Aging News and Research

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Aging metabolism reduces effectiveness of CAR-T cell therapy

A Ludwig Cancer Research study has discovered that the metabolic decline that accompanies aging impairs the efficacy of CAR-T cell therapy, an immunotherapy in which T cells of the immune system are taken from patients, engineered to target cancer cells and reinfused into the same patients for treatment.

23 May 2025

Detecting balance impairments early could prevent life-threatening falls

As we get older, our bodies stop performing as they once did. We aren't as strong as we once were, we don't see as well as we used to and we start becoming less mobile.

23 May 2025

Global female infertility rates surge, hitting women in their late 30s hardest

Researchers analyzed global data from 1990 to 2021 and found that over 110 million women worldwide were affected by infertility, with a significant rise in age-standardized rates. The study highlights shifting trends, with the greatest burden among women aged 35–39, and projections showing further increases in age-standardized rates by 2050.

22 May 2025

Cutting back on sugary drinks may protect men’s fertility, review finds

Regular consumption of sugar-sweetened beverages is associated with lower sperm count, motility, and increased DNA damage, potentially impairing male reproductive health. This narrative review highlights dose-response effects, mechanisms, and research gaps, calling for further studies on diverse populations.

22 May 2025

Living in disadvantaged neighborhoods linked to earlier menopause

A new study led by the Harvard Pilgrim Health Care Institute highlights the significant impact of living in disadvantaged neighborhoods on the onset of menopause.

22 May 2025

Unlocking the secrets of human longevity and healthy aging

Human healthy aging and longevity are complex phenomena influenced by a dynamic interplay of genetic, epigenetic, metabolic, immune, and environmental factors.

22 May 2025

Catalpol shows neuroprotective effects across multiple neurologic conditions

Announcing a new publication for Acta Materia Medica journal. Neurologic disorders are the leading cause of illness and disability as a result of increased life expectancy and global population aging, highlighting the urgent need and great challenge for discovering neuroprotective agents with better efficacy and minimal side-effects.

22 May 2025

Positive self-perceptions about aging linked to better post-fall physical recovery

There is a strong association between an older person's view of how they are aging and how well they will physically recover after a fall.

22 May 2025

Social engagement linked to longer lifespan in older adults

A study in the Journal of the American Geriatrics Society indicates that social engagement may help older individuals live longer.

22 May 2025

Vitamin D supplements help preserve telomere length in aging adults

Results from the VITAL randomized controlled trial reveal that vitamin D supplementation helps maintain telomeres, protective caps at the ends of chromosomes that shorten during aging and are linked to the development of certain diseases.

21 May 2025

Culturally tailored program helps UK seniors sit less and move more

A UK study found that a 12-week intervention to reduce sedentary behavior was well accepted by ethnically diverse older adults. Participants perceived benefits and suggested culturally tailored, home-based approaches for future health programs.

21 May 2025

New CRISPR technology delivers RNA precisely to repair damaged brain cells

When a neuron in our body gets damaged, segments of RNA produce proteins that can help repair the injury.

21 May 2025

New cases of dementia decline while prevalence continues to increase due to population aging

New cases of dementia in the United States declined from 2015 to 2021, but the number of people living with the condition continued to rise due to population aging, with nearly 2.9 million traditional Medicare beneficiaries (around 12%) living with a dementia diagnosis in 2021, finds a study published by The BMJ today.

21 May 2025

Eating garlic, berries, and tea may support younger, healthier cells

Higher intake of methyl adaptogen foods, such as turmeric, green tea, and berries, was associated with reduced epigenetic age in middle-aged men, according to a secondary analysis of the MDLS trial. These findings support the potential role of specific dietary polyphenols in modulating biological aging, though further research in larger and more diverse populations is needed.

21 May 2025

Herpes virus infection linked to higher Alzheimer’s risk, study shows antiherpetic drugs may help

A large US case-control study found that people diagnosed with herpes simplex virus type 1 (HSV-1) had a higher risk of developing Alzheimer’s disease. Use of antiherpetic medications was associated with a reduced risk of Alzheimer’s in those with HSV-1.

21 May 2025

Exploring the link between microbial balance and aging mechanisms

Aging is a multifaceted process driven by interconnected biological mechanisms, among which genomic instability and telomere attrition stand as primary hallmarks.

20 May 2025

Age-related immune decline reduces CAR-T cell therapy efficacy

As people age, their immune systems become less efficient, posing a challenge for cancer therapies that rely on harnessing immune cells.

20 May 2025

Air pollution fuels artery damage and accelerates heart disease, review finds

Researchers reviewed how air pollution, especially fine particulate matter (PM2.5), drives the development and worsening of atherosclerosis, a leading cause of heart attacks and strokes. Their findings highlight robust links between air pollution exposure, early artery changes, and underlying biological mechanisms fueling cardiovascular risk.

19 May 2025

NELL2 identified as a key regulator of bone formation and fat suppression

A recent study identifies Neural EGFL-like 2 (NELL2), a secreted protein, as a key regulator of bone homeostasis, offering potential therapeutic applications for osteoporosis.

19 May 2025

Lifelong mental health struggles found in young adult cancer survivors

Adolescent and young adult cancer survivors exhibit persistently elevated levels of depression and anxiety throughout their lifespan, but only symptoms of anxiety tend to stabilize in their later years, say University of Michigan researchers.

19 May 2025