Kidney News and Research

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Stem cells and organoids offer a new understanding of APOL1 kidney disease

Chronic kidney disease (CKD) affects more than 700 million people worldwide and is caused by genetic and environmental factors, as well as existing medical conditions. Known genetic risk factors for CKD include mutations in a gene called APOL1.

3 Oct 2025

Restoring delta cell function may prevent dangerous hypoglycemic events in diabetes

A new study by the University of California, Davis, shows how cells work together to avoid a sudden drop in blood sugar. Understanding these feedback loops could improve the lives of people with diabetes and help them avoid dangerous hypoglycemia.

3 Oct 2025

Inactive blood marker SDMA emerges as potential predictor of cardiovascular risk in CKD

When University of Texas at Arlington researcher Paul J. Fadel and his colleagues launched a study on vascular health in people with chronic kidney disease, they expected to better understand a long-standing belief.

3 Oct 2025

Study finds limited value of CGM data for non-diabetic individuals

Continuous glucose monitors (CGMs) are wearable technologies that track blood sugar in real time and help patients with type 2 diabetes improve blood sugar control.

2 Oct 2025

Shift workers face higher risk of developing kidney stones

A study evaluating how various shift work patterns contribute to kidney stone risk has revealed that shift workers have a 15% higher risk of developing kidney stones, especially younger workers and those with low levels of manual labor.

2 Oct 2025

Prediabetes can go into remission without weight loss

Research shows up to 22% of prediabetic individuals achieve remission without weight loss, emphasizing metabolic health over weight loss in diabetes prevention.

2 Oct 2025

Genetic risk scores fail to predict survival after diagnosis

Research indicates that disease susceptibility genetics poorly predict survival, while longevity PGSs offer stronger associations with post-diagnosis mortality.

2 Oct 2025

Study shows prediabetes remission does not always require weight loss

Remission of prediabetes can occur even without weight loss, protecting against type 2 diabetes in up to 22% of individuals. Metabolic improvements, healthier fat distribution, and enhanced β-cell function, not body weight change, drive this benefit.

30 Sep 2025

Inflammation at the heart’s core: What clinicians and families can do now

Chronic low-grade inflammation is a key driver of cardiovascular disease, even when cholesterol is controlled. The ACC’s 2025 Scientific Statement highlights hsCRP as a routine risk marker and outlines lifestyle and pharmacologic anti-inflammatory strategies for prevention and treatment.

30 Sep 2025

Undiagnosed G6PD deficiency can lead to delayed diabetes diagnosis for Black and Asian men

A common but often undiagnosed genetic condition may be causing delays in type 2 diabetes diagnoses and increasing the risk of serious complications for thousands of Black and South Asian men in the UK - and potentially millions worldwide.

30 Sep 2025

Myo-inositol fails to lower pregnancy risks in women with PCOS

Myo-inositol supplementation shows no significant benefits in preventing pregnancy complications for women with PCOS, according to a recent large-scale study.

30 Sep 2025

Yale researchers develop new test for early leptospirosis detection

In a new study, Yale School of Medicine (YSM) researchers unveiled a novel diagnostic method for detecting leptospiral virulence-modifying (VM) proteins in the blood and urine of hamsters, an advance that could pave the way for early diagnosis of the tropical disease leptospirosis in humans and improved treatment options.

29 Sep 2025

New mRNA vaccine stops allergens from causing life-threatening inflammation in mice

A new mRNA vaccine stopped allergens from causing dangerous immune reactions and life-threatening inflammation in mice, according to researchers from the Perelman School of Medicine at the University of Pennsylvania and Cincinnati Children's.

29 Sep 2025

Modifiable risk factors could double global kidney cancer cases by 2050

Modifiable risk factors such as obesity, smoking, lack of exercise, diabetes and hypertension are projected to be one of the main drivers of a steep rise in kidney cancer cases, doubling the amount worldwide over the next 25 years, according to a new study recently published in European Urology.

26 Sep 2025

Big loopholes in hospital charity care programs mean patients still get stuck with the tab

Quinn Cochran-Zipp went to the emergency room three times with severe abdominal pain before doctors figured out she had early-stage cancer in the germ cells of her right ovary.

25 Sep 2025

Stem cell treatment could help millions of people with end-stage kidney disease

More than 4 million people worldwide have end-stage kidney disease that requires hemodialysis, a treatment in which a machine filters waste from the blood.

24 Sep 2025

Blood and brain biomarkers transform how doctors confirm Alzheimer’s disease

A new Lancet review proposes a three-wave diagnostic pathway that combines clinical expertise with blood, CSF, and PET biomarkers. This approach aims to deliver earlier, more accurate, and more equitable Alzheimer’s disease diagnosis worldwide.

24 Sep 2025

Researchers explore blueberries as a tool to support microbiota in early life

Researchers tested blueberry powder as one of the first complementary foods in human milk-fed infants. The trial found exploratory evidence that blueberries may support healthier gut microbiota development during early life.

24 Sep 2025

How food choices and cooking methods drive brain inflammation and disease

Researchers reviewing evidence in NeuroSci show how dietary AGEs and their interaction with RAGE drive oxidative stress, inflammation, and neurodegeneration. They highlight how cooking methods and diet choices could lower AGE burden and protect brain health, while calling for rigorous clinical trials.

24 Sep 2025

Scientists outline how future therapies could change type 1 diabetes care

Researchers writing in The Lancet review breakthroughs in type 1 diabetes treatment, from immunotherapies that delay onset to stem-cell β-cell replacement and automated insulin delivery. They stress that equitable access, validated surrogate endpoints, and scalable technologies are crucial for lasting impact.

24 Sep 2025