Macrophage News and Research

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A macrophage is a type of white blood cell that surrounds and kills microorganisms, removes dead cells, and stimulates the action of other immune system cells.

Neurons play active role in triggering a defense mechanism that leads to their own damage

Rasmussen's encephalitis is a rare autoimmune disease that primarily affects children and can lead to seizures.

31 Aug 2018

KU Leuven study: Macrophages in the intestine can survive for a long time

Macrophages are specialized immune cells that destroy bacteria and other harmful organisms. KU Leuven scientists, Belgium, have come to the surprising conclusion that some macrophages in the intestines of mice can survive for quite some time.

30 Aug 2018

Use of HIV RNA expression inhibitors restores immune function in HIV patients on cART

Immune activation and inflammation persist in the majority of treated HIV-infected individuals and is associated with excess risk of mortality and morbidity.

28 Aug 2018

Newly discovered target may prevent progression of liver injury to cancer

Problems like obesity and alcoholism appear to chronically trigger in the liver a receptor known to amplify inflammation in response to invaders like bacteria, scientists report.

27 Aug 2018

INRS professors develop innovative strategy to identify leishmanicidal molecules

Leishmania is a microorganism that enters the human body via a sandfly bite. Instead of fleeing the white blood cells deployed by the immune system to destroy it, the parasite allows itself to be swallowed up.

24 Aug 2018

Researchers work to create humanized mouse model to test immunotherapies

If a new anti-cancer drug shows promise in a Petri dish, often the next step is to test the drug's effect in mice. This system tends to work well with drugs that directly target cancer, but breaks down with immunotherapies.

24 Aug 2018

Scientists gain new insight into the immune system and infections

Researchers from Sydney have found that the body contains a special structure that can act as front line soldiers in case of infections. These are the cells that could be the main agents in preserving vaccine-memory, they find.

22 Aug 2018

Researchers engineer peptide nanoparticles to outsmart biological system and target kidney cells

Remember the scene in the movie Mission: Impossible when Tom Cruise has to sneak into the vault? He had to do all sorts of moves to avoid detection. That's what it's like to sneak a targeted drug into a kidney and keep it from getting eliminated from the body.

22 Aug 2018

Researchers reveal insights into how body clock controls inflammatory response

Researchers at RCSI and Trinity College Dublin have revealed insights into how the body clock controls the inflammatory response, which may open up new therapeutic options to treat excess inflammation in conditions such as asthma, arthritis and cardiovascular disease.

21 Aug 2018

Statins may improve conditions of people with rare lung disease

In the first study of its kind, researchers have found that cholesterol-lowering statins may improve the conditions of people with a rare lung disease called autoimmune pulmonary alveolar proteinosis. The research also suggested that two new tests could help diagnose the condition.

17 Aug 2018

E-cigarettes not so safe but still better than cigarettes

According to latest research vaping using e-cigarettes can hasten the death of lung cells by up to fifty times and cause serious lung diseases later in life. This latest study was published in the journal Thorax.

14 Aug 2018

Taking cholesterol-busting pills can effectively treat brutal PAP

Researchers report in Nature Communications they figured out why air sacs in the lungs clog up with a thick substance called surfactant in a brutal disease called Pulmonary Alveolar Proteinosis, and they show taking cholesterol-busting pills called statins can effectively treat the disease.

7 Aug 2018

Researchers identify role of infection-fighting cells in inflamed and damaged tissue

Hookworms infect nearly 430 million people in the world, mostly in countries where sanitation is poor, and people often walk barefoot.

7 Aug 2018

Doxorubicin drug causes heart toxicity by disrupting the immune system

Doxorubicin is a chemotherapy drug widely used in ovarian, bladder, lung, thyroid and stomach cancers, but it carries a harmful side effect. The drug causes a dose-dependent heart toxicity that can lead to congestive heart failure.

7 Aug 2018

Drug that treats diabetes found to exert powerful check on macrophages in controlling inflammation

When tissue is damaged, one of the body's first inflammatory immune-system responders are macrophages, cells which are commonly thought of as "construction workers" that clear away damaged tissue debris and initiate repair.

28 Jul 2018

LYVE-1 protein on macrophages found to be key to artery health

Arteries such as the aorta actively transport oxygenated blood, nutrients and cells throughout the body to keep our tissues functioning normally. Damage to the arteries can result in life-threatening cardiovascular diseases.

27 Jul 2018

Researchers discover new protein that controls level of inflammation-inducing molecule

One of the major therapeutic targets for inflammatory diseases is the inflammation-inducing molecule TNF. However, excess levels of TNF cause side effects and can lead to diseases.

27 Jul 2018

Gene therapy may hold potential to treat people with spinal cord injuries

Delivering a single injection of a scar-busting gene to the spinal cord of rats following injury promotes the survival of nerve cells and improves hind limb function within weeks, according to a study published April 2 in The Journal of Neuroscience.

20 Jul 2018

High-fat diet and systemic inflammation contribute to progression of prostate cancer

Osaka University-led study shows how a high-fat diet and systemic inflammation contribute to prostate cancer progression

18 Jul 2018

Researchers describe key role of enzyme in regulating immune response against Chagas disease parasite

In an article published recently in the journal Nature Communications, researchers affiliated with the University of São Paulo in Brazil describe the central role played by an enzyme called phosphatidylinositol 3-kinase gamma in regulating the immune response against Trypanosoma cruzi, the protozoan parasite that causes Chagas disease.

16 Jul 2018

Macrophage News and Research

Further Reading

Neurons play active role in triggering a defense mechanism that leads to their own damage

KU Leuven study: Macrophages in the intestine can survive for a long time

Use of HIV RNA expression inhibitors restores immune function in HIV patients on cART

Newly discovered target may prevent progression of liver injury to cancer

INRS professors develop innovative strategy to identify leishmanicidal molecules

Researchers work to create humanized mouse model to test immunotherapies

Scientists gain new insight into the immune system and infections

Researchers engineer peptide nanoparticles to outsmart biological system and target kidney cells

Researchers reveal insights into how body clock controls inflammatory response

Statins may improve conditions of people with rare lung disease

E-cigarettes not so safe but still better than cigarettes

Taking cholesterol-busting pills can effectively treat brutal PAP

Researchers identify role of infection-fighting cells in inflamed and damaged tissue

Doxorubicin drug causes heart toxicity by disrupting the immune system

Drug that treats diabetes found to exert powerful check on macrophages in controlling inflammation

LYVE-1 protein on macrophages found to be key to artery health

Researchers discover new protein that controls level of inflammation-inducing molecule

Gene therapy may hold potential to treat people with spinal cord injuries

High-fat diet and systemic inflammation contribute to progression of prostate cancer

Researchers describe key role of enzyme in regulating immune response against Chagas disease parasite

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