Aging News and Research

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Decade-long brain study offers new insights into aging

Researchers from The University of Texas at Dallas' Center for Vital Longevity (CVL) have released the full dataset from a decade-long project designed to track brain and cognitive health as people age and distinguish neurologically healthy paths from those indicating a likelihood of decline.

28 May 2025

Cancer drug combo extends the lifespan of mice by 30%

The combination of two cancer drugs, rapamycin and trametinib, can extend the lifespan of mice by 30%, according to a study led by researchers at UCL and the Max Planck Institute for Biology of Ageing, Germany.

28 May 2025

Study sheds new light on how caffeine can impair sleep and memory recovery

Caffeine is not only found in coffee, but also in tea, chocolate, energy drinks and many soft drinks, making it one of the most widely consumed psychoactive substances in the world.

28 May 2025

Global study shows air pollution could triple heart disease cases by 2045

The study highlights air pollution's role in escalating heart disease, showing increased mortality and disability rates, especially among women and older adults.

28 May 2025

Telehealth in home healthcare faces setbacks amid lack of federal reimbursements

Many home healthcare agencies adopted telehealth services during the COVID-19 pandemic, but the absence of federal reimbursements for these services has led to an increasing number of providers discontinuing these options, a national survey conducted by the University of California, Irvine, and other institutions reveals. Results are published in Health Services Research.

28 May 2025

Intestinal bacteria and their metabolites contribute directly to vascular aging

The aging of the innermost cell layer of blood vessels leads to cardiovascular diseases. Researchers at UZH have now shown for the first time that intestinal bacteria and their metabolites contribute directly to vascular aging.

28 May 2025

Immune microRNAs drive new frontiers in cardiovascular disease research

Cardiovascular diseases (CVDs) continue to dominate global mortality statistics, with immune dysregulation emerging as a central feature in their pathogenesis.

28 May 2025

Combination of trametinib and rapamycin extends lifespan in mice

The researchers were able to show that Trametinib alone extends the lifespan of mice by 5-10%, while Rapamycin alone increases lifespan by 15-20%. Together, the drugs have a combinatorial effect that extends the life of the mice by around 30%.

28 May 2025

Oral 8-aminoguanine protects aging eyes and preserves vision in preclinical study

Oral 8-aminoguanine (8-AG) treatment preserved retinal structure and rod function in aged Fischer 344 rats, significantly reducing oxidative stress and inflammation. These findings highlight the promise of 8-AG as a non-invasive intervention to slow age-related retinal degeneration.

27 May 2025

PAHO highlights surge in yellow fever cases across the Americas in 2025

The Pan American Health Organization (PAHO) has issued a new Rapid Risk Assessment (RRA) on yellow fever in the Americas which shows that the risk to public health remains high due to continued human cases in endemic countries of the Region.

27 May 2025

Rethinking the mitochondrial theory of aging

The human genome is broadly classified into the genome residing in the cell nucleus (nuclear DNA) and the genome residing in the mitochondria (mitochondrial DNA: mtDNA). Mitochondria are cell organelles that produce energy essential for life activities through oxidative phosphorylation (mitochondrial respiration), and mtDNA encodes a set of genes required for mitochondrial respiration.

27 May 2025

Alzheimer’s blood biomarkers predict faster muscle strength loss in older adults

A large Swedish cohort study found that elevated blood biomarkers associated with Alzheimer’s disease—including p-tau217, p-tau181, neurofilament light chain, and GFAP—predict accelerated muscle strength decline over 12 years in dementia-free older adults. These findings suggest that early identification of Alzheimer’s-related biomarkers could help clinicians intervene sooner to prevent sarcopenia and related adverse outcomes in aging populations.

27 May 2025

Affordable HIV drug shows promise in improving vision for diabetic eye disease

An inexpensive, long-approved HIV drug can improve vision in patients with a blinding complication of diabetes more effectively and a much lower cost than many existing treatments, an initial clinical trial suggests.

27 May 2025

Firmicutes bacteria can help maintain bone mass, study suggests

A recent study involving 684 Chinese adults has uncovered a significant connection between gut microbiota, aging, and bone health, particularly in relation to osteoporosis, a condition that weakens bones and increases the risk of fractures.

27 May 2025

Healthcare utilization among the elderly remained stable in Japan despite pandemic challenges

Public healthcare emergencies, such as the COVID-19 pandemic, can drastically disrupt healthcare systems with long-term repercussions.

27 May 2025

New biomarker identified for predicting microvascular health of the kidneys

In a world first, Canadian scientists at the CRCHUM, the hospital research centre affiliated with Université de Montréal, have identified microRNA able to protect small blood vessels and support kidney function after severe injury.

27 May 2025

A ministroke can have major consequences

Kristin Kramer woke up early on a Tuesday morning 10 years ago because one of her dogs needed to go out. Then, a couple of odd things happened.

27 May 2025

MRI scans reveal why young women face higher risk for eating disorders

Advanced high-field MRI reveals distinct microstructural changes in hypothalamic subregions of young women with anorexia nervosa and obesity. These alterations may underlie increased vulnerability to eating disorders and point toward new neurobiological treatment targets.

26 May 2025

Targeting individual frailty traits may prevent falls among the elderly

A new research paper was published in Aging (Aging-US) Volume 17, Issue 4, on April 1, 2025, titled "Examining frailty phenotypes of community-dwelling older adults in Taiwan using the falls risk for older people in the community – Taiwan version (Tw-FROP-Com)."

23 May 2025

Chile joins Alliance for Primary Health Care in the Americas to strengthen primary healthcare

The Ministry of Health of Chile joined the Alliance for Primary Health Care in the Americas, a joint initiative led by the Pan American Health Organization (PAHO), the Inter-American Development Bank (IDB) and the International Bank for Reconstruction and Development (World Bank) through the establishment of the Mesa Consultiva of Primary Health Care in Chile.

23 May 2025