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Female reproductive hormones may be protective against COVID-19

In an article recently published in Trends in Endocrinology & Metabolism, Graziano Pinna from the University of Illinois in Chicago outlines some of the evidence suggesting that female reproductive hormones may play a role in the sex bias that has been observed in coronavirus disease 2019 (COVID-19).

29 Nov 2020

Could beta-blockers be a potential treatment for COVID-19?

News-Medical spoke to researchers about their latest research into beta-blockers, and how they could potentially be used to treat COVID-19.

27 Nov 2020

BCG vaccination appears to trigger cross-reactive SARS-CoV-2-specific T cell response

Recently, researchers from the Monash University and Monash Medical Centre, Clayton, Victoria, Australia, investigated whether peptide sensitization using BCG can produce cross-reactive T cells specific to SARS-CoV-2. Their study is published on the preprint server, medRxiv.

24 Nov 2020

Favorable clinical outcome for ivermectin in COVID-19 animal model

A team of researchers at the Institut Pasteur in France has found that ivermectin prevented clinical deterioration in infected animals. The drug also reduced the inflammatory cytokines, interleukin-6 and 10 (IL-6 and IL-10) in lung tissue, which leads to more favorable clinical outcomes in treated animals.

23 Nov 2020

Chilblain-like skin lesions reported in adolescents and young adults during the pandemic

A team of investigators in the Department of Dermatology, Hospital Infantil Universitario Niño Jesús, Madrid, Spain and Dermatologia Pediatrica Association, Bari, Italy, say acral ischemic lesions, similar to chilblains, have been reported across the globe throughout the COVID-19 pandemic.

17 Nov 2020

LOX plays a number of key roles in promoting skin and organ fibrosis in scleroderma

A team of researchers at the Medical University of South Carolina (MUSC) has found that the molecule lysyl oxidase (LOX) plays a number of important roles in promoting skin and organ fibrosis in scleroderma, a connective tissue disorder.

17 Nov 2020

Researchers identify anti-inflammatory mechanisms that drive alcohol addiction

Deep within the brain, a small almond-shaped region called the amygdala plays a vital role in how we exhibit emotion, behavior, and motivation.

17 Nov 2020

Study sheds new light on the immune system response to COVID-19

A team of immunology experts from research organizations in Belgium and the UK has come together to apply their pioneering research methods to put individuals' COVID-19 responses under the microscope.

16 Nov 2020

MD Anderson presents positive clinical data from combination cancer therapies at SITC 2020

Promising clinical results with combination treatments for patients with melanoma and lung cancer highlight immunotherapy advances being presented by researchers from The University of Texas MD Anderson Cancer Center at The Society for Immunotherapy of Cancer 35th Anniversary Annual Meeting & Pre-Conference Programs.

11 Nov 2020

Uracil point mutations found in SARS-CoV-2 variants alter innate immune responses

Tohoku University scientists have found that human editing enzymes are likely behind a type of mutation in the COVID-19 virus that stimulates the release of pro-inflammatory molecules called cytokines by immune cells in the body.

11 Nov 2020

Rheumatoid arthritis may increase risk of dying from COVID-19

Researchers in New Zealand and Australia have conducted a study showing that people with rheumatoid arthritis may be at an increased risk of death if they develop coronavirus disease 2019 (COVID-19) after becoming infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

11 Nov 2020

Novel super-activating macrophage receptor could explain hyper-inflammation in severe COVID-19

Immunity is a curious thing. While essential in protecting the body against invading pathogens and foreign antigens, it can also turn against the body and trigger destructive immunological processes. A new study published on the preprint server bioRxiv* in November 2020 reports on the role played by hyperactive macrophages in a range of acute and chronic hyper-inflammatory conditions.

10 Nov 2020

Endothelial cells resistant to SARS-CoV-2 infection

A team of scientists from Imperial College London has conducted a series of in vitro studies to investigate the susceptibility of endothelial cells to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, the causative pathogen of coronavirus disease 2019 (COVID-19).

10 Nov 2020

Daily walnut consumption may reduce the risk of heart disease

Findings from a randomized controlled trial recently published in the Journal of the American College of Cardiology, indicate that people in their 60s and 70s who regularly consume walnuts may have reduced inflammation, a factor associated with a lower risk of heart disease, compared to those who do not eat walnuts.

10 Nov 2020

Exosome-mediated mRNA delivery generates broad immune response to multiple SARS-CoV-2 proteins

Recently, researchers from The Johns Hopkins University School of Medicine, Baltimore, MD, USA, and Capricor Therapeutics, Inc., Beverly Hills, CA, USA, described a new approach to SARS-CoV-2 vaccine development using exosomes to deliver mRNAs that encode the antigens from multiple structural proteins of the virus.

9 Nov 2020

Delirium common after hospital discharge in critically ill COVID-19 patients

Anesthesiologist and other researchers from Michigan Medicine, Ann Arbor, New York Medical College, Valhalla and Center for Consciousness Science, University of Michigan Medical School, Ann Arbor, have reported a case series of critically ill coronavirus disease 2019 (COVID-19) patients who have developed neuropsychological symptoms after having been discharged from the hospital.

8 Nov 2020

HKUST researchers identify new therapeutic targets for Alzheimer's disease

Researchers at the Hong Kong University of Science and Technology have identified new therapeutic targets for Alzheimer's disease (AD) by studying the patients' brain with a newly-developed methodology.

5 Nov 2020

SARS-CoV-2 T-cell immunity is retained for at least six months

Now, a new study published on the preprint server bioRxiv shows that functional SARS-CoV-2-specific T-cell responses are retained for six months following infection. However, the strength of this response depends on the clinical features of the primary infection.

3 Nov 2020

Allergen-depleted, anti-inflammatory fragrance can be used in moisturizers for dry skin sufferers

Researchers have developed a novel allergen-depleted and anti-inflammatory fragrance that can be used in moisturizers for people with extremely dry, xerotic skin. Beiersdorf researchers in Germany report the results of two tests proving the fragrance is anti-inflammatory at today’s 29th EADV Congress, EADV Virtual.

2 Nov 2020

COVID-19 patients at risk of fatal co-infection during ICU stays

Researchers in the UK have conducted a study showing that a high proportion of patients admitted to intensive care units (ICU) with coronavirus disease 2019 (COVID-19) acquire a secondary bacterial co-infection during their hospital stay.

29 Oct 2020

Interleukin 2 News and Research

Female reproductive hormones may be protective against COVID-19

Could beta-blockers be a potential treatment for COVID-19?

BCG vaccination appears to trigger cross-reactive SARS-CoV-2-specific T cell response

Favorable clinical outcome for ivermectin in COVID-19 animal model

Chilblain-like skin lesions reported in adolescents and young adults during the pandemic

LOX plays a number of key roles in promoting skin and organ fibrosis in scleroderma

Researchers identify anti-inflammatory mechanisms that drive alcohol addiction

Study sheds new light on the immune system response to COVID-19

MD Anderson presents positive clinical data from combination cancer therapies at SITC 2020

Uracil point mutations found in SARS-CoV-2 variants alter innate immune responses

Rheumatoid arthritis may increase risk of dying from COVID-19

Novel super-activating macrophage receptor could explain hyper-inflammation in severe COVID-19

Endothelial cells resistant to SARS-CoV-2 infection

Daily walnut consumption may reduce the risk of heart disease

Exosome-mediated mRNA delivery generates broad immune response to multiple SARS-CoV-2 proteins

Delirium common after hospital discharge in critically ill COVID-19 patients

HKUST researchers identify new therapeutic targets for Alzheimer's disease

SARS-CoV-2 T-cell immunity is retained for at least six months

Allergen-depleted, anti-inflammatory fragrance can be used in moisturizers for dry skin sufferers

COVID-19 patients at risk of fatal co-infection during ICU stays

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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