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New UAB-developed gene therapy for ALS receives orphan drug designation

The U.S. Food and Drug Administration (FDA) has granted orphan drug designation to a new gene therapy for Amyotrophic Lateral Sclerosis (ALS) developed at the Universitat Autònoma de Barcelona and licensed to the U.S. company Klotho Neurosciences, Inc.

15 Jul 2025

Research explains how low sodium weakens the heart’s electrical signals

New research explains how low levels of the electrolyte sodium in the blood can disrupt the timing of the heartbeat in patients taking widely used rhythm-control medications such as flecainide, which is commonly prescribed for atrial fibrillation and other fast or irregular heart rhythms.

15 Jul 2025

Long sitting hours raise breast cancer odds for inactive obese women

Prolonged daily sitting is linked to a higher prevalence of breast cancer in obese women, but only among those who are physically inactive. Regular physical activity eliminates this association, highlighting the importance of movement for breast cancer prevention in high-risk groups.

15 Jul 2025

Adding nut extract helps keep pork burgers healthier and safer

Researchers found that adding hazelnut skin green extract to pork burgers significantly reduced harmful lipid oxidation during cooking and digestion. This natural by-product may help extend shelf life and offer a clean-label alternative to synthetic preservatives in meat products.

14 Jul 2025

Weight loss drugs can boost testosterone in men with obesity or diabetes

Anti-obesity medications can significantly raise testosterone levels and improve health outcomes for men with obesity or type 2 diabetes, according to a new study being presented Monday at ENDO 2025, the Endocrine Society's annual meeting in San Francisco, Calif.

14 Jul 2025

Vested interests. Influence muscle. At RFK Jr.’s HHS, It’s not pharma. It’s wellness.

On his way to an Ultimate Fighting Championship event, Health and Human Services Secretary Robert F. Kennedy Jr. stopped by the home of podcaster Gary Brecka.

14 Jul 2025

Higher protein intake may help prevent muscle loss in semaglutide users

Women and older adults taking the anti-obesity drug semaglutide may be at higher risk for muscle loss, but higher protein intake may help prevent muscle loss in these patients, according to a small study being presented Saturday at ENDO 2025, the Endocrine Society's annual meeting in San Francisco, Calif.

12 Jul 2025

Combining tirzepatide and hormone therapy boosts weight loss in postmenopausal women

Using tirzepatide and menopause hormone therapy at the same time leads to increased weight loss in postmenopausal women with overweight or obesity compared to use of tirzepatide treatment alone, according to a study being presented Saturday at ENDO 2025, the Endocrine Society's annual meeting in San Francisco, Calif.

12 Jul 2025

Uncovering the hidden architecture of the genome in three dimensions

In biology textbooks and beyond, the human genome and DNA therein typically are taught in only one dimension. While it can be helpful for learners to begin with the linear presentation of how stretches of DNA form genes, this oversimplification undersells the significance of the genome's 3D structure.

12 Jul 2025

Myopenia identified as key contributor to muscle loss in rheumatoid arthritis

Rheumatoid arthritis (RA) is a chronic autoimmune disease that affects individuals across all ages and genders.

11 Jul 2025

Weekly injectable drug offers hope for Parkinson's patients

A new weekly injectable drug could transform the lives of more than eight million people living with Parkinson's disease, potentially replacing the need for multiple daily tablets.

11 Jul 2025

How a simple blood test can forecast future health risks

Plasma proteomics reveals that the biological ages of key organs, especially the brain and immune system, strongly predict the risk of future disease and early death. These organ-specific “clocks” provide a new tool for identifying those at highest risk and personalizing preventive care.

10 Jul 2025

New type of algae offers breakthrough in cell cultivation

The time it takes to grow new skin for burns victims could be improved thanks to a new method of cell cultivation using algae, developed by University of Queensland researchers.

10 Jul 2025

Does pomegranate seed oil really help your heart? New research weighs the evidence

This review explores the potential of punicic acid in pomegranate seed oil as a nutraceutical for cardiovascular health. While preclinical evidence is promising, robust human trials are needed to confirm its benefits.

10 Jul 2025

Lower body temperature found to directly influence glucose metabolism in mice

Some mammals are capable of hibernating during periods of low food availability in an effort to conserve energy and survive.

10 Jul 2025

New molecule linked to muscle loss in people with type 2 diabetes

Researchers at Karolinska Institutet have discovered a previously unknown molecule that may explain why people with type 2 diabetes often suffer from muscle weakness and muscle loss - a condition that has a major impact on quality of life and overall health.

10 Jul 2025

Short-term exercise improves liver health by modulating amino acid metabolism

Metabolic-associated steatohepatitis (MASH) is an advanced and progressive liver disease that potentially causes cirrhosis and hepatocellular carcinoma.

10 Jul 2025

Biological age of the brain emerges as a powerful predictor of longevity

The candles on your birthday cake don't tell the whole story. As anyone who ever attended a high-school reunion can tell you, some people age faster than others.

10 Jul 2025

AI tool outperforms existing methods in diagnosing cardiac amyloidosis

In a new study published in the European Heart Journal, researchers reported the successful development and validation of a medical artificial intelligence (AI) model that screens for cardiac amyloidosis, a progressive and irreversible type of heart disease.

9 Jul 2025

Athletes across sports share core movement efficiencies

New research into the muscles of world-class athletes and performance artists has revealed that a small number of "general motor skills" raise these experts above regional-level and novice competitors, with interesting implications for competitive sport and musculoskeletal health.

9 Jul 2025