B Cell News and Research

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Stress hormones may silence crucial neuronal genes through specific RNA molecules

What if the brain's response to stress could be read not in fleeting neurotransmitter bursts, but in the quieting of genes deep inside chromatin? Researchers at the University of Alabama at Birmingham have now shown that stress hormones may silence crucial neuronal genes through an unexpected class of RNA molecules that operate not by encoding proteins, but by reshaping the genome's architecture.

4 Nov 2025

NIH-funded study investigates signals mediating the earliest stages of cancer development

The same cellular renewal that keeps our bodies healthy might also fuel the growth of cancer. A UC Merced biologist has found that the brain could hold the key to stopping it.

4 Nov 2025

Study reveals how "P bodies" heavily influence a cell's fate

How do stem cells know what to become? Nearly three decades after scientists isolated the first human embryonic stem cells, researchers are still working hard to understand precisely how a single, undifferentiated cell can become any one of the roughly 200 cell types that make up the human body.

4 Nov 2025

New approach harnesses tumor's own machinery to produce immune-stimulating molecules

By stimulating cancer cells to produce a molecule that activates a signaling pathway in nearby immune cells, MIT researchers have found a way to force tumors to trigger their own destruction.

3 Nov 2025

Hijacking cellular machinery within cancer cells to promote antitumor immunity

Investigators from Mass General Brigham have developed a way to promote antitumor immunity by hijacking cellular machinery within cancer cells.

3 Nov 2025

Mapping how the heart heals after a heart attack

Over the course of evolution, the human heart has largely lost its ability to regenerate. Our distant ancestors were not afflicted by heart attacks - a condition that emerged primarily with modern lifestyles marked by poor diet, obesity, and other cardiovascular risk factors.

3 Nov 2025

NIH grant supports research on how the immune system responds to serious eye infections

New research that sheds light on how the immune system responds to serious eye infections is underway at Wayne State University, supported by a $2.3 million federal grant from the National Eye Institute of the National Institutes of Health (NIH).

3 Nov 2025

Kids First DRC releases 37th pediatric study on rare childhood cancers

The Gabriella Miller Kids First Data Resource Center (Kids First DRC) has released its 37th pediatric research study, available in the Kids First Data Resource Portal.

3 Nov 2025

How walnuts combat inflammation and oxidative stress in the body

This review in Food Science & Nutrition synthesizes evidence showing that walnuts (Juglans regia L.) exert potent antioxidant, anti-inflammatory, apoptosis-regulatory, and immunomodulatory effects through bioactive compounds influencing mitochondrial, cytokine, and redox pathways.

3 Nov 2025

Study highlights bioengineered models as key to early cancer detection

Scientists are exploring leading-edge technologies that could transform how cancer is studied, detected and treated by catching it earlier, when it's more treatable and survival rates are highest.

3 Nov 2025

Johns Hopkins study reveals enzyme that shields neurons from oxidative stress

New research from Johns Hopkins Medicine shows that the enzyme biliverdin reductase A (BVRA) plays a direct protective role against oxidative stress in neurons, independent of its role producing the yellow pigment bilirubin.

3 Nov 2025

Large-scale foundation model reconstructs how cells interact within tissues

Researchers at Helmholtz Munich and the Technical University of Munich (TUM) have developed Nicheformer, the first large-scale foundation model that integrates single-cell analysis with spatial transcriptomics.

3 Nov 2025

Urolithin A recharges aging immune cells and boosts mitochondrial fitness in midlife adults

Urolithin A, a natural postbiotic known to trigger mitophagy, rejuvenated key immune cell functions in healthy middle-aged adults after 28 days. The trial showed a shift toward a youthful, energy-efficient CD8⁺ T-cell profile and enhanced bacterial clearance without inflammatory side effects.

3 Nov 2025

Scientists create detailed single-cell map of the developing human brain

Scientists from Duke-NUS Medical School and their collaborators have created one of the most comprehensive single cell maps of the developing human brain. The atlas captures nearly every cell type, their genetic fingerprints, and how they grow and interact.

3 Nov 2025

Researchers develop a versatile tool for controlling gene activity

Investigators at Weill Cornell Medicine have developed a versatile and non-toxic technology for controlling the activity of any gene in a cell. Such "gene-switch" tools allow scientists to "turn on" or "turn off" a target gene to study how it works, model diseases and design new therapies.

3 Nov 2025

Researchers identify new molecular switch involved in programmed cell death

In the fight against disease, programmed cell death – also known as apoptosis – is a key protective function of the body. It breaks down cells that are damaged or have undergone dangerous changes.

3 Nov 2025

Nuclera expands access to eProtein Discovery for APAC customers with distributor agreement in Australia and New Zealand

Nuclera, the biotechnology company accelerating drug discovery by providing rapid, easy access to functional proteins through its benchtop eProtein Discovery™ System, today announced that it has signed a partnership with Solve Scientific Australia, a life science research solutions provider.

3 Nov 2025

New research reveals how human astroviruses enter the body

Human astroviruses are a leading viral cause of the stomach bug-think vomiting, diarrhea, and fever. It often impacts young children and older adults, leading to vicious cycles of sickness and malnutrition, particularly for those in low and middle income countries.

3 Nov 2025

Scientists explore why black rice deserves a bigger place in modern diets

Researchers reviewed the nutritional composition, therapeutic benefits, and industrial uses of black rice, highlighting its potential as a functional food. The study highlights the role of black rice in managing blood sugar, cholesterol, and inflammation, while also advocating for more robust human trials and sustainable cultivation methods.

2 Nov 2025

Scientists uncover new obesity genes that reshape understanding of weight and disease risk

Researchers identified five previously unknown genes linked to obesity by analyzing rare protein-truncating variants across six ancestries. The study reveals how rare and common genetic factors combine to influence BMI and related diseases like diabetes and heart failure.

2 Nov 2025

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B Cell News and Research

Stress hormones may silence crucial neuronal genes through specific RNA molecules

NIH-funded study investigates signals mediating the earliest stages of cancer development

Study reveals how "P bodies" heavily influence a cell's fate

New approach harnesses tumor's own machinery to produce immune-stimulating molecules

Hijacking cellular machinery within cancer cells to promote antitumor immunity

Mapping how the heart heals after a heart attack

NIH grant supports research on how the immune system responds to serious eye infections

Kids First DRC releases 37th pediatric study on rare childhood cancers

How walnuts combat inflammation and oxidative stress in the body

Study highlights bioengineered models as key to early cancer detection

Johns Hopkins study reveals enzyme that shields neurons from oxidative stress

Large-scale foundation model reconstructs how cells interact within tissues

Urolithin A recharges aging immune cells and boosts mitochondrial fitness in midlife adults

Scientists create detailed single-cell map of the developing human brain

Researchers develop a versatile tool for controlling gene activity

Researchers identify new molecular switch involved in programmed cell death

Nuclera expands access to eProtein Discovery for APAC customers with distributor agreement in Australia and New Zealand

New research reveals how human astroviruses enter the body

Scientists explore why black rice deserves a bigger place in modern diets

Scientists uncover new obesity genes that reshape understanding of weight and disease risk

Using single B cell screening to boost antibody discovery eBook

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