Efficacy News and Research

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Engineered CAR-T cells show promise against glioblastoma in preclinical models

With a five-year survival rate of less than 5%, glioblastoma is one of the most aggressive types of brain cancer.

20 Nov 2025

Evaluating the role of stereotactic radiosurgery in craniopharyngioma management

Craniopharyngiomas account for 2–5% of all primary brain tumors and 5–10% of pediatric brain tumors. Despite their benign histology, their location near the hypothalamus, pituitary gland, and optic pathways complicates management.

19 Nov 2025

New NIH grants support research on how brain fluid movement drives glioblastoma spread

Jennifer Munson, a cancer researcher at Virginia Tech's Fralin Biomedical Research Institute at VTC, has been awarded two new National Institutes of Health grants to advance greater understanding and improved treatment of a deadly brain cancer.

19 Nov 2025

Evaluating whether LIT supplementation slows cognitive decline in Alzheimer’s patients

Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by cognitive decline such as memory loss and behavioral disturbances that severely impair quality of life. Despite decades of research, effective disease-modifying therapies remain elusive, underscoring the urgent need for novel neuroprotective strategies.

19 Nov 2025

Herbal garlic mouthwash emerges as a potential alternative to chlorhexidine

Garlic extract demonstrates antimicrobial efficacy comparable to other widely used antiseptics and disinfectants, such as chlorhexidine, according to University of Sharjah medical scientists.

19 Nov 2025

New antibody strategy shows promise for halting cyst growth in polycystic kidney disease

Polycystic kidney disease (PKD) is a debilitating hereditary condition in which fluid-filled sacs form and proliferate in the kidneys. Over time, the painful, growing cysts rob the organs of their function, often leading to dialysis in advanced cases.

18 Nov 2025

Alzheimer’s drugs improve key cognitive skills in children with autism and low IQ

The review synthesizes evidence on whether Alzheimer’s disease medications can improve neurocognitive outcomes in children and adolescents with autism and low IQ. Across 12 studies, preliminary findings show promising gains in language, executive function, learning and memory, and general cognitive ability, particularly in younger children.

18 Nov 2025

Encapsulated hormone therapy strengthens osteoporotic bones while avoiding side effects

Postmenopausal osteoporosis is a condition that weakens bones, making them brittle and prone to fracture.

18 Nov 2025

Advances in diagnosis and management of chronic subdural hematoma

Chronic subdural hematoma (CSDH) is one of the most common neurosurgical conditions, particularly among the elderly, with an annual incidence ranging from 1.7 to 20.6 per 100,000 people.

18 Nov 2025

T cells drive vaccine effectiveness against porcine reproductive and respiratory syndrome virus

A new study shows that the effectiveness of current vaccines against porcine reproductive and respiratory syndrome virus (PRRSV) is due to the response of T cells against the disease, rather than the production of antibodies.

17 Nov 2025

New malaria treatment holds promise against rising drug resistance

The first new malaria treatment in decades holds promise against rising drug resistance after Swiss drugmaker Novartis announced it was as effective at treating the disease as established treatments.

17 Nov 2025

Fondazione Telethon achieves milestone with Waskyra approval for Wiskott-Aldrich Syndrome

Fondazione Telethon announces the positive opinion issued by the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) recommending marketing authorization in the European Union for Waskyra, an ex vivo gene therapy for Wiskott-Aldrich Syndrome (WAS), a rare and life-threatening primary immunodeficiency.

14 Nov 2025

Understanding leptin's dual function in MAFLD pathogenesis

Metabolic dysfunction-associated fatty liver disease (MAFLD) has emerged as a predominant chronic liver condition globally, intricately linked with obesity, type 2 diabetes (T2DM), and metabolic syndrome.

14 Nov 2025

Enhancing the cancer-immunity cycle through innovative vaccines

Therapeutic cancer vaccines have experienced a remarkable resurgence over the past decade, representing a paradigm shift in oncology toward harnessing the immune system's intrinsic ability to combat malignancies.

14 Nov 2025

Transforming colorectal cancer research with patient-derived xenograft models

Patient-derived xenograft (PDX) models are emerging as a transformative tool in colorectal cancer (CRC) research, offering unparalleled insights into tumor biology, drug resistance, and personalized treatment approaches.

14 Nov 2025

Indero announces breakthrough method for early-phase evaluation of topical drugs using quantitative gene expression

Indero is proud to announce the successful completion of an internally funded study that introduces a novel approach to evaluating topical new chemical entities (NCE) in early-phase clinical research.

14 Nov 2025

Off-label GLP-1 use highlights the cultural pressures driving body anxieties

New obesity drugs that were designed to treat diabetes and obesity are increasingly being used off-label by people without these conditions to achieve slimness and social approval rather than health gains. This perspective maps how such pharmacological thinness interacts with stigma, beauty ideals, digital culture, and inequality, and calls for multinational, intersectional research to understand its full impact.

13 Nov 2025

Underweight children face higher risk of stopping ADHD medication early

Children who are underweight are more likely to stop taking their ADHD medication within a year. These are the findings of a study conducted at the University of Gothenburg on methylphenidate, a common pharmacological treatment in ADHD.

13 Nov 2025

Single-cell study reveals how HPV shapes immune landscape in penile cancer

Although penile cancer represents less than 1% of male malignancies, it carries substantial physical and psychological burden, with a five-year survival rate near 50%.

13 Nov 2025

Innovative research reveals FGD3 as a key player in breast cancer cell death

A naturally occurring protein that tends to be expressed at higher levels in breast cancer cells boosts the effectiveness of some anticancer agents, including doxorubicin, one of the most widely used chemotherapies, and a preclinical drug known as ErSO, researchers report.

13 Nov 2025

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Efficacy News and Research

Engineered CAR-T cells show promise against glioblastoma in preclinical models

Evaluating the role of stereotactic radiosurgery in craniopharyngioma management

New NIH grants support research on how brain fluid movement drives glioblastoma spread

Evaluating whether LIT supplementation slows cognitive decline in Alzheimer’s patients

Herbal garlic mouthwash emerges as a potential alternative to chlorhexidine

New antibody strategy shows promise for halting cyst growth in polycystic kidney disease

Alzheimer’s drugs improve key cognitive skills in children with autism and low IQ

Encapsulated hormone therapy strengthens osteoporotic bones while avoiding side effects

Advances in diagnosis and management of chronic subdural hematoma

T cells drive vaccine effectiveness against porcine reproductive and respiratory syndrome virus

New malaria treatment holds promise against rising drug resistance

Fondazione Telethon achieves milestone with Waskyra approval for Wiskott-Aldrich Syndrome

Understanding leptin's dual function in MAFLD pathogenesis

Enhancing the cancer-immunity cycle through innovative vaccines

Transforming colorectal cancer research with patient-derived xenograft models

Indero announces breakthrough method for early-phase evaluation of topical drugs using quantitative gene expression

Off-label GLP-1 use highlights the cultural pressures driving body anxieties

Underweight children face higher risk of stopping ADHD medication early

Single-cell study reveals how HPV shapes immune landscape in penile cancer

Innovative research reveals FGD3 as a key player in breast cancer cell death

Industry Focus eBook - Analytical Chemistry (2nd Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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