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New algorithms help surgeons make high-stakes transplant decisions in minutes

A new generation of artificial intelligence (AI) tools could help save more patients who need heart transplants by making better use of donor hearts that are currently discarded, according to research presented today by Brian Wayda, MD, at International Society for Heart and Lung Transplantation (ISHLT) 46th Annual Meeting and Scientific Sessions.

22 Apr 2026

Cystic fibrosis therapies significantly reduce the need for pediatric lung transplants

Pediatric lung transplant specialist Christian Benden, MD, described the future for children who need lung transplants: fewer operations overall, but more complex patients and mounting challenges for the teams who care for them. He addressed the 46th Annual Meeting and Scientific Sessions of the International Society for Heart and Lung Transplantation (ISHLT) today in Toronto.

22 Apr 2026

Cleveland Clinic expert proposes global heart allocation to address health inequities

Today at the 46th Annual Meeting and Scientific Sessions of the International Society for Heart and Lung Transplantation (ISHLT), Eileen Hsich, MD, of the Cleveland Clinic, outlined a bold vision for the future of heart transplantation that moves beyond national borders to address global inequities in organ allocation.

22 Apr 2026

Study shows older lung recipients can achieve outcomes comparable to youth

Today at the International Society for Heart and Lung Transplantation (ISHLT) 46th Annual meeting and Scientific Sessions, transplant specialists Brian Keller, MD, PhD, and Thomas Egan, MD debated an ethically fraught question: How old is too old for a lung transplant?

22 Apr 2026

Teen attitudes toward sun protection impact skin cancer prevention behaviors

A new study funded by the National Cancer Institute at the National Institutes of Health finds that how high school students perceive the costs of sun protection and the rewards of tanning play a significant role in whether they practice sun-safe behaviors.

21 Apr 2026

Cognitive decline may signal heart trouble years before a cardiovascular event

In a large ASPREE and ASPREE-XT nested case-control study of older adults without prior cardiovascular disease, people who later experienced a CVD event showed faster cognitive decline beginning roughly 3 to 8 years before the event. Processing speed declined earliest, suggesting that subtle cognitive changes may emerge well before overt cardiovascular disease.

21 Apr 2026

CAR-PRISM trial reports promising results in high-risk smoldering multiple myeloma

Results of the single-center, phase 2 CAR-PRISM (PRecision Intervention Smoldering Myeloma) clinical trial, the first to investigate Chimeric Antigen Receptor (CAR) T-cell therapy in patients with high-risk smoldering multiple myeloma, showed that all 20 patients were negative for minimal residual disease (MRD) within two months of treatment and remained MRD-negative after a median of 15.3 months of follow-up, and none experienced high-grade side effects, according to results presented at the AACR Annual Meeting 2026, held April 17-22, in San Diego, Calif.

21 Apr 2026

NHS grant funds study on the use of weight-loss drugs for treating PCOS

Dr. Shagaf Bakour, a gynecologist and director of medical education at Aston Medical School, has won an NHS research grant to investigate the use of weight-loss drugs in the treatment of polycystic ovary syndrome (PCOS).

21 Apr 2026

Heatwaves above 38 °C significantly spike cardiovascular cases in middle-aged populations

A novel study has revealed a link between extreme weather and the risk of cardiovascular disease among middle-aged and older adults in 157 Chinese cities. Based on a city's climate and location, exposure to extreme heat, cold, and precipitation each increases the risk of heart disease. The findings of the study in the American Journal of Preventive Medicine, published by Elsevier, provide evidence for policymakers across different regions to develop targeted strategies protecting vulnerable populations during extreme climate events.

21 Apr 2026

Trial shows safety of novel KIR-CAR T therapy in solid tumors

An innovative type of CAR T cell therapy, called KIR-CAR, was shown to be safe, with increasing efficacy corresponding to higher doses of the investigational treatment in nine patients with advanced ovarian cancer, mesothelioma or cholangiocarcinoma (bile duct cancer), according to an early report from an ongoing Phase I dose-escalation clinical trial.

20 Apr 2026

WHO-recommended antibiotics ineffective for many neonatal sepsis cases

A major multi-country study has found that WHO-recommended first-line antibiotics for neonatal sepsis are likely to be effective in only one quarter of infections in low- and middle-income countries (LMICs).

20 Apr 2026

Trial shows durable response with preoperative immunotherapy in bowel cancer

Patients with a specific type of bowel cancer who were treated with a short course of immunotherapy before surgery instead of post-op chemotherapy have remained cancer-free after almost three years of follow-up, according to new results from the NEOPRISM-CRC clinical trial led by a team from UCL and UCLH.

20 Apr 2026

Single CAR T infusion shows strong response in smoldering multiple myeloma patients

A single infusion of ciltacabtagene autoleucel (Carvykti) led to a 100% minimal residual disease (MRD)-negativity rate in patients with high-risk smoldering multiple myeloma, according to results from CAR-PRISM, a phase II clinical trial, presented at the American Association for Cancer Research (AACR) Annual Meeting 2026, held April 17-22.

20 Apr 2026

Study links long COVID in kids to worse grades and attention problems

A large NIH-funded RECOVER-Pediatrics study found that children and adolescents meeting the long COVID research threshold were more likely to have caregiver-reported worsening grades, attention difficulties, reduced enjoyment with friends, and greater IEP involvement than peers below the threshold. The findings suggest that pediatric long COVID may affect school and social functioning during key developmental years, although the cross-sectional design does not establish causation.

20 Apr 2026

Simple oral care cuts hospital-acquired pneumonia risk

A landmark trial presented today at ESCMID Global 2026 shows that improving oral hygiene for hospital patients can reduce the risk of non-ventilator-associated hospital-acquired pneumonia (NV-HAP) by 60%.

20 Apr 2026

Study reveals what people ask AI chatbots about health most often

Researchers analyzed more than 500,000 de-identified Microsoft Copilot health conversations from January 2026 and found that health information queries were most common, while nearly one in five conversations involved personal symptoms or condition-related concerns. They also found that personal health queries were more common on mobile and at night, while desktop use was more often tied to research, paperwork, and academic support, highlighting how people use AI differently across contexts.

20 Apr 2026

Certain prenatal medications linked to increased risk of autism

A landmark study led by researchers at the University of Nebraska Medical Center (UNMC) and published in Molecular Psychiatry has identified a significant association between prenatal prescription of commonly utilized medications and the risk of autism spectrum disorder (ASD) in children.

20 Apr 2026

Newborns carry antibiotic resistance genes within first hours of life

Antibiotic resistance genes (ARGs) – segments of DNA that help bacteria survive the effects of antibiotics – can be present in newborns within the first hours of life, according to research presented at ESCMID Global 2026.

20 Apr 2026

Antiretroviral therapy reduces biological aging in people living with HIV

A major study presented today at ESCMID Global 2026 has found that antiretroviral therapy (ART) reduces accelerated biological ageing in people with HIV (PWH) by nearly four years, a finding that could transform how clinicians monitor HIV treatment and long-term health outcomes.

20 Apr 2026