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Statin use alone or with metformin may increase survival in high-risk prostate cancer patients

Among high-risk prostate cancer patients - those with high PSA and Gleason scores of 8 or more - many will develop a difficult-to-treat disease.

10 Feb 2020

Clinical trial of two investigational drugs for rare, inherited Alzheimer's yields disappointing results

An international clinical trial evaluating whether two investigational drugs can slow memory loss and cognitive decline in people in the early stages of a rare, inherited form of Alzheimer's disease has yielded disappointing results, an initial analysis of the data has shown.

10 Feb 2020

Novel innate immunity factor inhibits HIV infection by targeting lipid rafts, study finds

The human protein apolipoprotein A-I binding protein inhibits HIV replication by targeting lipid rafts and reducing virus-cell fusion, according to a new study published in the premier American Society for Microbiology journal mBio by researchers from the George Washington University.

10 Feb 2020

Researchers simulate leaky gut conditions using 3D models of human intestines

Once a vague scapegoat for a variety of ills, increasing evidence suggests a condition known as "leaky gut" -- in which microbes and other molecules seep out of the intestines -- may be more common, and more harmful, than previously thought.

10 Feb 2020

New treatment effective at reversing the manifestations of thyroid eye disease

Patients with thyroid eye disease who used the minimally invasive insulin-like growth factor I blocking antibody, teprotumumab, experienced improvement in their symptoms, appearance and quality of life, according to a study recently published in the New England Journal of Medicine.

10 Feb 2020

Youth with HIV have lower rates of viral suppression than adults

Despite similar rates of enrollment into medical care, youth with HIV have much lower rates of viral suppression--reducing HIV to undetectable levels--compared to adults, according to an analysis funded by the National Institutes of Health.

10 Feb 2020

Common drug could mitigate risk of 'a broken heart' during bereavement

The increased risk of heart attack or "a broken heart" in early bereavement could be reduced by using common medication in a novel way, according to a world-first study led by the University of Sydney and funded by Heart Research Australia.

10 Feb 2020

Outcomes-based drug reimbursement may be on the horizon, report says

How can pharma and life sciences be prepared and agile enough to respond to future challenges if it has not thought about the current trends and emerging challenges?

10 Feb 2020

Bayer and Meiogenix join forces to advance agricultural research and development

Bayer and Meiogenix, a biotech company focused on next-generation breeding technologies, announced today a collaboration to advance agricultural research and development by accelerating the development of Meiogenix's proprietary technologies related to plant breeding and genome editing applications.

From Bayer AG 10 Feb 2020

Higher maternal blood pressure linked to placental gene modifications

Higher maternal blood pressure in pregnancy is associated with chemical modifications to placental genes, according to a study by researchers from the Eunice Kennedy Shriver National Institute of Child Health and Human Development, part of the National Institutes of Health.

10 Feb 2020

Protein Data Bank archive releases new coronavirus protease structure

The Protein Data Bank archive, which contains more than 160,000 3D structures for proteins, DNA, and RNA, this month released a new Coronavirus protease structure following the recent coronavirus outbreak, an ongoing viral epidemic primarily affecting mainland China that now threatens to spread to populations in other parts of the world.

10 Feb 2020

How lifesaving organs for transplant go missing in transit

When a human heart was left behind by mistake on a Southwest Airlines plane in 2018, transplant officials downplayed the incident. They emphasized that the organ was used for valves and tissues, not to save the life of a waiting patient, so the delay was inconsequential.

10 Feb 2020

Single dose of HPV vaccine is effective for preventing preinvasive cervical disease

New research indicates that a single dose of the human papillomavirus vaccine is as effective as multiple doses for preventing preinvasive cervical disease, which can later develop into cervical cancer.

10 Feb 2020

Study uncovers new avenue for melanoma diagnosis and therapies

A new way to spot melanoma cells circulating in the blood has the potential to significantly improve the monitoring of cancer patients and guide future treatment.

10 Feb 2020

Research reveals novel way to treat cancers using CAR T cell therapy

Too many patients with cancers like multiple myeloma relapse after treatment. This grim reality motivated researchers at Huntsman Cancer Institute at the University of Utah to try to improve the depth and durability of treatment response in multiple myeloma through a new cancer cell targeting mechanism.

10 Feb 2020

UK facing a major coronavirus outbreak, experts warn

The novel coronavirus (2019-nCoV or Wuhan coronavirus) is spreading like wildfire across the globe and health officials are racing to contain the virus. Experts in the United Kingdom warn that the country is facing a major coronavirus outbreak in the coming weeks as the number of confirmed cases rises to four, as more than 25 countries have reported increasing case toll.

9 Feb 2020

Chemical in veggies help heal fatty liver

A new study shows that a compound naturally occurring in a variety of commonly used vegetables as well as being produced by gut microbes is very useful in melting fat away from a fatty liver.

9 Feb 2020

High bacterial levels in half of lupus skin rashes

A new study published in the Journal of Investigative Dermatology reports that half the skin lesions present in patients with lupus show the presence of viable staph bacteria. This makes them more susceptible to skin infections and also increases the risk that the infection will spread to others.

9 Feb 2020

Growing eggs and sperm to treat infertility

Scientists at the University of California, Los Angeles, have reported, in the journal Cell Reports, the mechanism of how the very early precursor or stem cells which eventually give rise to the germ cells, eggs and sperm, are formed over the course of development. This could help create eggs and sperms under laboratory conditions to help infertile people who don’t have sperms, or eggs, for instance.

9 Feb 2020

Discovery of potential cause of age-related macular degeneration

Age related macular degeneration or AMD leads to loss of vision in around 1.5 million people in the United Kingdom and millions of others around the world. In a new study researchers have discovered a new protein that could explain the causation and thus provide clues to its early diagnosis and effective treatment. The study was published in the latest issue of the journal Nature Communications.

9 Feb 2020