Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

Different neurobiological pathways lead to expression of Alzheimer's disease

The amyloid cascade hypothesis of Alzheimer's disease (AD) posits that sticky aggregations or plaques of amyloid-beta peptides accumulate over time in the brain, triggering a series of events that ultimately result in the full-blown neurodegenerative disorder. The hypothesis has been a major driver of AD research for more than 20 years.

26 Jun 2015

Errors on memory and thinking tests may signal Alzheimer's 18 years before diagnosis

A new study suggests that errors on memory and thinking tests may signal Alzheimer's up to 18 years before the disease can be diagnosed. The research is published in the June 24, 2015, online issue of Neurology, the medical journal of the American Academy of Neurology.

26 Jun 2015

Study reveals differences in the way brain inflammation is expressed in people with Down syndrome, AD

Researchers at the University of Kentucky's Sanders-Brown Center on Aging have completed a study that revealed differences in the way brain inflammation -- considered a key component of AD-- is expressed in different subsets of patients, in particular people with Down syndrome (DS) and AD.

26 Jun 2015

University of Pittsburgh surgeon receives Anthony Cerami Award in Translational Medicine

The Feinstein Institute for Medical Research and Molecular Medicine announced today that the fourth Anthony Cerami Award in Translational Medicine will be conferred to Thomas E. Starzl, MD, PhD, professor of surgery at the University of Pittsburgh School of Medicine. The award is in recognition of his research in organ transplantation and alloengraftment mechanisms.

26 Jun 2015

Scientists redraw traditional brain map of language comprehension

For 140 years, scientists' understanding of language comprehension in the brain came from individuals with stroke. Based on language impairments caused by stroke, scientists believed a single area of the brain -- a hotdog shaped section in the temporal lobe of the left hemisphere called Wernicke's region -- was the center of language comprehension.

25 Jun 2015

Digital map of ageing brain could aid diagnosis of Alzheimer's disease, other neurodegenerative disorders

A digital map of the ageing brain could aid the diagnosis of Alzheimer's disease and other neurodegenerative disorders in older people, a study suggests.

24 Jun 2015

High-fat, high-sugar diet can cause bacterial changes that appear related to loss of 'cognitive flexibility'

A study at Oregon State University indicates that both a high-fat and a high-sugar diet, compared to a normal diet, cause changes in gut bacteria that appear related to a significant loss of "cognitive flexibility," or the power to adapt and adjust to changing situations.

23 Jun 2015

Drug discovery experts receive £3m to find new treatments for Alzheimer's disease

Funding worth nearly half a million pounds will unite academics at the University of Southampton with drug discovery experts at the medical research charity MRC Technology, to target the immune system in the hunt for new treatments for Alzheimer's disease.

19 Jun 2015

WSU research provides new strategies for prevention, treatment of obesity

Washington State University scientists have shown that berries, grapes and other fruits convert excess white fat into calorie-burning "beige" fat, providing new strategies for the prevention and treatment of obesity.

19 Jun 2015

Professor Tiago H. Falk receives CMBES Early Career Achievement Award

Professor Tiago H. Falk of the INRS Énergie Matériaux Télécommunications Research Centre has received the Canadian Medical and Biological Engineering Society (CMBES) Early Career Achievement Award in recognition of the outstanding scientific contributions the young researcher has made over the past five years.

19 Jun 2015

Discovery provides clue to long-held mystery about how animals' internal compasses function

A team of scientists and engineers at The University of Texas at Austin has identified the first sensor of the Earth's magnetic field in an animal, finding in the brain of a tiny worm a big clue to a long-held mystery about how animals' internal compasses work.

18 Jun 2015

Simple test could help identify genetically inherited risk for prostate cancer

Men with an elevated, genetically inherited risk for prostate cancer could be routinely identified with a simple blood or urine test, scientists at UC San Francisco and Kaiser Permanente Northern California have concluded, potentially paving the way to better or earlier diagnosis.

18 Jun 2015

ABC Medical Home program achieves significant health improvement for people with depression

The Aging Brain Care Medical Home, a novel population health management program implemented in the homes of older adults achieves significant health improvement for individuals with depression and also substantial stress reduction in family caregivers of dementia patients, according to a new study by investigators from the Regenstrief Institute, Indiana University Center for Aging Research and Eskenazi Health.

17 Jun 2015

Women with significant depressive symptoms have lower levels of klotho hormone

Women under chronic stress have significantly lower levels of klotho, a hormone that regulates aging and enhances cognition, researchers at UC San Francisco have found in a study comparing mothers of children on the autism spectrum to low-stress controls.

17 Jun 2015

Research explores screening methods, clinical care for patients with Alzheimer's and all forms of dementia

Every 67 seconds someone is the United States develops Alzheimer's disease or some form of dementia. It's the sixth leading cause of death in the U.S. and it's the only cause of death in the top 10 in America that cannot be prevented, cured or slowed. This month, as the nation observes "Alzheimer's & Brain Awareness Month," James E. Galvin, M.D., M.P.H., one of the most prominent neuroscientists in the country, is at the helm of cutting-edge research, screening methods and clinical care for all forms of dementia and cognitive impairments as well as neurodegenerative diseases like Alzheimer's disease and Parkinson's disease.

16 Jun 2015

Researchers find lymphatic vessels in the central nervous system

In a study published in The Journal of Experimental Medicine, researchers working at the Wihuri Research Institute and the University of Helsinki report a surprising finding that challenges current anatomy and histology textbook knowledge: Lymphatic vessels are found in the central nervous system where they were not known to exist.

16 Jun 2015

UIC study shows that brain cell density remains constant in normal aging

New, ultra-high-field magnetic resonance images (MRI) of the brain by researchers at the University of Illinois at Chicago provide the most detailed images to date to show that while the brain shrinks with age, brain cell density remains constant.

14 Jun 2015

Early neuronal lysosomal dysfunction could help predict AD

Blood levels of altered lysosomal proteins may help detect preclinical Alzheimer’s disease, researchers report.

12 Jun 2015

Physical activities may not protect against underlying markers for Alzheimer's disease

While participating in physical activities such as bike riding, dancing, walking and gardening and mentally stimulating activities such as crosswords and reading may reduce the risk of Alzheimer's disease, they may not do so by affecting the underlying markers for the disease, according to a study published in the June 10, 2015, online issue of Neurology, the medical journal of the American Academy of Neurology.

11 Jun 2015

Specialized brain proteins may be detected in the blood samples of individuals with Alzheimer's disease

Specialized brain proteins that are involved in the removal of damaged nerve cell materials may be detected in the blood of people who were diagnosed with mild cognitive impairment or dementia due to Alzheimer's disease.

11 Jun 2015

Alzheimer's Disease News and Research

Further Reading

Different neurobiological pathways lead to expression of Alzheimer's disease

Errors on memory and thinking tests may signal Alzheimer's 18 years before diagnosis

Study reveals differences in the way brain inflammation is expressed in people with Down syndrome, AD

University of Pittsburgh surgeon receives Anthony Cerami Award in Translational Medicine

Scientists redraw traditional brain map of language comprehension

Digital map of ageing brain could aid diagnosis of Alzheimer's disease, other neurodegenerative disorders

High-fat, high-sugar diet can cause bacterial changes that appear related to loss of 'cognitive flexibility'

Drug discovery experts receive £3m to find new treatments for Alzheimer's disease

WSU research provides new strategies for prevention, treatment of obesity

Professor Tiago H. Falk receives CMBES Early Career Achievement Award

Discovery provides clue to long-held mystery about how animals' internal compasses function

Simple test could help identify genetically inherited risk for prostate cancer

ABC Medical Home program achieves significant health improvement for people with depression

Women with significant depressive symptoms have lower levels of klotho hormone

Research explores screening methods, clinical care for patients with Alzheimer's and all forms of dementia

Researchers find lymphatic vessels in the central nervous system

UIC study shows that brain cell density remains constant in normal aging

Early neuronal lysosomal dysfunction could help predict AD

Physical activities may not protect against underlying markers for Alzheimer's disease

Specialized brain proteins may be detected in the blood samples of individuals with Alzheimer's disease

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