Dysbiosis News and Research

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Dysbiosis is a condition caused by an imbalance in the bacterial community (microbiome) of the human gut. Dysbiosis disrupts the ecoystsem of the gut, resulting in symptoms such as diarrhea, constipation, bloating, and indigestion, among others.

Yoga and meditation show promise for gut health

This systematic review found that yoga and Buddhist meditation were associated with favorable gut microbiota and metabolite profiles in four human studies involving healthy adults. However, because participants largely followed vegetarian or vegan diets and no randomized controlled trials were included, the findings cannot prove that meditation alone reshapes the gut microbiome.

24 May 2026

A breakthrough molecular discovery could neutralize gluten and protect coeliac patients

A research project led by the Institute for Research in Nutrition and Food Safety (INSA) and the Faculty of Pharmacy and Food Sciences at the University of Barcelona, together with the Molecular Biology Institute of Barcelona (IBMB) of the CSIC (which stands for Consejo Superior de Investigaciones Científicas), has successfully designed and tested a gluten-degrading molecule that is a promising ally in the management of coeliac disease, an autoimmune disease whose symptoms are triggered by the consumption of gluten and other prolamins found in cereals.

14 May 2026

Gut microbes may reveal why diabetes raises heart disease risk

Integrated gut microbiome and plasma metabolomics profiling identified distinct microbial and metabolic signatures in people with T2DM and T2DM-CAD. In a small exploratory cohort, Bacteroides sp._CAG_875 and 12-ketoLCA emerged as candidate markers that may help distinguish diabetic patients with coronary complications, pending larger validation.

13 May 2026

Using AI to improve success rates of fecal microbiota transplants

MOZAIC leverages deep learning to optimize fecal microbiota transplantation, enhancing treatment efficacy through precise donor-recipient microbiome matching.

12 May 2026

Do repeated football head hits disrupt the gut microbiome?

A small exploratory study of collegiate football players found that non-concussive head impacts are correlationally linked to acute and season-long shifts in gut microbiome composition, with changes most pronounced 48–72 hours after significant impacts. However, most associations weakened after correction for multiple testing, and the authors stress the findings are preliminary and hypothesis-generating.

10 May 2026

AHA calls for lifelong brain health strategy to prevent cognitive decline

The AHA scientific statement calls for a life-course approach to brain health that integrates cognitive, emotional, behavioral, vascular, environmental, inflammatory, sleep, microbiome, and social factors. It highlights how early-life exposures, mental health, pollution, chronic inflammation, poor sleep, gut dysbiosis, and socioeconomic adversity may shape brain resilience and later-life cognitive decline.

29 Apr 2026

Specific intestinal fungi play role in the pathogenesis of MASLD and cardiovascular disease

Metabolic dysfunction-associated steatotic liver disease (MASLD) is an independent risk factor for cardiovascular disease (CVD). While gut bacteria have been linked to CVD, the role of intestinal fungi in subclinical coronary atherosclerosis (SCA) remains unclear.

23 Apr 2026

Scientists develop MIND approach to predict and reshape microbiomes

University of California San Diego researchers have developed a new tool for understanding and modifying any microbiome, including the human microbiome.

21 Apr 2026

Gut microbiome clues may help spot Parkinson’s disease in its earliest phase

Researchers found that a Parkinson’s disease-related gut microbiome pattern appears not only in people with diagnosed Parkinson’s, but also in some non-manifesting GBA1 variant carriers and a subset of healthy individuals. The findings suggest that gut microbiome changes may help flag people who are closer to Parkinson’s disease development, although longitudinal studies are still needed to confirm predictive value.

21 Apr 2026

Gut-liver changes drive foodborne infection severity in fatty liver disease

A research team led by the University of California, Irvine's Joe C. Wen School of Population & Public Health has uncovered a critical biological link explaining why individuals with metabolic dysfunction–associated steatotic liver disease (MASLD), or fatty liver disease, face significantly worse outcomes from certain foodborne infections.

15 Apr 2026

Higher mortality risk in IBS patients using antidepressants

Research indicates that antidepressant use in IBS is linked to a 35% higher risk of all-cause mortality, highlighting safety issues with long-term treatment.

13 Apr 2026

Cola may quickly lower pH inside orthodontic clear aligners and shift oral bacteria within hours

Researchers found that cola exposure quickly lowered pH and altered the microbiome on the inner surface of clear aligners, with the greatest disruption observed when aligners were removed before drinking and then reinserted. In this small 24-hour study, wearing aligners during exposure appeared less disruptive than removing them, though the authors said the mechanism still needs further study.

8 Apr 2026

Gut microbiota regulates intestinal epithelial cell function and plasticity

A research team led by scientists from the State University of Campinas (UNICAMP) in São Paulo, Brazil, has made significant progress in understanding the relationship between gut microbiota and intestinal cells.

7 Apr 2026

Can diet influence thyroid disease? A major review points to Mediterranean-style eating

This review found that thyroid health depends on more than iodine alone, with selenium, iron, zinc, vitamins, omega-3s, and overall eating patterns all shaping thyroid function and autoimmunity. It also concluded that Mediterranean-style diets are linked to more favorable thyroid outcomes, while unnecessary restrictive diets offer little benefit without a clear medical indication.

7 Apr 2026

How gut microbes may shape heart attack damage and recovery

This review argues that gut microbes and the metabolites they produce, especially SCFAs and TMAO, may shape how the heart responds to myocardial infarction through epigenetic pathways such as DNA methylation, histone modification, and non-coding RNAs. It also outlines potential intervention routes, including diet, probiotics, postbiotics, and metabolite-targeted therapies, while noting that much of the evidence remains translational and not yet clinically definitive.

6 Apr 2026

Gut microbiome changes improve memory in early cognitive decline

Research shows that modifying the gut microbiome can enhance cognitive performance and mitigate dementia risk, highlighting the gut-brain connection.

1 Apr 2026

Fiber supplement stabilizes blood sugar in gestational diabetes

Dietary fiber supplementation shows potential in managing blood sugar levels and preventing preterm births in pregnancies at risk for gestational diabetes.

1 Apr 2026

Why vaginal microbiota transplants aren’t working yet

Vaginal microbiota transplantation without antibiotics fails to restore microbiome balance, yet engraftment suggests avenues for enhancing treatment efficacy.

31 Mar 2026

How gut imbalance may drive obesity, diabetes, and heart disease

A new review argues that gut dysbiosis is closely linked to metabolic dysfunction through intertwined effects on inflammation, oxidative stress, gut barrier integrity, microbial metabolites, and epigenetic regulation. It also highlights microbiome-targeted strategies such as high-fiber diets, probiotics, prebiotics, postbiotics, exercise, and fecal microbiota transplantation as promising ways to support metabolic health.

30 Mar 2026

How do diet, smoking, alcohol, and stress reshape the female microbiome?

This review examines how modifiable lifestyle and environmental factors shape the female vaginal, gut, oral, and skin microbiomes, with diet, alcohol, smoking, obesity, stress, hygiene, physical activity, and sexual behaviours all linked to site-specific microbial shifts. It argues that understanding these patterns could help guide future female-focused prevention and intervention strategies.

30 Mar 2026