Insulin News and Research

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Insulin is a hormone that is needed to convert glucose, starches and other food into energy needed for daily life. Insulin allows cells to use glucose for fuel and is secreted by beta cells in the islets of Langerhans. The release of insulin from the pancreas is stimulated by increased blood glucose, vagal nerve stimulation, and other factors. Insulin is obtained from various animals and available in a variety of preparations. Commercial insulin preparations differ in a number of ways, including differences in the animal species from which they are obtained; their purity, concentration, and solubility; and the time of onset and duration of their biologic action. An oral hypoglycemic agent is not a form of insulin therapy.

Combination therapy may improve health outcomes in adolescents with type 1 diabetes

A clinical trial involving adolescents with type 1 diabetes (T1D) has found a combination therapy may reduce chronic kidney disease and improve health outcomes.

17 Jun 2025

What 300 grams of ultra-processed food a day does to your diabetes risk

A dose-response meta-analysis of 12 cohort studies finds that higher intake of ultra-processed foods (UPFs) is linked to a significantly increased risk of type 2 diabetes (T2D). The association remains even after adjusting for BMI, diet quality, and energy intake, with a steeper risk increase above 300 g/day.

17 Jun 2025

Muscle ultrasound shows promise for early insulin resistance detection

A simple ultrasound of a patient's thigh or shoulder muscle may detect insulin resistance before it progresses to type 2 diabetes or even prediabetes.

17 Jun 2025

Could a diabetes drug be the key to stopping Alzheimer’s?

Investigating tirzepatide's role in Alzheimer's reveals its potential to improve brain function and reduce inflammation, linking diabetes and neurodegeneration.

17 Jun 2025

Mapping genetic activity offers new clues for personalized cancer treatment

City of Hope®, one of the largest and most advanced cancer research and treatment organizations in the U.S. with its National Medical Center named top 5 in the nation for cancer by U.S. News & World Report, co-led the first study to demonstrate that characterizing genetic material near chromosomes forecasts how mutated, cancer-causing genes reengineer DNA and alter the tumor microenvironment.

13 Jun 2025

Short peptides show promise in blocking breast cancer metastasis

A surgeon can excise breast cancer from the body, but even the most skilled scalpel may not be able to remove every cell - especially when the cells have spread from the original disease site elsewhere in the body.

13 Jun 2025

Meal and sleep timing play key roles in diabetes prevention

High-resolution digital tracking reveals how daily habits, meal timing, sleep, and physical activity shape metabolic risk for type 2 diabetes. Meal timing, sleep patterns, and activity windows each play distinct roles in insulin resistance and glucose control.

12 Jun 2025

APOE gene variants influence metabolic patterns linked to aging and Alzheimer’s risk

A new research paper was published in Aging (Aging-US) Volume 17, Issue 5, on May 3, 2025, titled "APOE genotype and biological age impact inter-omic associations related to bioenergetics."

12 Jun 2025

Waist-to-height ratio found to predict liver damage better than BMI

Excess fat mass estimated by waist circumference-to-height ratio predicts the risk of liver damage better than body mass index (BMI) estimated obesity, a new study shows.

11 Jun 2025

Tufts researchers design new generation of weight loss medications

Weight loss drugs like Ozempic and Wegovy are used by over 15 million adults in the U.S., or 4.5% of the population. Despite their effectiveness, they have drawbacks.

11 Jun 2025

Chromium-rich fiber supplement keeps you fuller and reduces insulin spikes

A single dose of a chromium-enriched glucomannan-fructo-oligosaccharide fiber complex significantly reduced postprandial insulin and increased fullness in healthy adults, without affecting blood glucose. These findings highlight the potential of this functional fiber blend to support appetite control and metabolic health.

10 Jun 2025

New guideline puts lifestyle interventions at the forefront of type 2 diabetes and prediabetes care

The American College of Lifestyle Medicine (ACLM) has published the first clinical practice guideline to put lifestyle interventions at the forefront of type 2 diabetes and prediabetes care.

10 Jun 2025

Digital twin technology improves diabetes control with artificial pancreas

New technology that allows a University of Virginia-developed artificial pancreas system to adapt to users' changing bodies – and lets users test changes to how the system operates – improved control of their type 1 diabetes, a study has found.

10 Jun 2025

What happens to your body and mind during a five-day water fast?

A five-day water-only fast led to significant weight, fat, and lean muscle loss in middle-aged women, along with improved mood and marked changes in metabolic and inflammatory markers. The study also found that psychological traits like emotional intelligence and impulsivity influenced the amount of fat and muscle lost during fasting.

9 Jun 2025

Small weight loss leads to big gains in heart health

Even without weight loss, healthy lifestyle changes enhance heart health. This study highlights the importance of habits for cardiometabolic improvement.

9 Jun 2025

Healthy diet improves metabolism even without weight loss

Nearly one-third of people who adopted and adhered to a healthy diet did not lose any weight, but still reaped many health benefits, according to a new study led by researchers at Harvard T.H. Chan School of Public Health and Ben Gurion University, Israel.

6 Jun 2025