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HyFly research project aims to break chains of infection and prevent pandemics

Global air travel isn't restricted to people and goods - infectious agents, too, can make their way on board as unwelcome passengers and travel great distances within a matter of hours.

1 Oct 2018

CNL, TRIUMF team up to enable revolutionary cancer treatment

TRIUMF, Canada's particle accelerator center, and Canadian Nuclear Laboratories, Canada's premier nuclear science and technology organization, are pleased to announce that they have agreed to pursue a strategic partnership around the commercial production of Actinium-225, a rare medical isotope that has the potential to serve as the basis of new ground-breaking cancer treatments.

28 Sep 2018

Daily exercise facilitates elimination of toxic proteins from muscles

A study published in Scientific Reports by researchers at the University of São Paulo in Brazil, in partnership with colleagues in the United States and Norway, shows that the lack of muscle stimulus results in a buildup of inadequately processed proteins in muscle cells and consequently leads to muscle weakness or wasting.

27 Sep 2018

FLX Bio treats first patient in its Phase 1/2 clinical trial of FLX475 for treating various advanced cancers

FLX Bio, Inc., a clinical-stage, biopharmaceutical company focused on the development of oral small-molecule drugs that target drivers of cancer and other immune-related disorders, today announced that the first patient has been treated in its Phase 1/2 clinical trial of FLX475 in patients with various advanced cancers. FLX475 is an oral, small molecule CCR4 antagonist that selectively inhibits migration of regulatory T cells into the tumor microenvironment.

27 Sep 2018

Study uncovers new molecule involved in regeneration of acute liver wounds

A new study from researchers of CEDOC-NOVA Medical School|Faculdade de Ciências Médicas and Instituto Gulbenkian de Ciência, led by Maria Paula Macedo and Carlos Penha-Gonçalves, respectively, published in Hepatology Communications, showed that a molecule CD26/DPP-4 is involved in the regeneration of acute liver wounds and is a promising biomarker for hepatic disease.

26 Sep 2018

New EU project aims to learn more about hormone-disrupting chemicals

Hormone-disrupting chemicals in our environment can affect early neurodevelopment in children, but little is known about the exact mechanisms for this interference. A new EU funded research project, coordinated from Karolinska Institutet, now aims to learn more and to develop better screening and testing tools.

26 Sep 2018

Risk-profiling can help improve preventive measures against HIV

That men who have sex with men run a greater risk of HIV than others has been known since the virus was discovered. However a thesis from Karolinska Institutet now shows that it is a small sub-group of these men who account for the greater part of the risk increase.

26 Sep 2018

Urine exRNA may be source of biomarkers for muscular dystrophy

Massachusetts General Hospital researchers have found that extracellular RNA in urine may be a source of biomarkers for the two most common forms of muscular dystrophy, noninvasively providing information about whether therapeutic drugs are having the desired effects on a molecular level.

26 Sep 2018

Study reveals structure of potential drug target in neurological conditions

Researchers at Van Andel Research Institute (VARI) have revealed the atomic-level structure of a protein that could serve as a promising new drug target for the treatment of neurological conditions such as bipolar disorder and Alzheimer’s disease.

25 Sep 2018

Cerevance starts dosing in Phase I clinical trial of CVN424 for treatment of Parkinson's disease

Cerevance, a clinical-stage drug discovery and development company focused on brain diseases, today announced the start of dosing in a Phase I first-in-human clinical trial of CVN424, an oral compound being developed for symptomatic treatment of Parkinson's disease.

25 Sep 2018

Researchers develop molecule that makes cancer cells sensitive to radiotherapy

Researchers from Karolinska Institutet and Kancera AB have developed a molecule that makes cancer cells sensitive to radiotherapy. In a study published in Nature Communications, the researchers describe a new way to block cancer cells' ability to repair their DNA and thus stop the survival of cancer cells.

25 Sep 2018

Researchers find molecule that halts, reverts neurodegeneration caused by Parkinson's disease

The small SynuClean-D molecule interrupts the formation of the alpha-synuclein amyloid fibers responsible for the onset of Parkinson's disease, and reverts the neurodegeneration caused by the disease.

25 Sep 2018

TU Wien develops new remedy for celiac disease

Celiac disease is a fairly common disease, affecting one to two percent of the European population. It is expressed as a hypersensitivity to gluten, a protein found in cereals such as wheat, barley or rye.

24 Sep 2018

Lumos acquires license for LUM-201 drug that promotes secretion of growth hormone

Lumos Pharma, Inc., a clinical stage biopharmaceutical company focused on development and commercialization of therapeutics for rare and neglected diseases, today announced that it has acquired the license for LUM-201, an investigational orally administered small molecule that promotes secretion of growth hormone from the pituitary gland, from Ammonett Pharma LLC.

24 Sep 2018

ADCETRIS drug receives approval in Japan as frontline treatment option for Hodgkin lymphoma

Seattle Genetics, Inc. today announced that its collaborator, Takeda Pharmaceutical Company Limited, has received approval from the Japanese Ministry of Health, Labour and Welfare for ADCETRIS (brentuximab vedotin) in combination with doxorubicin, vinblastine and dacarbazine as a frontline treatment option for CD30-positive Hodgkin lymphoma patients in Japan.

24 Sep 2018

Columbia University announces winners of 2018 Louisa Gross Horwitz Prize

Columbia University has decided to award the Louisa Gross Horwitz Prize 2018.

24 Sep 2018

Overlooked immune cells could play a key role in cancer immunotherapy, claims new study

Cancer immunotherapy is a relatively new method of treating cancer and has succeeded with some refractory tumors. However, it doesn’t always work, why not?

21 Sep 2018

CHMP provides positive opinion to Cabometyx for previously-treated patients with hepatocellular carcinoma

Ipsen announced today that the Committee for Medicinal Products for Human Use, the scientific committee of the European Medicines Agency, provided a positive opinion for Cabometyx (cabozantinib) as a monotherapy for the treatment of hepatocellular carcinoma in adults who have been previously treated with sorafenib.

21 Sep 2018

New research finds that MHC-II molecules have more influence on tumors than MHC-I

Cancer immunotherapy -- efforts to boost a patient's own immune system, allowing it to better fight cancer cells on its own -- has shown great promise for some previously intractable cancers.

21 Sep 2018

New naturally occurring antibiotic found effective against Mycobacterium tuberculosis

A naturally occurring antibiotic called kanglemycin A is effective against Mycobacterium tuberculosis, the bacteria that cause tuberculosis, even in drug-resistant strains, according to an international team of researchers who used chemistry, molecular biology, microbiology, and X-ray crystallography to show how the compound maintains its activity.

21 Sep 2018

Molecule News and Research

HyFly research project aims to break chains of infection and prevent pandemics

CNL, TRIUMF team up to enable revolutionary cancer treatment

Daily exercise facilitates elimination of toxic proteins from muscles

FLX Bio treats first patient in its Phase 1/2 clinical trial of FLX475 for treating various advanced cancers

Study uncovers new molecule involved in regeneration of acute liver wounds

New EU project aims to learn more about hormone-disrupting chemicals

Risk-profiling can help improve preventive measures against HIV

Urine exRNA may be source of biomarkers for muscular dystrophy

Study reveals structure of potential drug target in neurological conditions

Cerevance starts dosing in Phase I clinical trial of CVN424 for treatment of Parkinson's disease

Researchers develop molecule that makes cancer cells sensitive to radiotherapy

Researchers find molecule that halts, reverts neurodegeneration caused by Parkinson's disease

TU Wien develops new remedy for celiac disease

Lumos acquires license for LUM-201 drug that promotes secretion of growth hormone

ADCETRIS drug receives approval in Japan as frontline treatment option for Hodgkin lymphoma

Columbia University announces winners of 2018 Louisa Gross Horwitz Prize

Overlooked immune cells could play a key role in cancer immunotherapy, claims new study

CHMP provides positive opinion to Cabometyx for previously-treated patients with hepatocellular carcinoma

New research finds that MHC-II molecules have more influence on tumors than MHC-I

New naturally occurring antibiotic found effective against Mycobacterium tuberculosis

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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