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New method for detecting inflammation could revolutionize disease diagnosis

Nearly every disease has an inflammatory component, but blood tests can't pinpoint inflammation in specific organs or tissues in the human body.

6 Feb 2025

MaxCyte® acquires SeQure Dx to broaden cell engineering offerings with on-target and off-target editing assessments

MaxCyte, Inc., a leading, cell-engineering focused company providing solutions to advance the discovery, development and commercialization of next-generation cell therapeutics announced today the acquisition of SeQure Dx, a market leader of on-target and off-target editing assessment services for cell and gene therapies.

From MaxCyte, Inc. 6 Feb 2025

New drug class may help alleviate IBS symptoms by targeting the central nervous system

Irritable bowel syndrome (IBS) is a common digestive disorder that affects the intestine, causing symptoms such as abdominal pain, bloating, gas, and changes in bowel habits, including diarrhea, constipation, or both.

5 Feb 2025

CN Bio launches physioMimix DILI assay kit: Human 24, for enhanced preclinical toxicology testing

CN Bio, a leading provider of Organ-on-a-chip (OOC) Systems and solutions that accelerate drug discovery and development workflows, today announced the launch of its PhysioMimix® DILI assay kit: Human 24.

5 Feb 2025

Researchers develop T cell growth method that enhances cancer-fighting ability in melanoma model

Findings indicate that altering glucose metabolism in T cells boosts their therapeutic potential against melanoma, paving the way for improved immunotherapies.

31 Jan 2025

Mayo Clinic researchers create organoid models for uveal melanoma study

Mayo Clinic researchers have developed organoid models to study uveal melanoma, one of the most common types of eye cancer in adults.

29 Jan 2025

New compound Z526 combats cancer-associated cachexia in preclinical models

In a recent study, researchers demonstrated that Z526, a novel dithiocarbamate-like compound, mitigates cancer-associated cachexia (CAC) both in vitro and in vivo.

29 Jan 2025

Schrödinger selects Sapio Sciences to enhance in silico drug discovery from plasmid to structure

Sapio Sciences, the science-aware™ lab informatics platform, today announced that Schrödinger, a global leader in computational chemistry, has adopted the Sapio Platform to improve data management, enhance lab efficiency, and accelerate the discovery of novel molecules.

From Sapio Sciences 29 Jan 2025

New treatment identified for peripheral nerve sheath tumors

A multicenter collaboration led by the Bellvitge Biomedical Research Institute (IDIBELL) - Institut Català d'Oncologia (ICO) and the Germans Trias i Pujol Research Institute (IGTP) identified a potential new treatment for an aggressive sarcoma arising in the nerves.

28 Jan 2025

New delivery system could improve the effectiveness of peptide-based cancer vaccines

Researchers at the Terasaki Institute for Biomedical Innovation have developed an innovative delivery system that could significantly improve the effectiveness of peptide-based cancer vaccines, according to a new study published in Advanced Functional Materials.

28 Jan 2025

$Combined therapy could revolutionize the prevention of osteoporosis fractures$

Combined therapy could revolutionize the prevention of osteoporosis fractures

Osteoporosis is a disease in which bone resorbs faster than it is formed, gradually weakening its structure over time and leading to fractures.

28 Jan 2025

Establishing common nomenclature for mitochondria transfer and transplantation

Most animal, plant and fungal cells contain organelles called mitochondria. These descendants of a primordial bacterial endosymbiont still preserve distinct genes and are known for their ability to create ATP as chemical energy.

27 Jan 2025

New nanosystem offers hope for improved diagnosis and treatment of tongue cancer

A pioneering study has unveiled the Au-HN-1 nanosystem, a cutting-edge approach that promises to transform the diagnosis and treatment of tongue squamous cell carcinoma (TSCC).

27 Jan 2025

Breakthrough gene discovery offers new hope for medulloblastoma therapy

Scientists at The Hospital for Sick Children (SickKids) have identified a key gene that could lead to next-generation treatments for medulloblastoma, the most common malignant brain tumor in children.

24 Jan 2025

NUS researchers develop DNA barcoded nanoparticles for targeted cancer therapy

A team of researchers from the National University of Singapore (NUS) has developed a novel method to enhance the precision of cancer treatment using gold nanoparticles tagged with DNA barcodes.

24 Jan 2025

Researchers elucidate the significance of birth in neural stem cell maintenance

A research group led by Kazunobu Sawamoto, a professor at Nagoya City University and National Institute for Physiological Sciences, and Koya Kawase, a pediatric doctor at Nagoya City University Hospital, has elucidated the significance of birth in the maintenance of neural stem cells (NSCs).

24 Jan 2025

Research develops framework to compare lab, AI, and simulation data

The successful and safe delivery of therapeutics relies on understanding how easily drugs can pass through biological barriers which protect cells.

24 Jan 2025

Researchers identify ferroptosis as driver of osteocyte death in melanoma metastasis

Melanoma, one of the most aggressive forms of skin cancer, often metastasizes to bones, causing severe bone loss, an increased risk of fractures, and significant pain.

23 Jan 2025

New approach to treating ependymoma with leukemia drug

Rakesh Jain PhD, Director of the E.L. Steele Laboratories for Tumor Biology at Massachusetts General Hospital and A. Werk Cook Professor of Radiation Oncology at Harvard Medical School, is senior author of a new study in PNAS, Targeting EPHB2/ABL1 Restores Anti-Tumor Immunity in Preclinical Models of Ependymoma.

23 Jan 2025

Microplastics in the bloodstream may pose hidden risks to brain health

Trapped immune cells laden with microplastics starve the brain of oxygen—mouse study links vascular blockages to memory loss and motor deficits, with lingering risks even after symptoms fade.

23 Jan 2025

in vivo News and Research

New method for detecting inflammation could revolutionize disease diagnosis

MaxCyte® acquires SeQure Dx to broaden cell engineering offerings with on-target and off-target editing assessments

New drug class may help alleviate IBS symptoms by targeting the central nervous system

CN Bio launches physioMimix DILI assay kit: Human 24, for enhanced preclinical toxicology testing

Researchers develop T cell growth method that enhances cancer-fighting ability in melanoma model

Mayo Clinic researchers create organoid models for uveal melanoma study

New compound Z526 combats cancer-associated cachexia in preclinical models

Schrödinger selects Sapio Sciences to enhance in silico drug discovery from plasmid to structure

New treatment identified for peripheral nerve sheath tumors

New delivery system could improve the effectiveness of peptide-based cancer vaccines

Combined therapy could revolutionize the prevention of osteoporosis fractures

Establishing common nomenclature for mitochondria transfer and transplantation

New nanosystem offers hope for improved diagnosis and treatment of tongue cancer

Breakthrough gene discovery offers new hope for medulloblastoma therapy

NUS researchers develop DNA barcoded nanoparticles for targeted cancer therapy

Researchers elucidate the significance of birth in neural stem cell maintenance

Research develops framework to compare lab, AI, and simulation data

Researchers identify ferroptosis as driver of osteocyte death in melanoma metastasis

New approach to treating ependymoma with leukemia drug

Microplastics in the bloodstream may pose hidden risks to brain health

eBook: Using iPSCs models for human disease research and drug discovery eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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