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Chimeric RNA offers new clues for tailoring prostate cancer therapies

Prostate cancer has distinct genetic properties in different groups of men that can be targeted to improve patient outcomes, UVA Cancer Center researchers have discovered.

24 Apr 2025

Exploring the role of immune checkpoints IDO1 and PDL1 in Cutaneous Leishmaniasis (CL)

Explore how immune checkpoints IDO1 and PDL1 influence the immune response in Cutaneous Leishmaniasis (CL).

From TissueGnostics 24 Apr 2025

NIH study reveals how inflammation affects pain perception

Researchers uncover the cellular and molecular basis for sensing heat and inflammatory pain.

24 Apr 2025

Expansion of mutant blood cells linked to worse cancer outcomes

Researchers from the Francis Crick Institute, UCL, Gustave Roussy and Memorial Sloan Kettering Cancer Center (MSK), have discovered that expansion of mutant blood cells, a phenomenon linked to aging, can be found in cancerous tumors, and this is associated with worse outcomes for patients.

23 Apr 2025

Blocking IL6 pathway may prevent deadly skin ulcers in kidney disease

The global burden of chronic kidney disease (CKD) is rising, with more than 800 million people affected worldwide. Vascular diseases in patients with CKD are unique and grouped as uremic vascular diseases.

23 Apr 2025

iCares bandage offers real time insights into chronic wounds

Caltech professor of medical engineering Wei Gao and his colleagues are envisioning a smart bandage of the future-a "lab on skin" that could not only help patients and caregivers monitor the status of chronic wounds but also deliver treatment and speed up the healing process for those cuts, incisions, scrapes, and burns that are slow to heal on their own.

23 Apr 2025

Scientists unlock secrets of how cells navigate the body

Scientists from St. Jude Children's Research Hospital and the Medical College of Wisconsin have created a data science framework to better understand how cells travel through the body.

23 Apr 2025

San Antonio scientists use machine learning to identify potential treatments for deadly viruses

A team of San Antonio-based biomedical researchers trained a machine learning algorithm to identify more than two dozen viable treatments for diseases caused by zoonotic pathogens that can jump from animal hosts to infect humans.

23 Apr 2025

NIH scientists use AI to sharpen standard eye imaging

Scientists at the National Institutes of Health (NIH) have leveraged artificial intelligence to transform a device designed to see tissues in the back of the eye into one sharp enough to make out individual cells.

23 Apr 2025

UQ plays key role in a national effort to revolutionize prostate cancer treatment

The University of Queensland will play a key role in a national effort to revolutionize treatment for men with prostate cancer.

22 Apr 2025

Disruption of sterol biosynthesis by prescription drugs: A hidden threat to brain development

A powerful editorial published today in Brain Medicine raises alarm about a previously overlooked threat to brain development and public health: the disruption of sterol biosynthesis by common prescription medications.

22 Apr 2025

Research reveals significant increase in ME/CFS cases across England

There are almost two-thirds more people living with ME/CFS in England than previously thought, a study says.

22 Apr 2025

Dr. Jeremie Poschmann's data-driven approach to immunology and translational science

In a wide-ranging Genomic Press Interview, Dr. Jeremie Poschmann of INSERM and Université de Nantes shares the story behind his bold, data-centric approach to immunology and translational science.

22 Apr 2025

Sex differences in substance use patterns among individuals with panic disorder

In a comprehensive Genomic Press peer-reviewed research article, researchers have revealed compelling evidence that biological sex significantly influences substance use patterns among individuals with panic disorder, with implications for both clinical assessment and treatment strategies.

22 Apr 2025

Mitochondrial pyruvate carrier structure solved after fifty years

Fifty years since its discovery, scientists have finally worked out how a molecular machine found in mitochondria, the 'powerhouses' of our cells, allows us to make the fuel we need from sugars, a process vital to all life on Earth.

18 Apr 2025

New tool simplifies genomic research and boosts medical breakthroughs

A University of Virginia School of Medicine scientist and collaborators have developed a much-needed new tool to increase the efficiency of genomic research and accelerate the development of new ways to improve human health.

16 Apr 2025

Humanized liver organoids double survival rate in rodent models

One reason why our livers excel at clearing waste from our blood system is that the organ functions according to three key "zones" that perform specific major tasks.

16 Apr 2025

Breakthrough method creates functional liver organoids

While organoids aim to mimic human organs, the liver's repertoire of complex functions – and thus the energy it needs to operate – have made it challenging for researchers to grow organoids that proliferate and fully function, says Sato. When prioritizing growth and survival in laboratory settings, hepatocytes, the liver's main cells, eventually transformed into cells resembling cholangiocytes, which line the bile duct.

16 Apr 2025

EAT-Lancet planetary diet shows no dementia risk, may protect against Alzheimer’s

In a large Swedish study, researchers found that the environmentally sustainable EAT-Lancet diet does not increase dementia risk and may lower the risk of Alzheimer’s and all-cause dementia, particularly in people without the APOE ε4 gene. The findings support the integration of sustainable diets into dementia prevention strategies.

15 Apr 2025

UVA scientist secures funding to use sound waves for breast cancer therapy

University of Virginia researcher Natasha D. Sheybani, PhD, has received $5.5 million from the federal Department of Defense to support her cutting-edge efforts to use focused sound waves to improve our immune system's ability to battle breast cancer.

15 Apr 2025