Protein News and Research

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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

Ohio State study unlocks the long-standing mystery of RNA interference

While scientists have known for over two decades that all cells use a strategy called RNA interference to regulate gene expression, a new study is the first to describe how a specific protein manages the step-by-step process of assembling the molecular complex that performs the regulatory job.

26 May 2026

Estrogen decline alters brain cell matrix in older females

A largely overlooked space between cells in women's brains may hold the key to understanding memory loss tied to estrogen decline after menopause, reports a new preclinical Northwestern Medicine study.

26 May 2026

Study explains how environmental acidity destabilizes internal cellular traffic

A new scientific study led by the Universidad Carlos III de Madrid (UC3M) describes the mechano-chemical mechanism by which the acidity of the cellular environment destabilizes microtubules, the "avenues" that organize internal cellular traffic.

26 May 2026

Indian adapted Mediterranean diet targets inflammation in heart disease trial

The paper describes a single-center randomized controlled trial testing whether an Indian Adapted Mediterranean Diet can reduce dietary inflammation in adults with stable coronary artery disease or moderate-to-high cardiovascular risk. The protocol will assess changes in the Dietary Inflammatory Index, inflammatory biomarkers, cardiometabolic risk factors, body measurements, and metabolic hormones over six months.

25 May 2026

Roswell Park scientists present five key cancer studies at clinical meeting

The research findings of experts from Roswell Park Comprehensive Cancer Center will be featured during the American Society of Clinical Oncology (ASCO) annual meeting May 29 to June 2 at McCormick Place in Chicago.

25 May 2026

Novel RNA modification mechanism drives metabolic fatty liver disease progression

Nonalcoholic fatty liver disease (NAFLD) is a prevalent metabolic disorder with a complex pathogenesis. Although epitranscriptomic modifications such as N6-methyladenosine (m6A) have been implicated in NAFLD, the role of N1-methyladenosine (m1A) and its regulators is largely unexplored.

25 May 2026

New peptide triggers domino effect to suppress bladder cancer

Recently, a research team led by Professors Dahong Zhang and Qi Zhang from the Urology Department and the Institute of Urology at Zhejiang Provincial People's Hospital and the Translational Medicine Center discovered that a bladder tumor-targeting polyarginine peptide, R11, can directly bind to actin, destabilize the G-actin tetramer, and trigger the cascade breakdown of the actin-plectin-vimentin/ITGβ4 axis (referred to as the "cytoskeletal domino effect").

25 May 2026

New AI model detects hidden antibiotic resistance genes beyond standard databases

resLens uses genomic language models to detect antibiotic resistance genes from DNA sequences, performing especially well on long-read data and on some ARGs poorly represented in reference databases.

25 May 2026

Scientists reveal why common pancreatic precancer lesions rarely turn deadly

Spatial and single-cell analyses of human donor pancreata showed that PanIN epithelial cells gradually acquire cancer-like molecular features, while their surrounding stromal and immune environment remains closer to normal pancreatic tissue. The findings suggest that delayed or incomplete microenvironmental reprogramming may help explain why most PanIN lesions remain indolent rather than progressing to pancreatic cancer.

24 May 2026

RNA regulator RBM15 linked to immunity, metabolism, and cancer progression

A newly published review article brings attention to the expanding role of RBM15, a critical regulator of RNA m6A methylation, in the development and progression of a wide range of diseases, including cancer, metabolic disorders, and cardiovascular conditions.

24 May 2026

Immunoproteasome plays emerging role in diabetes and metabolic complications

A newly published review article highlights the emerging importance of the immunoproteasome in the development and progression of diabetes and its wide-ranging complications, offering fresh perspectives on future therapeutic strategies.

24 May 2026

RNA regulator YTHDF2 plays key role in controlling inflammation

A new review highlights the emerging importance of YTHDF2, a key regulator of RNA activity, in shaping the body's inflammatory responses and influencing a wide range of diseases.

24 May 2026

Early lung damage patterns uncovered in children with cystic fibrosis

Researchers have mapped how lung damage begins early in life for children with cystic fibrosis, providing new insights that will help reshape future care.

24 May 2026

Scientists visualize a key cell protein regulating inflammatory disease pathways

University of Cincinnati structural biologists are the first in the world to visualize a key cell protein as part of newly published research from the College of Medicine.

22 May 2026

AI-engineered p53 superproteins may reshape future cancer therapies

The Oncodarwinian Hypothesis (OdH) proposes a paradigm shift: cancer is not merely a disease but a potential macro‑immunoadaptive response – a self‑replicating algorithm that can be reprogrammed via AI‑based 3D printed p53 superproteins.

22 May 2026

Pim1 identified as promising therapeutic target for inflammatory arthritis treatment

The research team led by Professor Zhongyu Xie from Sun Yat-sen University revealed a new mechanism by which Pim1 regulated Th17 cell differentiation through mitochondrial metabolism.

22 May 2026

Harvard researchers outline roadmap to solve orphan receptor challenge

A new review highlights how synthetic biology, AI, and spatial omics could transform ligand-receptor discovery from one-by-one searches into network-level mapping.

22 May 2026

Boston Children's scientists create new booster-free mRNA vaccine strategy

In a new study published in Nature Immunology, researchers at Boston Children's Hospital demonstrated that pairing the original COVID-19 mRNA vaccine with an immune system enhancer, known as an adjuvant, extended the duration of the vaccine's protection in mice from a few months up to two years.

22 May 2026

Second-career nursing candidates help solve national staffing shortages

While the usual conversation about our national nursing shortage focuses on how to recruit young people, there is another potential pipeline: people in their 40s and 50s—often pursuing a second career—who are also, in many ways, exactly the nurses that NYU Langone Health needs.

22 May 2026

Optimized extended PCLS culture system extends tissue viability up to two weeks

Precision-cut liver slice (PCLS) technology has long been regarded as a promising ex vivo platform because it preserves the native multicellular architecture of liver tissue.

22 May 2026