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Ribonucleic acid (RNA) is a biologically important type of molecule that consists of a long chain of nucleotide units. Each nucleotide consists of a nitrogenous base, a ribose sugar, and a phosphate.

Single-cell transcriptomes of immune cells offer insight into juvenile idiopathic arthritis

Juvenile idiopathic arthritis (JIA), a type of arthritis commonly occurring in children, is a chronic, inflammatory condition that affects the joints, causing pain, swelling, stiffness, and limiting the range of motion.

2 Jul 2025

Targeting RAP proteins for next-generation malaria treatments

A University of California, Riverside-led team has made an advance in the basic understanding of Plasmodium falciparum, the parasite responsible for the deadliest form of human malaria, that could make novel, highly targeted anti-malarial therapies possible.

1 Jul 2025

Scientists trace leprosy’s roots in South America back 4,000 years

Researchers have recovered and sequenced Mycobacterium lepromatosis genomes from 4,000-year-old human remains in Chile, providing the first molecular evidence of ancient leprosy in the Americas. The findings reveal the deep evolutionary roots and complex spread of Hansen’s disease long before European contact.

1 Jul 2025

Researchers uncover how RNA modifications evade immune detection

The innate immune system is the body's first line of defense against pathogens and foreign substances. An essential component of this system are pattern recognition receptors, which recognize non-self RNA - such as that from viruses and bacteria - and trigger an immune response.

1 Jul 2025

Shift Bioscience proposes improved ranking system for virtual cell models to accelerate gene target discovery

Shift Bioscience (Shift), a biotechnology company uncovering the biology of cell rejuvenation to develop new therapies for age driven diseases, today announced the results of a new study detailing an improved approach to ranking virtual cell models for gene discovery.

1 Jul 2025

Rarely studied RNA linked to triple-negative breast cancer

Breast cancer is one of the most common cancers among women in the United States. Thanks to decades of fundamental research, it's also one of the most curable.

1 Jul 2025

Improving RNA drug delivery through intracellular traffic control

A recent study involving researchers from the University of Basel reveals that slowing down the intracellular transport of RNA-based drugs can significantly enhance their effectiveness.

1 Jul 2025

VIRMA protein regulates brain development by controlling ribosome biogenesis

Ribosomes are tiny molecular machines inside all living cells that build proteins, and ribosome biogenesis is the complex, multi-step process by which they are made.

30 Jun 2025

Expanding the genetic code in mammalian cells using pseudouridine modified codons

To overcome the inherent challenge of translation termination interference caused by stop codon reprogramming in mammalian cells, researchers from Peking University led by Chen Peng from College of Chemistry and Molecular Engineering and Yi Chengqi from School of Life Sciences have developed a novel codon expansion strategy that enables precise incorporation of noncanonical amino acids (ncAAs) without perturbing natural genetic codes.

27 Jun 2025

Blood test can reveal early signs of leukemia without bone marrow sampling

What if a blood test could reveal the pace of our aging – and the diseases that may lie ahead? The labs of Profs. Liran Shlush and Amos Tanay at the Weizmann Institute of Science have been conducting in-depth studies into the biology of blood to better understand the aging process and why some people become more susceptible to disease over the years.

27 Jun 2025

New insights into exercise physiology through enduromics and resistomics

Exercise has been recognized as an extremely effective tool to improve human health— it can have a preventative and even therapeutic effect on non-communicable diseases such as diabetes and cardiovascular diseases.

27 Jun 2025

LMU researchers uncover mechanism for metabolism without cell membranes

LMU researchers have demonstrated a possible mechanism for metabolic processes without cell membranes in water-filled pores.

27 Jun 2025

Evolving spectrophotometry for modern biopharma workflows

Explore how spectrophotometry is evolving to deliver speed and accuracy in biopharma workflows.

From Thermo Fisher Scientific – Pharmaceutical and Biopharmaceutical Solutions 27 Jun 2025

Study explores how a familiar spice tackles the toughest cancer cells

Researchers found that clinically achievable doses of curcumin, the active compound in turmeric, target and suppress colorectal cancer stem-like cells, especially in early adenomas. Curcumin shifts these cells toward differentiation, delays tumor growth in mice, and may offer a safe preventive strategy.

27 Jun 2025

New insights into programmed cell death could offer relief for inflammatory bowel disease

New basic science insights into programmed cell death could offer relief for inflammatory bowel disease.

26 Jun 2025

Epigenetic enzyme SETD1B drives aggressive growth in acute myeloid leukemia

Acute myeloid leukemia (AML) is an aggressive cancer affecting the blood and bone marrow that progresses rapidly, making immediate treatment essential.

26 Jun 2025

NANOSPRESSO device brings precision medicine to hospital pharmacies

A new gene therapy delivery device could let hospital pharmacies make personalized nanomedicines to order.

26 Jun 2025

Ribonucleases revealed as key players in Mendelian disorders

A new review brings to light the pivotal role of ribonucleases (RNases) in shaping the molecular foundation of Mendelian disorders.

26 Jun 2025

Parse Biosciences GigaLab to support Mount Sinai researchers in generating one of the largest Alzheimer's and Parkinson's single cell datasets

Parse Biosciences today announced their commitment to support researchers from the Icahn School of Medicine at Mount Sinai in generating one of the largest single cell datasets focused on understanding alternative splicing events in the cells of Alzheimer's and Parkinson's patients.

From Parse Biosciences 26 Jun 2025

Brown University scientists discover protein essential for heart survival

New findings by a team of molecular biologists at Brown University on the critical role of a protein called AIMP3 in heart function could inform new treatments for heart disease.

25 Jun 2025