immunity News and Research

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Genome-edited immune cell therapy shows promise for treating aggressive blood cancer

A groundbreaking new treatment using genome-edited immune cells, developed by scientists at UCL (University College London) and Great Ormond Street Hospital (GOSH), has shown promising results in helping children and adults fight a rare and aggressive form of blood cancer called T-cell acute lymphoblastic leukemia (T-ALL).

8 Dec 2025

Poor dietary iron weakens lung memory T cells after flu infection

Dietary iron deficiency in mice alters lung T cell activation during influenza infection and leads to memory T cells that are present in normal or increased numbers but have impaired antiviral cytokine responses. These functional deficits are most pronounced in lung CD8-positive memory T cells and persist even under optimal recall conditions.

8 Dec 2025

Targeted approach of immunotherapy improves sepsis outcomes

Immunotherapy for sepsis is effective when doctors tailor the treatment precisely to the patient's immune system condition.

8 Dec 2025

Researchers discover a surprising ally in the fight against insulin resistance and type 2 diabetes

An international research team led by Professor Marc-Emmanuel Dumas at Imperial College London & CNRS together with Prof. Patrice Cani (Imperial & University of Louvain, UCLouvain), Dr. Dominique Gauguier (Imperial & INSERM, Paris) and Prof. Peter Liu (University of Ottawa Heart Institute) has uncovered a surprising ally in the fight against insulin resistance and type 2 diabetes: a microbial metabolite called trimethylamine (TMA).

8 Dec 2025

Novel antibody suppresses primary tumor growth and spread of triple-negative breast cancer

Triple-negative breast cancer (TNBC) is one of the most aggressive and treatment-resistant forms of breast cancer. It grows quickly, spreads early and lacks the hormone receptors that make other breast cancers treatable with targeted therapies.

5 Dec 2025

Pre-workout supplements linked to dangerously short sleep

Pre-workout supplements are associated with lower sleep duration in young Canadians, highlighting the need for guidance on timing and caffeine content.

5 Dec 2025

Organ-on-a-chip system reveals how aging weakens vaccine-driven anti-cancer immunity

Dr. Vadim Jucaud's lab at the Terasaki Institute has introduced a new organ-on-a-chip platform that recapitulates age-dependent immune responses, offering a more accurate testing bed for evaluating cancer vaccine performance in older adults, the population most affected by cancer and often overlooked in traditional preclinical testing.

4 Dec 2025

Single-dose dengue vaccine will benefit populations in hard-to-reach regions

A world-first single-dose vaccine against the dengue virus, manufactured and approved for use in Brazil, will especially benefit populations in hard-to-reach regions of the country such as the Amazon, say disease specialists.

4 Dec 2025

Injectable scaffold vaccine shows strong protection against implant-related MRSA

Research reveals that silica scaffolds can train the immune system against S. aureus, offering a novel approach to prevent orthopedic device infections.

4 Dec 2025

NeuMap unveils the hidden architecture and life-long patterns of human neutrophils

Neutrophils are the most abundant immune cells in the body and the first to respond to infection or tissue damage.

3 Dec 2025

How tick saliva reprograms the skin’s immune defenses

A research team led by the Medical University of Vienna has gained new insights into how ticks influence the human immune system in order to introduce pathogens.

2 Dec 2025

RFK Jr. wants to delay the hepatitis B vaccine. Here’s what parents need to know.

Working out of a tribal-owned hospital in Anchorage, Alaska, liver specialist Brian McMahon has spent decades treating the long shadow of hepatitis B. Before a vaccine became available in the 1980s, he saw the virus claim young lives in western Alaskan communities with stunning speed.

2 Dec 2025

Generative AI aids discovery of ISM3830's novel scaffold

Casitas B-lineage lymphoma-b (CBLB) is an E3 ubiquitin–protein ligase that functions as an intracellular checkpoint and master negative regulator of T‑cell and natural killer (NK) cell activation, playing a central role in modulating T-cell activation and immune tolerance, and its inhibition enhances T cells and NK cells function, also provides a strategy for the function restoration of exhausted T cells.

1 Dec 2025

Innate immunity and metabolic stress drive a unique form of cell death

In several disease conditions, including infections and cancers, innate immune activation and nutrient scarcity occur together.

1 Dec 2025

Why green tea delivers the strongest health benefits

This review examines tea's health effects, highlighting green tea's benefits for heart health and cognition, and warns about risks in processed tea products.

1 Dec 2025

Measles deaths plummet but infections surge worldwide

Global immunization efforts have led to an 88% drop in measles deaths between 2000 and 2024, according to a new report from the World Health Organization (WHO). Nearly 59 million lives have been saved by the measles vaccine since 2000.

29 Nov 2025

Early-infancy infection with RSV increases the risk of developing childhood asthma

Belgian scientists from VIB and Ghent University (UGent), together with Danish collaborators, have uncovered compelling evidence that early-infancy infection with respiratory syncytial virus (RSV) significantly increases the risk of developing childhood asthma-especially in children with a family history of allergy or asthma.

29 Nov 2025

immunity News and Research

Genome-edited immune cell therapy shows promise for treating aggressive blood cancer

Poor dietary iron weakens lung memory T cells after flu infection

Targeted approach of immunotherapy improves sepsis outcomes

Researchers discover a surprising ally in the fight against insulin resistance and type 2 diabetes

Novel antibody suppresses primary tumor growth and spread of triple-negative breast cancer

Pre-workout supplements linked to dangerously short sleep

Organ-on-a-chip system reveals how aging weakens vaccine-driven anti-cancer immunity

Single-dose dengue vaccine will benefit populations in hard-to-reach regions

Injectable scaffold vaccine shows strong protection against implant-related MRSA

NeuMap unveils the hidden architecture and life-long patterns of human neutrophils

How tick saliva reprograms the skin’s immune defenses

RFK Jr. wants to delay the hepatitis B vaccine. Here’s what parents need to know.

Generative AI aids discovery of ISM3830's novel scaffold

Innate immunity and metabolic stress drive a unique form of cell death

Why green tea delivers the strongest health benefits

Measles deaths plummet but infections surge worldwide

Early-infancy infection with RSV increases the risk of developing childhood asthma

How the gut microbiome links obesity to colorectal cancer

Tattoo ink alters immune cells and weakens some vaccine responses

New study links inherited mitochondrial DNA mutation to disrupted immune balance

Exploring Strategies for Targeting Kinases in Innate Immunity eBook

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

How microplastics and bacteria interact to drive antibiotic resistance

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