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Ribonucleic acid (RNA) is a biologically important type of molecule that consists of a long chain of nucleotide units. Each nucleotide consists of a nitrogenous base, a ribose sugar, and a phosphate.

Spatial transcriptomics could transform musculoskeletal research

Conventional transcriptomic techniques have revealed much about gene expression at the population and single-cell level—but they overlook one crucial factor: spatial context.

9 Jun 2025

Study reveals 15 hidden genetic risk factors for celiac disease

This comprehensive GWAS reveals 15 new genetic variants linked to celiac disease, offering insights for earlier detection and tailored treatment strategies.

9 Jun 2025

Breakthrough tumor profiling study offers hope for more precise skin cancer care

Every tumor is unique. This makes it difficult to find the most effective therapy for treatment. The Tumor Profiler Center of the University Hospital Zurich, the University of Zurich, ETH Zurich and the University Hospital Basel has now carried out a study in which nine different molecular biological technologies were used to precisely measure the properties of the tumor in four weeks and enable a precise treatment decision.

6 Jun 2025

Scientists unlock potential of cytokine adjuvants in mRNA vaccines

In the quest to design vaccines that better help the body's immune system fight disease, scientists are always looking for more tools for their arsenal.

6 Jun 2025

New technique creates multimeric aptamers for precision virus targeting

We have all heard of antibodies – proteins produced by our bodies to bind to viruses or bacteria, marking them for elimination by the immune system.

6 Jun 2025

Study aims to demystify the immune toxicity triggered by osimertinib-ICI co-treatment

Non-small cell lung cancer (NSCLC) accounts for the majority of lung cancer cases and remains a leading cause of cancer mortality worldwide.

6 Jun 2025

Stanford scientists grow vascularized heart and liver organoids

For over a decade, scientists have been growing organoids - small clusters of cells that mimic a particular organ - to serve as miniature biological models.

6 Jun 2025

Overexpression of two long non-coding RNAs identified in gastric cancer

A new research paper was published in Volume 16 of Genes & Cancer on May 9, 2025, titled "Evaluation of LncRNAs CBR3-AS1 and PCA3 expression in Gastric cancer and their correlation to clinicopathological variables."

6 Jun 2025

Scientists identify genetic clues linking air pollution to neurodegeneration

This review highlights how air pollution and occupational inhalation exposures may contribute to neurodegenerative disorders by triggering epigenetic changes. The authors stress the urgent need for advanced research to identify early biomarkers and guide protective health strategies for high-risk populations.

6 Jun 2025

Maternal exposure to metals rewires infants’ gut and resistance genes

Prenatal exposure to trace elements like selenium, copper, and arsenic can significantly alter the infant gut microbiome, metabolism, and antibiotic resistance gene patterns. These changes appear as early as three months and evolve during the first year of life.

5 Jun 2025

Breakthrough drug delivery system transports genetic therapies directly to the lungs

Scientists have made a key breakthrough for treating respiratory diseases by developing a new drug delivery system that transports genetic therapies directly to the lungs, opening promising possibilities for patients with conditions like lung cancer and cystic fibrosis.

5 Jun 2025

Reverse transcriptase activity found in aging and Alzheimer’s brains

Alzheimer's disease is the most common cause of dementia and affects more than a tenth of Americans aged 65 and older.

5 Jun 2025

Tumor profiling study advances personalized cancer treatment

5 Jun 2025

Understanding how base editing tools work at the molecular level

You may have seen it in the news recently: a baby in Pennsylvania with a rare genetic disorder was healed with a personalized treatment that repaired his specific genetic mutation.

4 Jun 2025

New marker identifies the functional maturity and heterogeneity of stem cell–derived islet organoids

Over 500 million people worldwide suffer from diabetes-a disease that contributes to major complications such as stroke, kidney failure, cancer, and Alzheimer's disease.

4 Jun 2025

UC Irvine researchers uncover altered RNA processing in ALS

UC Irvine researchers conducted a study to better understand the molecular basis of amyotrophic lateral sclerosis (ALS), a neurodegenerative disorder in which patients lose the ability to move, becoming weak and wheelchair bound before dying because they can no longer breathe.

3 Jun 2025

Study: New mRNA vaccine is more scalable and adaptable to continuously evolving viruses

A new type of mRNA vaccine is more scalable and adaptable to continuously evolving viruses such as SARS-CoV-2 and H5N1, according to a study by researchers at University of Pittsburgh School of Public Health and the Pennsylvania State University.

3 Jun 2025

Study uncovers how HSV-1 disables the brain's antiviral defense

Infections caused by herpes simplex virus type 1 (HSV-1) can lead to HSV-1 encephalitis-a rare but deadly condition that inflames the brain.

3 Jun 2025

Molecular stress makes old neurons vulnerable to neurodegenerative diseases

As the global population ages, the risk of developing neurodegenerative diseases such as dementia, Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis (ALS) continues to rise. But the molecular mechanisms behind the deterioration of brain cells have remained elusive.

2 Jun 2025

Gene expression study reveals clues to asbestos-linked mesothelioma

Gene expression leading to alterations in the DNA caused by asbestos exposure may explain the development of Malignant Pleural Mesothelioma (MPM), a rare and aggressive cancer.

31 May 2025