Lymph Node News and Research

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Lymph is clear or white fluid that travels through vessels, moves within tissues and work to keep all the parts of the body clean. After passing through the channels of the lymphatic system they drain into the lymph nodes. The lymph nodes act as filters along the lymphatic system. These nodes trap germs like bacteria, viruses, toxins as well as cancer cells and ensure that these are removed from the body.

New 'dual-mode' tracer agent enhances precision in prostate cancer procedures

A preclinical evaluation of a new 'dual-mode' tracer agent shows promise in not only helping surgeons image and plan prostate cancer procedures, but also provide them with much more consistent and targeted guidance during surgery.

21 Aug 2025

Vaccines trigger immediate changes in lymph node tissue landscape

Vaccines trigger a notably rapid response in the stromal cells of draining lymph nodes within the first hours after administration.

18 Aug 2025

2025 Chikungunya outbreak: A global health challenge

Chikungunya virus (CHIKV) is a mosquito-borne alphavirus causing fever, severe joint pain, rash, and muscle aches, mainly transmitted by Aedes mosquitoes. As of 2025,

From Sino Biological Inc. 18 Aug 2025

Engineered CD40 antibody shrinks tumors and induces remission

Over the past 20 years, a class of cancer drugs called CD40 agonist antibodies have shown great promise-and induced great disappointment.

14 Aug 2025

Novel vaccine shows promise against KRAS-driven pancreatic and colorectal cancers

A novel cancer vaccine that stimulates the immune system to target one of the most common cancer-driving mutations has shown encouraging early results in patients with pancreatic and colorectal cancer, two of the most difficult-to-treat malignancies, according to a study led in part by investigators at the UCLA Health Jonsson Comprehensive Cancer Center.

12 Aug 2025

Early-onset pancreatic cancer patients benefit more from neoadjuvant chemotherapy and surgery

The incidence of early-onset pancreatic cancer (EOPC) is rising, yet optimal treatment strategies remain unclear.

7 Aug 2025

Starfish compound overcomes drug resistance in prostate cancer models

Researchers identified that triterpene glycosides from the starfish Solaster pacificus can kill drug-resistant prostate cancer cells in vitro by bypassing common resistance pathways. CuC1 showed synergy with existing chemotherapies, though with only moderate selectivity for cancer cells.

5 Aug 2025

AI algorithm identifies one-third of missed breast cancers in DBT screenings

An AI algorithm for breast cancer screening has potential to enhance the performance of digital breast tomosynthesis (DBT), reducing interval cancers by up to one-third, according to a study published today in Radiology, a journal of the Radiological Society of North America.

29 Jul 2025

Scientists identify key role of T-bet in flu memory B cells

At the surface, the immune response to a flu virus is simple. Some cells recognize the pathogen and send a signal to the immune system, and immune cells produce a potentially lifesaving antibody against the virus. Antigen in, antibody out.

11 Jul 2025

New dual-adjuvant vaccine strategy offers hope in the fight against HIV

In the quest to develop an effective HIV vaccine, scientists from Scripps Research have made a significant leap forward. They found that a two-part delivery strategy can train the immune system to produce a stronger response to HIV, offering new hope in the fight against one of the world's most elusive viruses.

19 Jun 2025

Deep B cell depletion offers new hope for rheumatologic and musculoskeletal diseases

CD19-CAR T-cell treatment is a novel option of deep B cell depletion with promising results across different rheumatologic and musculoskeletal diseases (RMD).

15 Jun 2025

Advancing precision oncology in intrahepatic cholangiocarcinoma

ICCA accounts for 10–15% of primary liver cancers and is notorious for late-stage diagnosis and resistance to chemotherapy and radiotherapy.

13 Jun 2025

Short peptides show promise in blocking breast cancer metastasis

A surgeon can excise breast cancer from the body, but even the most skilled scalpel may not be able to remove every cell - especially when the cells have spread from the original disease site elsewhere in the body.

13 Jun 2025

Engineered lymph node model advances human immune system research

Scientists with the Fralin Biomedical Research Institute at VTC have created an engineered model of the supportive tissue found within a lymph node to study human health.

12 Jun 2025

Meta analysis highlights prognostic role of circPVT1 in solid tumors

circPVT1 has emerged as a key regulator in disease progression and clinical outcomes. However, its prognostic relevance and association with clinicopathological parameters in solid malignancies remain to be fully elucidated.

22 May 2025

Nasal vaccine boosters can trigger strong immune defenses in the respiratory tract, study finds

Most vaccines — and boosters — are injected directly into muscle tissue, usually in the upper arm, to kickstart the body's immune system in the fight against disease.

13 May 2025

Study identifies key enzyme linked to metastasis in head and neck cancer

A recent study published in Engineering has shed new light on the mechanisms underlying the metastasis of head and neck squamous cell carcinoma (HNSCC).

8 May 2025

Immunotherapy replaces surgery for early-stage dMMR cancers in landmark study

Neoadjuvant PD-1 blockade with dostarlimab achieved high rates of organ preservation in patients with early-stage mismatch repair-deficient (dMMR) solid tumors across multiple types. Most patients avoided surgery with durable disease control, reshaping potential cancer treatment pathways.

28 Apr 2025

New subtype of Castleman disease identified to improve diagnosis and treatment

A newly identified subtype of Castleman disease will help diagnose and properly treat thousands of patients who have been caught between existing classification systems, marking the first major discovery of its kind in 45 years.

22 Apr 2025