Efficacy News and Research

RSS

Escape from vaccine-induced immunity likely contributed to rapid rise of SARS-CoV-2 Omicron

Researchers investigate whether the SARS-CoV-2 Omicron variant is more likely to infect vaccinated individuals than the SARS-CoV-2 Delta variant.

30 Jan 2022

Damon Runyon Cancer Research Foundation announces newest cohort of Fellows and Breakthrough Scientists

The Damon Runyon Cancer Research Foundation has announced its newest cohort of Damon Runyon Fellows, 13 outstanding postdoctoral scientists conducting basic and translational cancer research in the laboratories of leading senior investigators.

29 Jan 2022

Study provides atomistic level insight into target residence time of small molecule kinase inhibitors

When a drug molecule binds to its target protein, it stays bound for some time before eventually unbinding the target. The actual time how long a drug molecule resides bound to its target varies among compounds.

29 Jan 2022

Researchers develop a real-time method for projecting COVID-19 quarantine housing needs

It's difficult to plan ahead when SARS-CoV-2, the virus that causes COVID-19, is so unpredictable. But, there is now a straightforward method for predicting one of the resources needed to slow the spread of COVID-19 in communities.

28 Jan 2022

Novel “prime and spike” vaccine strategy leverages existing immunity generated by primary COVID-19 vaccination

Scientists from Yale University, USA, have recently developed an intranasal spike boosting vaccine that induces robust mucosal immunity in the respiratory tract,

28 Jan 2022

Reduced neutralization against Omicron variant in fully immunized adolescents with BNT162b2 vaccine

Researchers compare the humoral immune response in adolescents and adults after being completely immunized with the Pfizer BNT162b2 vaccine.

28 Jan 2022

Study demonstrates minimally invasive, aerosolized vaccine candidate to combat SARS-CoV-2

This study showed inhalable Covid-19 mimetic particle carriers as potential, versatile, aerosolizable COVID-19 vaccine candidates if worked on with continued optimization and refinement.

28 Jan 2022

E406W mutation on SARS-CoV-2 RBD escapes monoclonal antibody cocktail-mediated neutralization

Researchers look to better understand the molecular basis of E406W-mediated escape from the REGEN-COV cocktail and cilgavimab.

28 Jan 2022

Intranasal interferon-λ treatment protects mice against SARS-CoV-2 Beta and Omicron variants

Researchers investigate the possible efficacy of IFN-λ in the context of SARS-CoV-2 infection in mice.

28 Jan 2022

Photobiomodulation may accelerate the healing of skin damage from radiation therapy

Light therapy may accelerate the healing of skin damage from radiation therapy by up to 50%, according to a recent University at Buffalo-led study.

27 Jan 2022

Rising NO2 pollution levels in urban areas may lead to new child asthma cases

Reducing air pollution should be a crucial part of health strategies for children, as nitrogen dioxide (NO2) — a harmful pollutant emitted from burning fossil fuels — may lead to nearly 2 million new child asthma cases a year, research suggests.

27 Jan 2022

Early-stage alveolar epithelial cell necrosis linked to COVID-19-induced acute respiratory distress syndrome

A new study analyzed whether alveolar epithelial cell necrosis at an early stage SARS-CoV-2 infection and subsequent releases of damage-associated molecular patterns could aggravate COVID-19-associated acute respiratory distress syndrome.

27 Jan 2022

Scientists identify immunogens that can elicit antibody responses against multiple SARS-CoV-2 variants

In a new study, researchers identified conserved sites in the SARS-CoV-2 spike protein using structural and sequence data, and then combined the results with existing deep mutational scanning data to design six antigens that can offer protection against significant immune escape mutations in the SARS-CoV-2 receptor-binding domain.

27 Jan 2022

Effects of multi-nutrient supplementation on COVID-19 severity in elderly patients

In a new study, researchers analyzed the effects of multi-nutrient supplementation on SARS-CoV-2 vaccine efficacy and the overall improvement of respiratory and muscle function in elderly COVID-19 patients.

27 Jan 2022

Impact of SARS-CoV-2 testing behavior on observational studies of vaccine efficiency

A new study investigated the differences in SARS-CoV-2 testing behavior exhibited by vaccinated and unvaccinated individuals.

27 Jan 2022

Evaluating the effectiveness of vaccination on the case fatality rate for COVID-19 infection

A recent study was published where CFR was assessed for COVID-19 vaccine effectivity

27 Jan 2022

French project takes an extra step in the development of nasal vaccine candidate against COVID-19

The development of a protein vaccine candidate for nasal administration has taken another step. Led by the BioMAP research team, from the Infectiology and Public Health (ISP) joint research unit run by INRAE and the Université de Tours, this project, supported by the Ministry of Higher Education, Research and Innovation, and accompanied by the ANRS | Maladies infectieuses émergentes, is moving up a gear.

27 Jan 2022

Immunosuppressed patients can benefit from COVID-19 booster vaccination, study shows

Patients under immunosuppressive therapy, who do not respond to primary COVID-19 vaccination, have an increased risk for severe COVID-19 disease courses. Until now, it was not clear whether those patients at risk can benefit from an additional booster vaccination.

26 Jan 2022

England returns to Plan A following the success of booster rollout and falling Omicron infections

From 00:01 on Thursday 27th January England returned to Plan A measures following the huge success of the vaccination program and falling Omicron infections.

26 Jan 2022

Macromolecular gel with therapeutic payload could halt or slow post-traumatic osteoarthritis

Osteoarthritis affects over 32 million Americans, levying a huge cost on society. Unfortunately, other than analgesics, no pharmaceutical therapy exists that can slow or halt disease progression of a major subset of OA: post-traumatic osteoarthritis (PTOA).

26 Jan 2022

Efficacy News and Research

Escape from vaccine-induced immunity likely contributed to rapid rise of SARS-CoV-2 Omicron

Damon Runyon Cancer Research Foundation announces newest cohort of Fellows and Breakthrough Scientists

Study provides atomistic level insight into target residence time of small molecule kinase inhibitors

Researchers develop a real-time method for projecting COVID-19 quarantine housing needs

Novel “prime and spike” vaccine strategy leverages existing immunity generated by primary COVID-19 vaccination

Reduced neutralization against Omicron variant in fully immunized adolescents with BNT162b2 vaccine

Study demonstrates minimally invasive, aerosolized vaccine candidate to combat SARS-CoV-2

E406W mutation on SARS-CoV-2 RBD escapes monoclonal antibody cocktail-mediated neutralization

Intranasal interferon-λ treatment protects mice against SARS-CoV-2 Beta and Omicron variants

Photobiomodulation may accelerate the healing of skin damage from radiation therapy

Rising NO2 pollution levels in urban areas may lead to new child asthma cases

Early-stage alveolar epithelial cell necrosis linked to COVID-19-induced acute respiratory distress syndrome

Scientists identify immunogens that can elicit antibody responses against multiple SARS-CoV-2 variants

Effects of multi-nutrient supplementation on COVID-19 severity in elderly patients

Impact of SARS-CoV-2 testing behavior on observational studies of vaccine efficiency

Evaluating the effectiveness of vaccination on the case fatality rate for COVID-19 infection

French project takes an extra step in the development of nasal vaccine candidate against COVID-19

Immunosuppressed patients can benefit from COVID-19 booster vaccination, study shows

England returns to Plan A following the success of booster rollout and falling Omicron infections

Macromolecular gel with therapeutic payload could halt or slow post-traumatic osteoarthritis

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Latest News