitive impairment will develop into Alzheimer's disease.

4 Aug 2025

New research unveils vast influence of B vitamins on health and disease

Eight essential nutrients make up the suite of B vitamins also known as the B complex. Researchers from Tufts University and elsewhere have revealed that these B vitamins influence a vast spectrum of human health and disease, including cognitive function, cardiovascular health, gastric bypass recovery, neural tube defects, and even cancer.

4 Aug 2025

Johns Hopkins uncovers protein's unexpected role in brain signaling

Researchers at Johns Hopkins Medicine say they unexpectedly found new information about a protein's special role in getting brain cells to communicate at the right time and place in experiments with genetically engineered mice.

4 Aug 2025

Researchers trace metabolic superpowers of hibernators to shared DNA

Animals that hibernate are incredibly resilient. They can spend months without food or water, muscles refusing to atrophy, body temperature dropping to near freezing as their metabolism and brain activity slow to a crawl.

1 Aug 2025

Synthetic torpor moves closer to real-world medical use

Nature is often the best model for science. For nearly a century, scientists have been trying to recreate the ability of some mammals and birds to survive extreme environmental conditions for brief or extended periods by going into torpor, when their body temperature and metabolic rate drop, allowing them to preserve energy and heat.

1 Aug 2025