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Ribonucleic acid (RNA) is a biologically important type of molecule that consists of a long chain of nucleotide units. Each nucleotide consists of a nitrogenous base, a ribose sugar, and a phosphate.

A metabolic intermediate in the uronic acid pathway impairs lung cancer metastasis

In a study published online in Nature on June 26, research teams led by Dr. YANG Weiwei at the Institute of Biochemistry and Cell Biology of the Chinese Academy of Sciences and Dr. LI Guohui from the Dalian Institute of Chemical Physics of CAS reported a new function of uridine diphosphate glucose (UDP-glucose), a metabolic intermediate in the uronic acid pathway: It impairs lung cancer metastasis by accelerating SNAI1 mRNA decay.

27 Jun 2019

Using Light Scattering to Characterize Protein-Nucleic Acid Interactions

Harnessing the interactions between DNA, RNA, and proteins holds much promise for detecting biomarkers, diagnosing disease, and improving cancer-targeting therapeutics. Quantifying these interactions is essential for understanding and controlling their biomolecular mechanisms.

From Waters | Wyatt Technology 26 Jun 2019

Researchers develop new technique to image cell populations and genetic contents

Researchers have come up with a new way to image cell populations and their genetic contents. Their study, appearing June 20 in the journal Cell, describes how a technique called DNA microscopy helps illuminate the spatial organization of genetic material within cells and tissues without specialized, expensive optical equipment.

24 Jun 2019

Elite group of immune cells plays key role in fighting tumors

Immunotherapies hold promise as a way to prompt a patient's own immune system to fight cancer cells. Yet immunotherapies only work in about 30 percent of patients - and they can cause dangerous side effects.

24 Jun 2019

Introduction of very small RNA molecule promotes heart cell regeneration, study shows

By adulthood, the heart is no longer able to replenish injured or diseased cells. As a result, heart disease or an event like a heart attack can be disastrous, leading to massive cell death and permanent declines in function.

23 Jun 2019

New DNA Microscopy Technique Offers Novel Insight into Genomic Information in Cells

Scientists are now able to see inside cells to a genomic level with a newly invented imaging technique called DNA microscopy. Using DNA “bar codes”, DNA microscopy allows scientists to locate a molecule’s position in a sample without using any kind of optics, meaning genomic information can be collected in large amounts.

21 Jun 2019

Scientists develop a stable platform to reprogram scar tissue into healthy heart cells

Every year 790,000 Americans suffer a heart attack, which leaves damaged scar tissue on the heart and limits its ability to beat efficiently.

21 Jun 2019

Researchers identify genes linked with survival in children with biliary atresia

Scientists at Cincinnati Children's Hospital Medical Center have identified an expression pattern of 14 genes at the time of diagnosis that predicts two year, transplant-free survival in children with biliary atresia – the most common diagnosis leading to liver transplants in children.

19 Jun 2019

Highlights and key takeaways from the 2019 Boston Bacterial Meeting (BBM)

Missed out on the 2019 Boston Bacterial Meeting (BBM)? Read our round-up of the key takeaways, areas of discussion, speakers and more.

19 Jun 2019

Researchers uncover new mechanism by which cells communicate in inflammatory processes

A research group from MedUni Vienna and CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences has discovered a new mechanism by which cells communicate in inflammatory processes.

14 Jun 2019

IDT unveils latest additions to NGS portfolio at European Human Genetics Conference

As part of its ongoing mission to advocate for researchers in the genomics age, Integrated DNA Technologies will unveil the latest additions to its NGS catalog to the European market at the European Human Genetics Conference in Gothenburg, Sweden on 15–18 June, 2019.

From Integrated DNA Technologies 13 Jun 2019

New technology harnesses bacterial jumping genes for precise DNA integration

A new discovery by researchers at Columbia University Vagelos College of Physicians and Surgeons could fix one of the major shortcomings of current gene-editing tools, including CRISPR, and offer a powerful new approach for genetic engineering and gene therapy.

13 Jun 2019

Researchers reveal underlying mechanism that protects genetic transcripts in cells

The cell contains transcripts of the genetic material, which migrate from the cell nucleus to another part of the cell. This movement protects the genetic transcripts from the recruitment of "spliceosomes".

13 Jun 2019

Identifying colorectal cancer subtypes in patients could help provide better care

Colorectal cancer is the second leading cause of cancer death in the U.S., expected to cause about 51,000 deaths in 2019. But until now, it was unclear which drugs were most effective for which patients.

12 Jun 2019

Scientists discover weakness in common cold virus

Scientists have discovered a weakness on the surface of the viruses that cause a multitude of illnesses.

12 Jun 2019

Identifying subtype of colorectal cancer may help oncologists determine most effective treatment

12 Jun 2019

New research identifies cellular adaptive mechanisms during hypoxic conditions

Circadian rhythms are 24 hour cycles that are guided by exposure to alternating periods of day and night. These cycles affect biological activities in a variety of living organisms which are attuned to the circadian clock.

12 Jun 2019

Plant-derived siRNAs could bring a 'green revolution' in RNAi tools and therapeutics

"Green revolution" in the early 1950s, the extensive cultivation of Dwarf Rice solves the food problem in developing countries. At present, chronic infection with hepatitis B virus (HBV) has been a major public health problem.

11 Jun 2019

Researchers compare American, Pacific and Southeast Asian subtypes of Zika virus

Over recent years, Zika virus has spread eastward from Africa and Asia, leading to an epidemic in the Americas. Now, researchers comparing American, Pacific and Southeast Asian subtypes of the virus in PLOS Neglected Tropical Diseases have concluded that the American-subtype strain has the highest ability to grow both in vitro and in vivo.

From PLOS ONE 10 Jun 2019

Bruker launches timsTOF fleX with ESI/MALDI capability for SpatialOMx at ASMS 2019

Bruker Daltonics has launched a novel timsTOF fleX mass spectrometer which combines ESI/MALDI capability for SpatialOMx on a single instrument.

From Bruker Daltonics 10 Jun 2019

RNA News and Research

Further Reading

A metabolic intermediate in the uronic acid pathway impairs lung cancer metastasis

Using Light Scattering to Characterize Protein-Nucleic Acid Interactions

Researchers develop new technique to image cell populations and genetic contents

Elite group of immune cells plays key role in fighting tumors

Introduction of very small RNA molecule promotes heart cell regeneration, study shows

New DNA Microscopy Technique Offers Novel Insight into Genomic Information in Cells

Scientists develop a stable platform to reprogram scar tissue into healthy heart cells

Researchers identify genes linked with survival in children with biliary atresia

Highlights and key takeaways from the 2019 Boston Bacterial Meeting (BBM)

Researchers uncover new mechanism by which cells communicate in inflammatory processes

IDT unveils latest additions to NGS portfolio at European Human Genetics Conference

New technology harnesses bacterial jumping genes for precise DNA integration

Researchers reveal underlying mechanism that protects genetic transcripts in cells

Identifying colorectal cancer subtypes in patients could help provide better care

Scientists discover weakness in common cold virus

Identifying subtype of colorectal cancer may help oncologists determine most effective treatment

New research identifies cellular adaptive mechanisms during hypoxic conditions

Plant-derived siRNAs could bring a 'green revolution' in RNAi tools and therapeutics

Researchers compare American, Pacific and Southeast Asian subtypes of Zika virus

Bruker launches timsTOF fleX with ESI/MALDI capability for SpatialOMx at ASMS 2019

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