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New blood test offers breakthrough in myeloma diagnosis and monitoring

Researchers at Dana-Farber Cancer Institute have developed a blood test that could transform the diagnosis and monitoring of multiple myeloma (MM) and its precursor conditions.

8 Aug 2025

Novel insights from lymphoid structures: Lessons from colorectal cancer research

Discover how lymphoid structures and germinal centers provide powerful prognostic insights into colorectal cancer.

From TissueGnostics 31 Jul 2025

Restricted diet triggers drop in microbial diversity without convergence

According to a recent exploratory study published in eGastroenterology, the answer is more complex than expected. Researchers from KU Leuven and collaborating institutions conducted a tightly controlled dietary intervention, known as the "Oatmeal Study", to examine whether restricting food variety could induce convergence in the gut microbiota across individuals.

22 Jul 2025

Toti-N-Seq breakthrough enables universal and scalable single-cell profiling

The rapid advancement of single-cell and single-nucleus RNA sequencing (sc/snRNA-seq) has opened unprecedented windows into cellular diversity, yet existing methods for multiplexing samples struggle with scalability and accuracy.

22 Jul 2025

DeNovix releases new CellDrop FLxi applications

DeNovix announces the release of three new cell counting applications for the CellDrop FLxi Automated Cell Counter.

From DeNovix Inc. 21 Jul 2025

Shen-Bai-Jie-Du decoction inhibits colorectal tumorigenesis by targeting immunosuppressive dendritic cells

This new article publication from Acta Pharmaceutica Sinica B, discusses how single-cell RNA sequencing reveals that Shen-Bai-Jie-Du decoction retards colorectal tumorigenesis by regulating the TMEM131-TNF signaling pathway-mediated differentiation of immunosuppressive dendritic cells.

12 Jul 2025

Scientists identify key role of T-bet in flu memory B cells

At the surface, the immune response to a flu virus is simple. Some cells recognize the pathogen and send a signal to the immune system, and immune cells produce a potentially lifesaving antibody against the virus. Antigen in, antibody out.

11 Jul 2025

Introducing the iQue® 5 HTS Platform: empowering scientists with unbeatable speed and flexibility for high throughput screening by cytometry

The life science group Sartorius launches the new iQue® 5 High-Throughput Screening (HTS) Cytometer, transforming workflows with next-level flexibility and comprehensive analysis at unbeatable speeds. Building on core iQue® strengths as the market leading solution for HTS applications, the iQue® 5 expands experimental range with up to 27 channels (25 color options) and flexible workflows in 96- and 384-well formats.

From Sartorius 11 Jul 2025

Study provides a molecular snapshot of Tanshi constitution's immunological landscape

The study aims to uncover the immunological basis of Tanshi (phlegm-dampness) constitution—a subhealth type in traditional Chinese medicine (TCM)—using single-cell RNA sequencing (scRNA-seq) of peripheral blood mononuclear cells (PBMCs).

7 Jul 2025

New neurons form in the hippocampus even in late adulthood

A study in the journal Science presents compelling new evidence that neurons in the brain's memory centre, the hippocampus, continue to form well into late adulthood.

4 Jul 2025

Lung cells generated from mouse embryonic fibroblasts in just 7 to 10 days

Researchers in Japan have successfully generated lung cells similar to alveolar epithelial type 2 (AT2) cells from mouse embryonic fibroblasts without using stem cell technology.

3 Jul 2025

Study explores how a familiar spice tackles the toughest cancer cells

Researchers found that clinically achievable doses of curcumin, the active compound in turmeric, target and suppress colorectal cancer stem-like cells, especially in early adenomas. Curcumin shifts these cells toward differentiation, delays tumor growth in mice, and may offer a safe preventive strategy.

27 Jun 2025

Fire smoke exposure found to alter immune system at the cellular level

Exposure to fire smoke-which can be composed of particulate matter, gases, materials from buildings such as perfluoroalkyl and polyfluoroalkyl substances (PFAS), toxic metals, and carcinogenic compounds-may alter the immune system on a cellular level, according to a new study led by researchers at Harvard T.H. Chan School of Public Health.

26 Jun 2025

Inflammatory cells may persist despite biologic therapy in severe asthma

Biological drugs have improved the lives of many people with severe asthma. However, a new study from Karolinska Institutet in Sweden shows that some immune cells with high inflammatory potential are not completely eradicated after treatment.

26 Jun 2025

Study reveals mechanisms behind antibiotic-related immune disruptions in infants

In 2017, scientists at Cincinnati Children's revealed that using antibiotics to protect newborns from dangerous infections often comes with a long-term consequence-a permanently underdeveloped immune system that can make children prone to poor outcomes from future lung infections.

9 Jun 2025

Study aims to demystify the immune toxicity triggered by osimertinib-ICI co-treatment

Non-small cell lung cancer (NSCLC) accounts for the majority of lung cancer cases and remains a leading cause of cancer mortality worldwide.

6 Jun 2025

New electrochemical device advances point-of-care HIV diagnostics

Accurate monitoring of CD4+ T cell counts is vital for evaluating immune health and guiding treatment in people living with Human Immunodeficiency Virus (HIV).

30 May 2025

Researchers report a new avenue for targeted drug delivery

A new avenue for targeted drug delivery has been proposed by researchers from The Grainger College of Engineering at the University of Illinois Urbana-Champaign.

29 May 2025

Fact: You could be inhaling nearly 70,000 plastic particles annually, here's what it means for your health

Airborne microplastics and nanoplastics are increasingly detected in urban environments, with evidence linking inhalation exposure to inflammation, cardiovascular risks, and other health concerns. Researchers highlight urgent needs for improved detection, targeted mitigation strategies, and coordinated global policies to address this emerging threat.

28 May 2025

Discovery unravels two populations of gonadotrophs in the pituitary gland

Researchers at the Francis Crick Institute have shown that gonadotrophs, cells in the pituitary gland with a key role in puberty and reproduction, come from two different populations, with the majority produced after birth rather than in the embryo, as previously thought.

21 May 2025