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Scientists uncover new obesity genes that reshape understanding of weight and disease risk

Researchers identified five previously unknown genes linked to obesity by analyzing rare protein-truncating variants across six ancestries. The study reveals how rare and common genetic factors combine to influence BMI and related diseases like diabetes and heart failure.

2 Nov 2025

Lactate and lactylation drive metabolic, epigenetic reprogramming in gynecological cancers

Lactate, once considered a metabolic waste product, is now recognized as a key regulator of cellular homeostasis and disease progression.

31 Oct 2025

Immune cell dysregulation and inflammatory mediators shape epilepsy risk

Emerging evidence implicates immune dysregulation and neuroinflammation in the pathogenesis of epilepsy, yet the causal mechanisms remain unclear.

31 Oct 2025

Study reveals how melanoma evolves to resist immunotherapy

A study led by UCLA Health Jonsson Comprehensive Cancer Center investigators reveals how melanoma, the deadliest form of skin cancer, evolves to resist immunotherapy and identifies a potential strategy to prevent or reverse that resistance.

31 Oct 2025

Studies identify complementary approaches to overcome drug resistance in KRAS G12C–mutant lung cancer

Two companion studies published in Cancer Research from scientists at Moffitt Cancer Center identify distinct but complementary approaches to overcoming drug resistance in KRAS G12C–mutant non-small cell lung cancer.

31 Oct 2025

Novel nanoparticles can deliver an immune-stimulating molecule directly to ovarian tumors

Cancer immunotherapy, which uses drugs that stimulate the body's immune cells to attack tumors, is a promising approach to treating many types of cancer. However, it doesn't work well for some tumors, including ovarian cancer.

31 Oct 2025

Better treatments buoy multiple-myeloma patients, bound by research cuts and racial disparities

For more than a year, Diane Hunter, now 72, had been experiencing vague symptoms — pain in her spine and hips, nausea, exhaustion, thirst, and frequent urination.

31 Oct 2025

Bowhead whale’s secret to long life revealed: precision DNA repair may hold clues for human aging

Researchers discovered that bowhead whales achieve extraordinary longevity and cancer resistance through highly efficient and precise DNA repair mechanisms. A whale-specific protein, CIRBP, enhances genome stability even in human cells, revealing a potential pathway to strengthen DNA repair and slow aging.

30 Oct 2025

Study confirms PSA screening improves survival and safety

After 23 years of follow-up, the European Randomized Study of Screening for Prostate Cancer (ERSPC) confirmed a 13% lower prostate cancer mortality with PSA testing and an improved harm–benefit ratio over time. Risk-based screening could sustain mortality gains while reducing overdiagnosis and unnecessary treatment.

30 Oct 2025

Thiostrepton suppresses rhabdomyosarcoma progression by targeting the PI3K–AKT pathway

Rhabdomyosarcoma (RMS) accounts for up to 10% of childhood cancers and nearly half of pediatric soft tissue sarcomas.

30 Oct 2025

Intraoperative radiation reduces the recurrence rate of pancreatic cancer

Using targeted radiation during surgery - referred to as intraoperative radiation - to eliminate pancreatic cancer cells that have spread to areas around the pancreas, investigators at Johns Hopkins have been able to reduce the recurrence rate around the pancreas to 5%.

30 Oct 2025

TROP2 identified as a promising therapeutic target for renal medullary carcinoma

Researchers at The University of Texas MD Anderson Cancer Center, in collaboration with BostonGene, conducted the largest and most comprehensive molecular analysis of renal medullary carcinoma (RMC), a rare and aggressive form of kidney cancer, leading to the identification of TROP2 as a promising therapeutic target.

30 Oct 2025

New chemotherapeutic agent shows remarkable efficacy against multiple tumor types

A research team led by the Medical University of Vienna, the HUN-REN Research Centre for Natural Sciences and the Eötvös Loránd University in Budapest has developed a groundbreaking new chemotherapeutic agent, LiPyDau, which shows remarkable efficacy against multiple tumor types in preclinical studies.

30 Oct 2025

Therapeutic potential of Scleromitrion diffusum in gastric cancer treatment

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Tumor News and Research

Scientists uncover new obesity genes that reshape understanding of weight and disease risk

Lactate and lactylation drive metabolic, epigenetic reprogramming in gynecological cancers

Immune cell dysregulation and inflammatory mediators shape epilepsy risk

Study reveals how melanoma evolves to resist immunotherapy

Studies identify complementary approaches to overcome drug resistance in KRAS G12C–mutant lung cancer

Novel nanoparticles can deliver an immune-stimulating molecule directly to ovarian tumors

Better treatments buoy multiple-myeloma patients, bound by research cuts and racial disparities

Bowhead whale’s secret to long life revealed: precision DNA repair may hold clues for human aging

Study confirms PSA screening improves survival and safety

Thiostrepton suppresses rhabdomyosarcoma progression by targeting the PI3K–AKT pathway

Intraoperative radiation reduces the recurrence rate of pancreatic cancer

TROP2 identified as a promising therapeutic target for renal medullary carcinoma

New chemotherapeutic agent shows remarkable efficacy against multiple tumor types

Therapeutic potential of Scleromitrion diffusum in gastric cancer treatment

Two microbial metabolites compete to control the cells' protein building machinery

Fundamental challenges and cutting-edge strategies in developing new GBM CAR-T therapies

Research identifies biomarkers in blood to fine-tune breast cancer interventions

Rapamycin shows promise in treating cold tumors with specific gene mutation

Targeting myeloid cells to enhance cancer immunotherapy

Harnessing extracellular vesicles for targeted lung cancer treatment

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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