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Dual targeting strategy may improve treatment for resistant lung cancers

Findings from a study led by researchers at The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) support the potential of new therapies that could improve clinical outcomes for patients with squamous and adenocarcinoma non-small cell lung cancers (NSCLC) that don't respond to immunotherapy.

5 Mar 2026

Targeted mRNA delivery restores sperm production and fertility in infertile mice

Researchers have found that targeted delivery of messenger RNA (mRNA) can restore sperm production and fertility in genetically infertile male mice.

5 Mar 2026

Armored CAR T cells overcome tumor defenses in solid cancers

UCLA scientists have developed a next-generation CAR-T cell therapy that can overcome the immunosuppressive tumor microenvironment, a protective shield that tumors use to weaken immune cells, block their attack and fuel tumor growth.

4 Mar 2026

Enhancing myelination may help sustain therapeutic effects of psychedelic-assisted PTSD treatment

Post-traumatic stress disorder (PTSD) is not only characterized by strongly encoded traumatic memories, but also by disrupted coordination across brain networks.

4 Mar 2026

3D-printed scaffolds use shape memory to heal infected bone defects

Infected bone defects arise in conditions such as osteomyelitis and post-traumatic bone infections, where microbial persistence and immune imbalance prevent effective healing.

4 Mar 2026

Vaginal estrogen therapy is safe for young endometrial cancer survivors, study finds

Despite the increased incidence of endometrial cancer in younger women, there is limited research regarding the safety of local, low-dose vaginal estrogen therapy (ET) for survivors.

4 Mar 2026

Stem cells from human primary tooth pulp may help treat chronic-phase cerebral palsy

Cerebral palsy is a condition usually caused by brain damage before or during birth, resulting in impaired posture and movement.

4 Mar 2026

How are GLP-1 drugs reshaping treatment for obesity, diabetes, and heart disease?

A comprehensive Lancet review synthesizes evidence from major clinical trials showing that GLP-1 receptor agonists and next-generation incretin therapies deliver substantial weight loss while reducing cardiovascular and kidney risks. Emerging dual, triple, and oral agents may further expand treatment options and improve outcomes across obesity, type 2 diabetes, and related metabolic diseases.

3 Mar 2026

Experts identify safest and most effective diets for IBS management

This review in Nutrients evaluates the scientific evidence, clinical effectiveness, and safety of major dietary strategies for irritable bowel syndrome, including traditional advice, low-FODMAP, gluten-free, Mediterranean, and starch- and sucrose-reduced diets. It concludes that while the low-FODMAP diet has the strongest short-term evidence, no single approach fits all patients, and dietitian-led personalization is essential.

2 Mar 2026

Remote ischemic conditioning shields the heart from chemotherapy damage

Advances in cancer treatment mean that more people than ever are surviving the disease. However, some of the most effective anticancer drugs-a class of medicines called anthracyclines-can cause serious damage to the heart.

2 Mar 2026

Targeted PET/CT tracer improves early prediction of treatment response in rheumatoid arthritis patients

A new targeted PET/CT tracer can detect treatment response in rheumatoid arthritis patients in as little as four weeks, and potentially even at the start of treatment, according to new research published in The Journal of Nuclear Medicine.

27 Feb 2026

Acoziborole receives positive opinion for single-dose sleeping sickness treatment

The European Medicines Agency's Committee for Medicinal Products for Human Use (CHMP) has granted a positive opinion to Acoziborole Winthrop (acoziborole) as a single-dose oral treatment for both early- and advanced-stage gambiense sleeping sickness in adults as well as in adolescents 12 years and older weighing at least 40 kilograms.

27 Feb 2026

Fe₃O₄@mPEG-Ag nanoparticles offer non-antibiotic strategy to combat drug-resistant bacteria

A collaborative study by Guangzhou Medical University and South China University of Technology, published in BME Frontiers, introduces Fe₃O₄@mPEG-Ag nanoparticles (NPs) as a groundbreaking non-antibiotic strategy to combat drug-resistant bacteria.

27 Feb 2026

How physical strength and self-belief grow together in teens

Physical fitness and psychological resilience develop side by side during adolescence, a life stage that lays the foundation for adult health. Cardiorespiratory endurance, muscular strength, and agility are well-known predictors of cardiometabolic health, while self-efficacy, defined as the belief in one's ability to overcome challenges, shapes motivation, persistence, and coping strategies.

26 Feb 2026

Pomegranate’s hidden fiber-bound polyphenols significantly increase total antioxidant capacity

Researchers showed that pomegranate fruit extract contains substantial levels of non-extractable polyphenols bound within its fibre-rich matrix, significantly increasing its total measured antioxidant capacity. In human neuronal and astrocytic cell lines, the extract reduced hydrogen peroxide–induced oxidative stress, particularly in astrocytes, under in vitro conditions.

26 Feb 2026

Exploring the nanoscale: How AFM is transforming cosmetic science

Discover how Bruker is helping drive innovation in cosmetic science through advanced AFM techniques.

From Bruker BioAFM 26 Feb 2026

Meningococcal B vaccine fails to prevent gonorrhea, trial shows

Contrary to existing evidence from observational studies, the meningococcal B vaccine (4CMenB) has no effect on preventing the acquisition of gonorrhea, according to the results of the world's largest randomized control trial (RCT) into possible efficacy, conducted by Griffith University's Institute for Biomedicine and Glycomics and the Kirby Institute at UNSW Sydney.

25 Feb 2026

Next-generation CAR T therapy offers hope but faces clinical challenges

A new editorial perspective was published in Volume 17 of Oncotarget on February 20, 2026, titled "CAR-T therapy: Trailblazing CAR(ing) in cancer treatment."

25 Feb 2026

Opioids offer limited short-term relief for acute pain

The world's largest review of opioid pain relievers prescribed for acute pain found these medicines provide only small, short-term relief for some acute conditions and are ineffective for some others.

25 Feb 2026

SolasCure completes Phase II clinical trial, demonstrating accelerated healing with Aurase Wound Gel

SOLASCURE Ltd (SolasCure), a biotechnology company developing a novel treatment to transform chronic wound healing, today announced the successful completion of its second Phase II clinical trial, CLEANVLU2. The study demonstrated that its investigational product, Aurase Wound Gel (AWG), heals chronic wounds at a faster rate than current standard of care, providing clinical validation of its ability to deliver continuous enzymatic debridement while simultaneously activating wound healing.

24 Feb 2026

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Efficacy News and Research

Dual targeting strategy may improve treatment for resistant lung cancers

Targeted mRNA delivery restores sperm production and fertility in infertile mice

Armored CAR T cells overcome tumor defenses in solid cancers

Enhancing myelination may help sustain therapeutic effects of psychedelic-assisted PTSD treatment

3D-printed scaffolds use shape memory to heal infected bone defects

Vaginal estrogen therapy is safe for young endometrial cancer survivors, study finds

Stem cells from human primary tooth pulp may help treat chronic-phase cerebral palsy

How are GLP-1 drugs reshaping treatment for obesity, diabetes, and heart disease?

Experts identify safest and most effective diets for IBS management

Remote ischemic conditioning shields the heart from chemotherapy damage

Targeted PET/CT tracer improves early prediction of treatment response in rheumatoid arthritis patients

Acoziborole receives positive opinion for single-dose sleeping sickness treatment

Fe₃O₄@mPEG-Ag nanoparticles offer non-antibiotic strategy to combat drug-resistant bacteria

How physical strength and self-belief grow together in teens

Pomegranate’s hidden fiber-bound polyphenols significantly increase total antioxidant capacity

Exploring the nanoscale: How AFM is transforming cosmetic science

Meningococcal B vaccine fails to prevent gonorrhea, trial shows

Next-generation CAR T therapy offers hope but faces clinical challenges

Opioids offer limited short-term relief for acute pain

SolasCure completes Phase II clinical trial, demonstrating accelerated healing with Aurase Wound Gel

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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