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Delayed antiviral treatment still beneficial for immunocompromised COVID-19 patients

Starting antiviral treatment as late as 14 days after infection with SARS-CoV-2 may still be beneficial in hosts with compromised immune systems, who are at greatest risk of developing severe COVID-19, according to researchers in the Center for Translational Antiviral Research at Georgia State University's Institute for Biomedical Sciences.

3 Sep 2024

RNA Therapeutics Core launches at Mass General Brigham to boost circular RNA research

The Mass General Brigham Gene and Cell Therapy Institute (GCTI) today announced it has launched the RNA Therapeutics Core, a first-of-its-kind, state-of-the-art facility and resource to advance the use of RNA technologies within and beyond the Mass General Brigham research ecosystem.

3 Sep 2024

$Finerenone shows promise for heart failure with mildly reduced or preserved ejection fraction$

Finerenone shows promise for heart failure with mildly reduced or preserved ejection fraction

Finerenone reduced the composite of total first and recurrent heart failure (HF) events (hospitalizations for HF or urgent HF visits) and cardiovascular death in patients with HF and mildly reduced or preserved ejection fraction, according to an international clinical trial led by investigators from Brigham and Women's Hospital, a founding member of the Mass General Brigham healthcare system.

2 Sep 2024

NCCS study uses exosomes to overcome resistance to epidermal growth factor receptor inhibitors

In a new study, clinician-scientists and researchers from the National Cancer Centre Singapore (NCCS) have demonstrated the use of exosomes to successfully target squamous cell cancer tumours that are usually resistant to epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs). Their research is the first where exosomes have been applied to target TKI-resistant cancers in Singapore. The findings were published in the journal Developmental Cell last month.

2 Sep 2024

Semaglutide cuts death rates from cardiovascular disease and COVID-19

Patients taking semaglutide injections are less likely to die of any cause, including from cardiovascular disease and infections like COVID-19, an international study led by researchers from Brigham and Women's Hospital, a founding member of the Mass General Brigham healthcare system, finds.

30 Aug 2024

Research highlights media misrepresentation of COVID-19 drug efficacy

A new study from researchers at Wake Forest University School of Medicine is shedding light on how scientific evidence and the uncertainty surrounding three unproven therapeutics were portrayed by the U.S. news media during the early days of the COVID-19 pandemic.

30 Aug 2024

Ishani Malhotra named ‘woman entrepreneur of the year’ by cancer research horizons

Cancer Research Horizons, the innovation arm of Cancer Research UK, announced the winners of its second Innovation & Entrepreneurship Awards at it’s gala dinner on the 20th of March in London.These awards celebrate the UK’s most innovative and enterprising efforts in oncology highlighting those individuals in the industry working hard to translate discoveries into benefits for cancer patients.

From Carcinotech 30 Aug 2024

Carcinotech dominates summer awards season

Over the past six years, Carcinotech has been laser-focused on developing, optimising and commercializing our innovative drug development platform.

From Carcinotech 30 Aug 2024

NIH awards $15.5 million to expand clinical trials inclusion for nursing home residents

A team led by research scientists from the Indiana University School of Medicine and Regenstrief Institute has received funding expected to total $15.5 million from the National Institutes of Health's National Institute on Aging to establish a national network structure to include more nursing home residents in clinical trials.

29 Aug 2024

Mapping DNA’s hidden knot-like structures may revolutionize disease treatment

Innovative study of DNA's hidden structures may open up new approaches for treatment and diagnosis of diseases, including cancer.

29 Aug 2024

Nanodrug targeting miR-10b shows promise in treating metastatic breast cancer

A new research paper was published in Oncotarget's Volume 15 on August 26, 2024, entitled, "Inhibition of miR-10b treats metastatic breast cancer by targeting stem cell-like properties."

29 Aug 2024

Kidney donors' mortality risk drops significantly over the past decade

The risk of death for people who donate a kidney for transplantation - already small a decade ago - has dropped by more than half since then, a new study shows.

28 Aug 2024

TCT 2024 to feature latest advances in interventional cardiovascular medicine

The Cardiovascular Research Foundation is pleased to announce the late-breaking clinical trials and science to be featured at TCT 2024.

28 Aug 2024

Self-assembling heart stimulator can correct heart arrhythmia in emergency situations

By injecting a solution of nanoparticles around the heart, a temporary heart stimulator self-assembles, which can correct heart arrhythmia in emergency situations with the help of an external power source.

27 Aug 2024

New techniques in RNA engineering promise longer-lasting therapies

New methods to shape RNA molecules into circles could lead to more effective and long-lasting therapies, shows a study by researchers at the University of California San Diego.

27 Aug 2024

Common chemotherapy supplement weakens the pancreatic cancer's defenses in mice

The fight against cancer is an arms race, and one of the most effective weapons in clinicians' arsenals is immunotherapy. Immune checkpoint therapy has become the standard for treating several types of cancer.

27 Aug 2024

New method uncovers hidden cancer targets

Fighting cancer effectively often involves stopping cancer cells from multiplying, which requires understanding the proteins that the cells rely on to survive.

27 Aug 2024

Stem cell study identifies unique glial contributions to multiple sclerosis

A team of scientists from The New York Stem Cell Foundation (NYSCF) Research Institute and Case Western Reserve University has created the largest reported collection of stem cell models from multiple sclerosis (MS) patients and used them to identify unique ways in which glia – integral support cells in the brain – contribute to the disease.

26 Aug 2024

How diet shapes gut microbiota and affects brain function

Researchers discuss the diet-microbiota-gut-brain axis, which describes the role of both diet and gut microbiota composition on cognitive and emotional health.

26 Aug 2024

Gut microbe metabolite found to modulate heart disease risk through β2-adrenergic receptors

Study identifies phenylacetylglutamine (PAGln), a gut microbiome metabolite, as a novel allosteric modulator of β2-adrenergic receptors, offering insights into its role in cardiovascular disease (CVD) risk.

26 Aug 2024

Therapeutics News and Research

Delayed antiviral treatment still beneficial for immunocompromised COVID-19 patients

RNA Therapeutics Core launches at Mass General Brigham to boost circular RNA research

Finerenone shows promise for heart failure with mildly reduced or preserved ejection fraction

NCCS study uses exosomes to overcome resistance to epidermal growth factor receptor inhibitors

Semaglutide cuts death rates from cardiovascular disease and COVID-19

Research highlights media misrepresentation of COVID-19 drug efficacy

Ishani Malhotra named ‘woman entrepreneur of the year’ by cancer research horizons

Carcinotech dominates summer awards season

NIH awards $15.5 million to expand clinical trials inclusion for nursing home residents

Mapping DNA’s hidden knot-like structures may revolutionize disease treatment

Nanodrug targeting miR-10b shows promise in treating metastatic breast cancer

Kidney donors' mortality risk drops significantly over the past decade

TCT 2024 to feature latest advances in interventional cardiovascular medicine

Self-assembling heart stimulator can correct heart arrhythmia in emergency situations

New techniques in RNA engineering promise longer-lasting therapies

Common chemotherapy supplement weakens the pancreatic cancer's defenses in mice

New method uncovers hidden cancer targets

Stem cell study identifies unique glial contributions to multiple sclerosis

How diet shapes gut microbiota and affects brain function

Gut microbe metabolite found to modulate heart disease risk through β2-adrenergic receptors

Industry Focus eBook - Microbiome (1st edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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