in vivo News and Research

RSS

Scientists advance type 1 diabetes treatment with cutting-edge stem cell and gene editing technologies

Researchers review significant advancements and ongoing challenges in cell replacement therapies for type 1 diabetes, highlighting innovative approaches in stem cell-derived islets and immune protection strategies.

5 Sep 2024

Promising new strategy to combat fungal infections

A group of Brazilian researchers has found a potential target for novel therapeutic strategies to combat fungal infections – more specifically, those caused by Aspergillus fumigatus. An article reporting the discovery is published in the journal Communications Biology.

5 Sep 2024

Alirocumab reduces dangerous coronary plaque and stabilizes high-risk lesions

Intensive LDL-C lowering with alirocumab significantly reduces high-risk coronary plaque burden, transforming unstable plaques into more stable phenotypes. This lesion-level analysis underscores the enhanced efficacy compared to vessel-level approaches.

4 Sep 2024

Sapio Sciences advances the world's first AI-powered lab assistant

Sapio ELaiN couples AI and natural language processing to deliver the future interface for scientists and lab operations.

From Sapio Sciences 3 Sep 2024

Aptamer extends contract with Unilever to progress Optimer for deodorant development

Lab-test results of Optimer indicate good applicability in deodorant products.

From Aptamer Group 3 Sep 2024

Researchers develop stable compound for targeted alpha therapy in prostate cancer

Compounds containing astatine-211 (211At) can be used in targeted radiotherapies for prostate cancer, but deastatination in the body remains a significant hurdle.

3 Sep 2024

Dietary patterns like fasting and the Mediterranean diet unlock molecular secrets to healthy aging

Study reviews the molecular mechanisms by which caloric restriction, intermittent fasting, the Mediterranean diet, and the ketogenic diet promote healthy aging.

2 Sep 2024

Tirzepatide outperforms insulin in controlling diabetes and promoting weight loss in clinical trials

Tirzepatide, a once-weekly dual agonist, outperforms long-acting insulin in reducing HbA1c, body weight, and improving cardiovascular markers in Type 2 diabetes patients.

2 Sep 2024

NCCS study uses exosomes to overcome resistance to epidermal growth factor receptor inhibitors

In a new study, clinician-scientists and researchers from the National Cancer Centre Singapore (NCCS) have demonstrated the use of exosomes to successfully target squamous cell cancer tumours that are usually resistant to epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs). Their research is the first where exosomes have been applied to target TKI-resistant cancers in Singapore. The findings were published in the journal Developmental Cell last month.

2 Sep 2024

Fermented lingonberry juice shown to reduce inflammation and support gut health in IBD

Fermented lingonberry juice may help manage inflammatory bowel disease (IBD) by modulating both the oral and gut microbiomes, reducing inflammation, and promoting beneficial bacteria.

2 Sep 2024

Autophagy in HPCs modulates exosomal miRNAs to inhibit liver fibrosis

The study investigates the role of autophagy in hepatic progenitor cells (HPCs) and its potential to modulate exosomal microRNAs (miRNAs) to inhibit liver fibrosis in the context of schistosomiasis, a disease caused by parasitic flatworms that can lead to severe organ damage, particularly to the liver.

2 Sep 2024

Intranasal vaccine shows broad SARS-CoV-2 variant protection

Study demonstrates that a single-dose intranasal live-attenuated vaccine, CDO-7N-1, provides broad protection against SARS-CoV-2 and its variants by inducing potent immune responses, including neutralizing antibodies and T-cell activity, in animal models.

1 Sep 2024

New consensus on assessing carcinogenic risks of gene therapies

A new article in the peer-reviewed journal Human Gene Therapy describes the consensus reached by invited experts who participated in a meeting to evaluate the potential carcinogenicity of gene therapies.

30 Aug 2024

Sapio Sciences Successfully Completes SOC 2 Type 2 Examination and HIPAA/HITECH Attestation Examination

...

From Sapio Sciences 30 Aug 2024

$Regulatory T cells play a key role in fracture healing and tissue repair$

Regulatory T cells play a key role in fracture healing and tissue repair

The study uncovers a unique reparative function of regulatory T cells (Tregs) in the process of fracture healing, a discovery that adds a new dimension to our understanding of the immune response in tissue regeneration.

29 Aug 2024

Fibrin fuels thromboinflammation and brain damage in COVID-19

Researchers reveal fibrin's critical role in COVID-19 by driving thromboinflammation and neuropathology, and highlight a potential antibody therapy to mitigate these effects.

29 Aug 2024

Understanding the mechanisms of cardiac fibrosis

The article explores the role of the m6A reader YTHDF1 in cardiac fibrosis, a condition characterized by the excessive accumulation of extracellular matrix proteins, leading to the stiffening of the heart and impaired function. Cardiac fibrosis is a common pathological process in various cardiovascular diseases, including hypertension, myocardial infarction, and heart failure.

29 Aug 2024

in vivo News and Research

Scientists advance type 1 diabetes treatment with cutting-edge stem cell and gene editing technologies

Promising new strategy to combat fungal infections

Alirocumab reduces dangerous coronary plaque and stabilizes high-risk lesions

Sapio Sciences advances the world's first AI-powered lab assistant

Aptamer extends contract with Unilever to progress Optimer for deodorant development

Researchers develop stable compound for targeted alpha therapy in prostate cancer

Dietary patterns like fasting and the Mediterranean diet unlock molecular secrets to healthy aging

Tirzepatide outperforms insulin in controlling diabetes and promoting weight loss in clinical trials

NCCS study uses exosomes to overcome resistance to epidermal growth factor receptor inhibitors

Fermented lingonberry juice shown to reduce inflammation and support gut health in IBD

Autophagy in HPCs modulates exosomal miRNAs to inhibit liver fibrosis

Intranasal vaccine shows broad SARS-CoV-2 variant protection

New consensus on assessing carcinogenic risks of gene therapies

Sapio Sciences Successfully Completes SOC 2 Type 2 Examination and HIPAA/HITECH Attestation Examination

Regulatory T cells play a key role in fracture healing and tissue repair

Fibrin fuels thromboinflammation and brain damage in COVID-19

Understanding the mechanisms of cardiac fibrosis

New techniques in RNA engineering promise longer-lasting therapies

EPAM Joins Sapio Sciences Partner Program

Exploring OTUB1's influence on protein stability and atherosclerosis pathophysiology

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

Latest News