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New guidelines for identifying and treating high-risk IEC-HS patients

Chimeric antigen receptor T-cell (CAR-T) therapy has revolutionized the treatment of hematologic malignancies, offering durable responses for patients with otherwise refractory disease. However, its clinical success is accompanied by a spectrum of immune-related toxicities, which remain a major challenge in practice.

15 May 2026

New CRISPR breakthrough promises more affordable disease diagnostics

A team of engineers at the University of Florida has developed a new form of CRISPR technology that could make diagnostics and treatments safer, more precise, and more affordable, while opening the door to entirely new ways of controlling disease.

15 May 2026

Scientists call for innovative strategies to combat tuberculosis superspreaders

Superspreading became a familiar concept to many during the COVID-19 pandemic. Prior studies examining infectious disease epidemics, including those on COVID-19, have found that some individuals are much more likely to transmit infections to other people. Superspreading, when one person with an infection passes it to an unusually large number of other people, is a key feature of tuberculosis (TB) epidemiology.

15 May 2026

New FUSILLI tool improves gene fusion detection in pediatric leukemia

Researchers have introduced a novel diagnostics method that can more sensitively detect gene fusions in B-cell acute lymphoblastic leukemia (B-ALL), the most common type of pediatric cancer, compared to other publicly available fusion detection algorithms.

15 May 2026

Retinal stimulation via contact lenses effective as antidepressants in mice

Materials scientists have designed brain-stimulating contact lenses that are as effective as Prozac at treating depression in mice. The soft, transparent contact lenses have in-built electrodes that deliver mild electrical signals to the brain via the retina to stimulate specific brain regions associated with depression.

14 May 2026

Thyroid hormone profiles provide critical prognostic clues for patients facing liver failure

Early and accurate prognostic assessment is crucial to prevent disease progression in liver failure. Thyroid hormones (THs), particularly triiodothyronine (T3), are key metabolic regulators and play an important role in liver regeneration. Liver failure is frequently complicated by non‑thyroidal illness syndrome (NTIS), characterized by low T3 with normal or slightly elevated TSH and T4.

14 May 2026

Scientists identify methylphenidate as an effective tool for combating chronic cancer-related fatigue

A new meta-analysis in the May 2026 issue of JNCCN-Journal of the National Comprehensive Cancer Network provides updated evidence that methylphenidate-type psychostimulants-a class of medication that increases dopamine and norepinephrine availability in the brain-can provide meaningful relief for cancer-related fatigue.

14 May 2026

Scientists develop a superior diagnostic tool to spot hidden gene fusions in pediatric cancer

Researchers have introduced a novel diagnostic method that can more sensitively detect gene fusions in B-cell acute lymphoblastic leukemia (B-ALL), the most common type of pediatric cancer, compared to other publicly available fusion detection algorithms.

14 May 2026

New imaging technique maps 38000 liver cells to solve fibrosis

The liver is often called a "silent organ," as it can sustain significant damage without obvious symptoms. But when injury is prolonged, whether from alcohol, poor diet, or chronic hepatitis virus infection, it triggers fibrosis: a progressive hardening and scarring of liver tissue.

14 May 2026

Turning the flu virus into a powerful tool to fight cancer

A recent Views & Comments article published in Engineering highlights advances in repurposing influenza viruses as flexible therapeutic platforms for infectious diseases and cancer, driven by progress in reverse genetics and viral vector engineering.

14 May 2026

Four OICR-funded studies explore transformative approaches in cancer care

Four new research studies funded by the Ontario Institute for Cancer Research (OICR) will deliver cutting-edge innovations by maximizing the impact of existing research and making the most out of patient contributions.

13 May 2026

Sequential TACE after SBRT improves outcomes in recurrent hepatocellular carcinoma

Comparative data on sequential transarterial chemoembolization (TACE) after stereotactic body radiation therapy (SBRT) in recurrent hepatocellular carcinoma (HCC) remain limited. This study aimed to evaluate the efficacy of this combination.

13 May 2026

Next-generation cancer therapy shows early promise as treatment candidate for glioblastoma

A next-generation cancer therapy being developed at McMaster University has shown early promise as a treatment candidate for glioblastoma, the most aggressive and most common type of primary brain cancer in adults.

13 May 2026

GLP-1 obesity drugs mainly reduce fat while preserving muscle mass

New research to be presented at the European Congress on Obesity (ECO2026) in Istanbul, Turkey (12–15 May) shows that following treatment with GLP-1 drugs for obesity, most weight loss is fat mass (80–85%) and relative muscle mass is preserved.

13 May 2026

Study reveals hidden struggles faced by unaccompanied child refugees

From relentless cycles of intrusive memories to loneliness and physical pain - a new study form the University of East Anglia reveals the struggles of refugees who entered the UK as unaccompanied minors.

13 May 2026

Medical imaging could improve precision diagnosis of aggressive head and neck tumors

Medical imaging routinely used in cancer care may hold far more biological information than previously thought.

13 May 2026

New gene editing approach improves survival in epileptic mice

In a world first, a research team at the University of Zurich has successfully treated mice carrying an inherited form of epilepsy.

13 May 2026

Once-daily orforglipron helps preserve weight loss after semaglutide or tirzepatide

Oral orforglipron helped adults maintain clinically meaningful weight loss after prior injectable tirzepatide or semaglutide therapy. The phase 3b ATTAIN-MAINTAIN trial suggests switching to once-daily oral therapy may help reduce weight regain when injectable treatment is discontinued.

13 May 2026

Adding GLP-1 drugs to behavioral interventions silences food noise

New research presented at this year's European Congress on Obesity in Istanbul, Turkey, shows that use of obesity drugs alongside behavioral interventions leads to a larger drop in so called 'food noise' than in those using the behavioral therapy alone.

13 May 2026

Targeted ultrasound stimulation alters brain processing to reduce chronic pain

Using ultrasound to stimulate a specific part of the brain could offer a non-invasive therapy that benefits those experiencing chronic pain, a new study has suggested.

13 May 2026

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Therapy News and Research

New guidelines for identifying and treating high-risk IEC-HS patients

New CRISPR breakthrough promises more affordable disease diagnostics

Scientists call for innovative strategies to combat tuberculosis superspreaders

New FUSILLI tool improves gene fusion detection in pediatric leukemia

Retinal stimulation via contact lenses effective as antidepressants in mice

Thyroid hormone profiles provide critical prognostic clues for patients facing liver failure

Scientists identify methylphenidate as an effective tool for combating chronic cancer-related fatigue

Scientists develop a superior diagnostic tool to spot hidden gene fusions in pediatric cancer

New imaging technique maps 38000 liver cells to solve fibrosis

Turning the flu virus into a powerful tool to fight cancer

Four OICR-funded studies explore transformative approaches in cancer care

Sequential TACE after SBRT improves outcomes in recurrent hepatocellular carcinoma

Next-generation cancer therapy shows early promise as treatment candidate for glioblastoma

GLP-1 obesity drugs mainly reduce fat while preserving muscle mass

Study reveals hidden struggles faced by unaccompanied child refugees

Medical imaging could improve precision diagnosis of aggressive head and neck tumors

New gene editing approach improves survival in epileptic mice

Once-daily orforglipron helps preserve weight loss after semaglutide or tirzepatide

Adding GLP-1 drugs to behavioral interventions silences food noise

Targeted ultrasound stimulation alters brain processing to reduce chronic pain

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