Drug Discovery News and Research

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The drug discovery process begins with recognizing a disease or clinical condition in which there is a lack of adequate medical treatment. Once a potential drug has been identified, pre-clinical research can begin. This process includes several stages; the first of which involves identifying and validating the prospective drug’s target through assay development, high throughput screening, hit identification and finally, lead optimization. Once the pre-clinical process is complete, the newly synthesized drug candidate is selected for future clinical development.

New human tissue chips aim to replace animal testing

Animal testing has long been the standard for evaluating new drugs before they reach human patients. But when it comes to cancer immunotherapy drugs, animal models often fail to predict which immunotherapies might produce harmful side effects in humans because they do not have the same responses or the same cell receptors.

11 Aug 2026

Lab-grown mini tumors help scientists predict breast cancer treatment success

Researchers at UC San Francisco have developed a new method to predict how different types of breast cancer will respond to treatment, using patient data from the I-SPY2 breast cancer trial and rapid testing on lab-grown mini tumors.

11 Aug 2026

Spatial transcriptomics study elucidates cellular dynamics during heart transplant rejection

A new study that explores gene expression during heart transplant rejection marks a step forward for precision medicine approaches to treat organ rejection.

10 Aug 2026

PRDM16 regulates the balance between proliferation and maturation in human cardiomyocytes

Understanding how heart muscle cells stop dividing and acquire the characteristics needed to sustain lifelong cardiac function remains one of the greatest challenges in cardiovascular biology.

7 Aug 2026

Thinning cancer cells' sugar coating could expose tumors to immune attack

Like spies evading detection through being masters of disguise, many cancer cells are adorned with a copious coat of sugar-derived molecules that throws the proverbial hounds of our immune systems off the scent.

7 Aug 2026

Study identifies a novel direct drug target for head and neck squamous cell carcinoma

Chemotherapy remains a cornerstone of treatment for head and neck cancers, the seventh-most common cancer type worldwide.

6 Aug 2026

International team builds comprehensive cancer models for future drug development

To develop new targeted treatments for cancer, scientists need tissue models that accurately represent the genetic and molecular traits of the cancer they're studying.

5 Aug 2026

Artificial cells offer new insights into living cell behavior

Using simple artificial cells, a research group led by Makito Miyazaki of the RIKEN Center for Integrative Medical Sciences (IMS) in Japan have uncovered fundamental physical principles that govern how living cells change their shape.

5 Aug 2026

Insilico Medicine highlights AI-powered biological target discovery for rare sinonasal cancer

Insilico Medicine ("Insilico"), a clinical-stage generative artificial intelligence (AI)-driven biotechnology company, today announced the publication of a collaborative study in the journal npj Precision Oncology.

4 Aug 2026

Immune cell navigation breakthrough offers hope for better anti-inflammatory drugs

A scientific collaboration between the University of Bath (UK) and the UMass Chan Medical School (USA) have determined how a specific type of white blood cells, called neutrophils, move through the body.

31 Jul 2026

Soy lysolecithin reduces salt-induced hypertension and cognitive decline

High salt (HS) intake is a major global health concern, closely linked to hypertension and growing evidence of cognitive and emotional decline.

31 Jul 2026

Insilico unveils standardized evaluation framework to validate AI-driven drug discovery models

As general-purpose and domain-specific AI models rapidly infiltrate drug discovery, one critical question looms over the pharmaceutical sector: Can these models actually discover drugs, or are they just good at taking tests?

30 Jul 2026

Texas A&M researchers build AI tools for tuberculosis drug discovery

When researchers screen potential tuberculosis drugs, they often end up with too many options. Some look promising but later prove to be costly dead ends.

30 Jul 2026

New chemical method breaks rules to speed up drug discovery

Binghamton University chemists have discovered a new mechanism that could potentially lead to quicker outcomes in pharmaceutical research.

30 Jul 2026

FDA grants fast track designation to Insilico's AI-designed mesothelioma drug candidate

Insilico Medicine ("Insilico"; HKEX: 3696), a clinical-stage generative artificial intelligence (AI)-driven drug discovery company, today announced that ISM6331, a novel, potential best-in-class pan-TEAD inhibitor driven by Insilico's proprietary AI, has received Fast Track Designation (FTD) from the U.S.

29 Jul 2026

Primate study reveals molecular basis of red-green color vision

Human color vision depends on three types of cone cells in the retina. Although all three contain the same light-absorbing molecule, 11-cis-retinal, differences in the surrounding protein determine sensitivity to red, green, or blue light.

27 Jul 2026

Advancing Drug Safety Assessment With AI, Predictive Modeling, and Human-Relevant Data

James McDonagh discusses how AI and machine learning are transforming drug discovery and safety assessment, enhancing toxicology and decision-making processes.

27 Jul 2026

Leerink Partners report names Carterra a core enabler of the $7 B "Lab-in-the-Loop" antibody discovery market

Carterra®, a leading provider of high-throughput surface plasmon resonance (HT-SPR) platforms for antibody and small molecule discovery, today highlighted new research from Leerink Partners identifying Carterra as a key enabling technology in the fast-growing market for AI-driven biologics drug discovery.

From Carterra Inc. 27 Jul 2026

Novogene Europe expands single-cell sequencing capability at Cambridge Omics Centre

Novogene Europe, a multiomics research services partner, today announced that it has expanded its single-cell RNA sequencing capability at its Cambridge Omics Centre.

From Novogene Europe 27 Jul 2026

Researchers develop artery-on-a-chip platform to predict stroke risk

Predicting an individual's risk of ischemic stroke is difficult because thrombosis embolization-the process of a blood clot detaching from the area where it formed and traveling to and then sticking in another blood vessel-is based on factors that are unique to each person.

23 Jul 2026

Drug Discovery News and Research

Further Reading

New human tissue chips aim to replace animal testing

Lab-grown mini tumors help scientists predict breast cancer treatment success

Spatial transcriptomics study elucidates cellular dynamics during heart transplant rejection

PRDM16 regulates the balance between proliferation and maturation in human cardiomyocytes

Thinning cancer cells' sugar coating could expose tumors to immune attack

Study identifies a novel direct drug target for head and neck squamous cell carcinoma

International team builds comprehensive cancer models for future drug development

Artificial cells offer new insights into living cell behavior

Insilico Medicine highlights AI-powered biological target discovery for rare sinonasal cancer

Immune cell navigation breakthrough offers hope for better anti-inflammatory drugs

Soy lysolecithin reduces salt-induced hypertension and cognitive decline

Insilico unveils standardized evaluation framework to validate AI-driven drug discovery models

Texas A&M researchers build AI tools for tuberculosis drug discovery

New chemical method breaks rules to speed up drug discovery

FDA grants fast track designation to Insilico's AI-designed mesothelioma drug candidate

Primate study reveals molecular basis of red-green color vision

Advancing Drug Safety Assessment With AI, Predictive Modeling, and Human-Relevant Data

Leerink Partners report names Carterra a core enabler of the $7 B "Lab-in-the-Loop" antibody discovery market

Novogene Europe expands single-cell sequencing capability at Cambridge Omics Centre

Researchers develop artery-on-a-chip platform to predict stroke risk

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