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Implantable device boosts immune cells to fight cancer effectively

Immunotherapy has transformed cancer treatment by harnessing the body's own immune system to fight disease.

17 Mar 2026

Blocking fructose metabolism may improve brain tumor immunotherapy response

Northwestern Medicine scientists have discovered that specialized immune cells within the glioblastoma tumor metabolize fructose to suppress immune responses and promote tumor growth, reports a study published on March 17 in the Proceedings of the National Academy of Sciences.

17 Mar 2026

New CAR-T cell therapy shows promise for treating osteosarcoma

Finding an effective treatment for osteosarcoma, the most common type of bone cancer in children and young adults, has puzzled medical researchers for 40 years.

17 Mar 2026

Expert consensus validates UDFF for noninvasive fatty liver assessment

As the global burden of obesity, type 2 diabetes, and metabolic syndrome continues to rise, fatty liver disease has become one of the most prevalent chronic liver conditions worldwide. Its progressive forms, including metabolic dysfunction‐associated steatohepatitis (MASH), cirrhosis, and hepatocellular carcinoma, now represent a major public health challenge.

17 Mar 2026

New insight into origins of rare liver tumors in children

Liver cancer in children is rare, but when it occurs the two main types are hepatoblastoma (HB) and hepatocellular carcinoma (HCC).

16 Mar 2026

New CAR-NKT cell therapy shows promise against aggressive endometrial cancer

Endometrial cancer is the most common gynecologic cancer in the United States and is one of the few cancers in which survival rates have steadily declined over the last few decades.

16 Mar 2026

Protein MIIP suppresses colorectal cancer by regulating immune cell signaling

Colorectal cancer remains one of the leading causes of cancer-related mortality worldwide, largely due to metastasis and limited responses to immunotherapy in most patients.

16 Mar 2026

Researchers develop targeted delivery system for poorly soluble cancer drugs

Recent advances in drug discovery research have led to the development of numerous drug candidate compounds with high therapeutic efficacy.

16 Mar 2026

Clinical trial tests a newer, targeted therapy for IDH mutant astrocytoma

A new clinical trial led by the Alliance for Clinical Trials in Oncology will investigate if a combination of drug therapies after radiation therapy improves outcomes for people with newly-diagnosed, grade 3 IDH-mutant astrocytoma, a type of brain cancer.

16 Mar 2026

New insights highlight multifaceted roles of CD4+ T cells in tumor immunity

For decades, cancer immunotherapy has focused primarily on CD8+ cytotoxic T lymphocytes as the main executors of tumor cell killing.

13 Mar 2026

SonoPIN technology boosts intracellular delivery of large cancer drugs

Engineers at Duke University have demonstrated a technique that uses microbubbles and ultrasound to help relatively large cancer drugs enter tumor cells and cause them to self-destruct.

13 Mar 2026

New method creates longer lasting CAR T cells for cancer therapy

A research team led by Albert Einstein College of Medicine scientists has developed a new strategy to engineer immune cells that dramatically prolongs their effectiveness after being infused into patients to fight cancer and HIV, addressing a major limitation of current treatments.

13 Mar 2026

Combined CDK4/6 and EGFR inhibition improves pancreatic cancer therapy

Clinically available KRAS inhibitors mainly target G12C, which is rare in PDAC and often acquires resistance. Oncogenic KRAS inactivates RB1 via CDK4/6, while RB1 mutation is rare.

13 Mar 2026

Scientists win awards for the discovery of genomic imprinting and tumor’s power grid

For their discovery of genomic imprinting, developmental biologists Davor Solter and Azim Surani will receive the 2026 Paul Ehrlich and Ludwig Darmstaedter Prize, endowed with €120,000, on March 14 at Frankfurt’s Paulskirche.

13 Mar 2026

Experimental therapy eliminates pancreatic precancerous cells in mice study

A new preclinical study in mice shows that precancerous cells in the pancreas can be eliminated before they have the chance to become tumors.

12 Mar 2026

Scientists uncover unexpected cancer target on tumor cell surfaces

For five decades, scientists have known about a notorious cancer-causing enzyme called SRC. But they always assumed it only appeared on the inside of cells, where it sent signals that fueled tumor growth and stayed hidden from the immune system.

12 Mar 2026

Topical cream activates immune response to suppress skin cancer growth

A topical cream activated the skin's immune defenses and suppressed tumor growth in two preclinical models of cutaneous squamous cell carcinoma (cSCC), one of the most common cancers in the world, according to a study published today in the Journal of Clinical Investigation.

12 Mar 2026

Can eating almonds reduce inflammation in obesity?

Adding almonds to the diet of adults with obesity enhances inflammatory cytokine profiles and diet quality, highlighting a simple anti-inflammatory strategy.

12 Mar 2026

Decoding the neighborhood dynamics of childhood brain cancer

New research published in Nature finds that tumor cells within supratentorial ependymomas (SE) – an aggressive childhood brain cancer – cluster into distinct tumor cell populations. Much like a neighborhood in your hometown, each cell subtype within these "communities" has a specific (and previously unappreciated) role to play.

12 Mar 2026

New protein target for safer lung cancer therapy

Researchers at the University of Gothenburg have identified a protein linked to an increased risk of metastasis and recurrence in lung cancer. The findings are presented in a study that paves the way for new precision medicine approaches, particularly for older patients.

12 Mar 2026