Antibody News and Research

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An antibody is a blood protein that is produced in response to and counteracts an antigen. Antibodies are produced in response to disease and help the body fight against the particular disease. In this way, antibodies help the body develop an immunity to disease.

Study uncovers roles of certain brain cells in Alzheimer's plaque formation

A study in Nature Neuroscience found that both neurons and oligodendrocytes contribute to amyloid-β plaque burden in Alzheimer's disease, highlighting new therapeutic targets.

7 Aug 2024

The interplay of liver cancer stem cells and immune cells in tumor microenvironment

The complex dynamics between liver cancer stem cells (CSCs) and immune cells within the tumor microenvironment (TME) are central to the progression of liver cancer. These interactions are critical in creating an immunosuppressive setting that significantly impacts the response to immunotherapy. Liver CSCs, responsible for tumor initiation, metastasis, therapeutic resistance, and recurrence, exhibit heterogeneity and are characterized by various surface markers that contribute to their stemness and metastatic potential.

7 Aug 2024

New target identified for melanoma resistant to current therapies

Some proteins, such as programmed cell death protein 1 (PD1), can stop the immune system from attacking cancer cells and, therefore, support the growth of cancer.

6 Aug 2024

Valproic acid shows promise in reducing COVID-19 severity and hospitalization

Researchers found that valproic acid (VPA), especially when combined with DHA, significantly reduces SARS-CoV-2 infection rates and severity, potentially activating antiviral mechanisms. Epidemiologic data support VPA's role in reducing COVID-19 severity and hospitalization rates.

6 Aug 2024

Mucosal COVID-19 vaccine prevents airborne transmission of SARS-CoV-2

The impact of mucosal versus intramuscular vaccine immunization on airborne infection and transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Syrian hamsters.

5 Aug 2024

FDA accepted PD-L1 inhibitor durvalumab for the treatment of endometrial cancer

On June 14, 2024, the U.S. FDA approved AstraZeneca's Durvalumab (IMFINZI®) for primary advanced or recurrent endometrial cancer with mismatch repair deficiency. Endometrial cancer is the most prevalent gynecologic cancer, with an estimated 66,200 new U.S. cases in 2023.

From Sino Biological Inc. 5 Aug 2024

Study finds fourfold increase in risk of overt hypothyroidism after diagnosis of gestational subclinical hypothyroidism

A new study has shown that subclinical hypothyroidism diagnosed before 21 weeks of pregnancy is associated with more than fourfold higher rates of overt hypothyroidism or thyroid replacement therapy within 5 years of delivery.

2 Aug 2024

Upper airway swabs reveal rich, stable immune memory crucial for respiratory defense

Researchers discovered diverse and stable immune cell populations in the upper respiratory tract, highlighting the critical role of mucosal immunity in COVID-19 and other respiratory diseases.

1 Aug 2024

Highly inflammatory rheumatoid arthritis patients more susceptible to cognitive impairment

Researchers assessed cognitive function among rheumatoid arthritis patients with ongoing inflammatory activity.

1 Aug 2024

Targeting 14 modifiable risk factors from childhood to old age could prevent or delay dementia

Addressing 14 modifiable risk factors, starting in childhood and continuing throughout life, could prevent or delay nearly half of dementia cases, even as people around the world live longer and the number of people with dementia is set to rise dramatically in all countries, according to the third Lancet Commission on dementia prevention, intervention, and care, which is being presented at the Alzheimer's Association International Conference (AAIC 2024).

1 Aug 2024

New treatment option for endometrial cancer shows promise in phase II trial

The latest trial of a new antibody drug that delivers potent chemotherapy directly to cancer cells for patients with advanced or recurrent endometrial cancer moves ahead to be studied further in a phase III trial.

1 Aug 2024

Hamster sera study reveals Omicron subvariants' vast antigenic diversity

Study developed an antigenic map of SARS-CoV-2 variants using hamster sera, revealing substantial antigenic variation among Omicron subvariants and highlighting their distinct immune escape capabilities.

1 Aug 2024

Bird flu cases are going undetected, new study suggests. It’s a problem for all of us.

A new study lends weight to fears that more livestock workers have gotten the bird flu than has been reported.

31 Jul 2024

Neurofilament light chain identified as early marker for Parkinson’s and dementia with Lewy Bodies

Early detection of Alzheimer's disease-related changes in Parkinson's disease and dementia with Lewy bodies could be made possible by monitoring the amyloid-β (Aβ) and phosphorylated tau (p-tau) proteins.

31 Jul 2024

Wildlife species show high SARS-CoV-2 exposure linked to human activity

Researchers found SARS-CoV-2 RNA in six wildlife species and higher seroprevalence in high human activity areas. Seven new human-to-animal transmission events of the Omicron variant were identified.

30 Jul 2024

ACE technology enhances single-cell protein detection with advanced signal amplification

Since the 1950s, researchers have used a famous method invented by Wallace Coulter known as "flow cytometry" to characterize different types of immune cells in research studies and in blood samples from human individuals.

30 Jul 2024

Exploring alemtuzumab in reduced-toxicity conditioning for Asian patients with inborn errors of immunity

Allogeneic hematopoietic cell transplantation (HCT) is a commonly used curative therapy for individuals with inborn errors of immunity (IEI).

28 Jul 2024

COVID pandemic accelerated brain aging, especially in males and deprived groups

The COVID-19 pandemic accelerated brain aging, particularly in males and those from deprived backgrounds, with significant cognitive performance decline in infected individuals. This impact was observed regardless of COVID-19 infection status, highlighting the role of psychosocial stressors.

25 Jul 2024

New review highlights advances in diabetes research and treatment

A new paper surveying advances in diabetes pathogenesis and treatment explores the complex factors contributing to the onset and progression of the disease, suggesting that an understanding of these dynamics is key to developing targeted interventions to reduce the risk of developing diabetes and managing its complications.

25 Jul 2024

Novel antisense therapy targets α-synuclein pathologies in neurodegenerative diseases

TMDU researchers demonstrate proof of concept of antisense nucleic acid therapy to prevent the spread of α-synuclein pathologies in synucleinopathies.

25 Jul 2024

Antibody News and Research

Further Reading

Study uncovers roles of certain brain cells in Alzheimer's plaque formation

The interplay of liver cancer stem cells and immune cells in tumor microenvironment

New target identified for melanoma resistant to current therapies

Valproic acid shows promise in reducing COVID-19 severity and hospitalization

Mucosal COVID-19 vaccine prevents airborne transmission of SARS-CoV-2

FDA accepted PD-L1 inhibitor durvalumab for the treatment of endometrial cancer

Study finds fourfold increase in risk of overt hypothyroidism after diagnosis of gestational subclinical hypothyroidism

Upper airway swabs reveal rich, stable immune memory crucial for respiratory defense

Highly inflammatory rheumatoid arthritis patients more susceptible to cognitive impairment

Targeting 14 modifiable risk factors from childhood to old age could prevent or delay dementia

New treatment option for endometrial cancer shows promise in phase II trial

Hamster sera study reveals Omicron subvariants' vast antigenic diversity

Bird flu cases are going undetected, new study suggests. It’s a problem for all of us.

Neurofilament light chain identified as early marker for Parkinson’s and dementia with Lewy Bodies

Wildlife species show high SARS-CoV-2 exposure linked to human activity

ACE technology enhances single-cell protein detection with advanced signal amplification

Exploring alemtuzumab in reduced-toxicity conditioning for Asian patients with inborn errors of immunity

COVID pandemic accelerated brain aging, especially in males and deprived groups

New review highlights advances in diabetes research and treatment

Novel antisense therapy targets α-synuclein pathologies in neurodegenerative diseases

Using single B cell screening to boost antibody discovery eBook

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